⚠ Provisional — human review required. Tiers are computationally assigned. Per OSMF Grading Methodology §5, every Tier 1/2 entry must be verified against the source paper before publication.
🦠 Long COVID / PASC

Therapeutic Agents
Long COVID / PASC

Evidence-graded candidate agents from the OSMF discovery pipeline. Click any source count to see linked trial and paper references.

205Agents
201Tier 1 (LC RCT)
2Tier 2 (Related RCT)
2815Source entries
Evidence tiers: T1 — RCT in LC/PASC/PACVS T2 — RCT in related condition T3 — Observational in LC T4 — Case series T5 — Case report T6 — Mechanistic / preclinical
205 agents
11C-PS13
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06920628 ↗PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Seque
ACT-based group therapy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06897553 ↗ACT for Mental Health in Neurological Disorders
AER002
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
7 sources
  • T1REGISTERED-ONLY NCT05877508 ↗Anti-SARS-CoV-2 Monoclonal Antibodies for Long COVID (COVID-19)
  • T6 39947217 ↗Targeting the SARS-CoV-2 reservoir in long COVID
  • T6 38432691 ↗Emerging anti-spike monoclonal antibodies against SARS-CoV-2
  • T6 42325367 ↗Long COVID: current research and future directions
  • T6 PMC12982061 ↗Candidate treatments for long COVID: a narrative review of expert and patient-driven priorities
  • T6HARM 38221576 ↗A First-in-Human Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Neutrali
  • T6INDIRECT 41357034 ↗Exploring the Effects of Pemivibart Monoclonal Antibody Infusion in Long COVID: A Case Series Offeri
ATCell
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT05669261 ↗Treatment of Long COVID Symptoms Utilizing Autologous Stem Cells Following COVID-19 Infection
  • T6 41235241 ↗Therapeutic challenges in central nervous system viral infections: advancing mesenchymal stem cell-b
AXA1125
T1
T1 — RCT in LC/PASC/PACVS
Harm signalLong COVID
17 sources
  • T1HARM NCT05152849 ↗Efficacy, Safety, Tolerability of AXA1125 in Fatigue After COVID-19 Infection
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 36642173 ↗A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19
  • T6INDIRECT 39356507 ↗Lithium Aspartate for Long COVID Fatigue and Cognitive Dysfunction: A Randomized Clinical Trial
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6 37445634 ↗Laboratory Findings and Biomarkers in Long COVID: What Do We Know So Far? Insights into Epidemiology
  • T6 37316880 ↗Long COVID: Costs for the German economy and health care and pension system
  • T6INDIRECT 38322108 ↗Autoimmunity and long COVID in children
  • T6INDIRECT 39536116 ↗Translating insights into therapies for Long Covid
  • T6INDIRECT 41928318 ↗Living evidence syntheses for long COVID therapeutics: combining rigorous protocols to build efficie
  • T4 PPR664005 ↗Laboratory Findings and Biomarkers in Long COVID: What Do We Know So Far? Insights Into Epidemiology
  • T6 39718498 ↗<sup>1</sup>H and <sup>31</sup>P MR Spectroscopy to Assess Muscle Mitochondr
  • T6 40792393 ↗Mitochondrial function is impaired in long COVID patients
  • T6 40384184 ↗Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management
  • T6 39382470 ↗Long COVID syndrome: An unfolding enigma
  • T6 36369208 ↗Long COVID and rheumatology: Clinical, diagnostic, and therapeutic implications
Auricular transcutaneous vagus nerve stimulation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
3 sources
  • T1 NCT05679505 ↗Vagus Nerve Stimulation for Post-COVID Syndrome
  • T1 41927730 ↗Post-exercise auricular vagus nerve stimulation modulates autonomic and recovery responses in physic
  • T6 36769845 ↗A Prospect to Ameliorate Affective Symptoms and to Enhance Cognition in Long COVID Using Auricular T
Beclomethasone
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
18 sources
  • T1 NCT05970731 ↗Directed Topical Drug Delivery for Treatment for PASC Hyposmia
  • T6INDIRECT 40396505 ↗Vaccines for preventing infections in adults with haematological malignancies
  • T6INDIRECT 34456675 ↗Steroids and Olfactory Training for Postviral Olfactory Dysfunction: A Systematic Review
  • T6INDIRECT 40455452 ↗Acceptance and Commitment Therapy-Based Parenting Program in Children With Co-Occurring Asthma and A
  • T6 35096502 ↗A Comprehensive Review on Novel Liposomal Methodologies, Commercial Formulations, Clinical Trials an
  • T6 35887512 ↗<i>Trichophyton indotineae</i>-An Emerging Pathogen Causing Recalcitrant Dermatophytoses in India an
  • T6 35373533 ↗International consensus statement on allergy and rhinology: Olfaction
  • T6INDIRECT 33875508 ↗'Long COVID' syndrome
  • T6HARM 34147798 ↗Occurrence and risk assessment of pharmaceuticals and personal care products (PPCPs) against COVID-1
  • T6HARM 38664701 ↗The effectiveness of pharmacist-led educational model in adult patients with allergic rhinitis: a si
  • T6INDIRECT 34379888 ↗Pediatric P-ANCA vasculitis following COVID-19
  • T6INDIRECT 34810106 ↗Post-COVID-19 interstitial lung disease presenting with profound hypoxemia: Report of three cases de
  • T6INDIRECT 37100206 ↗Aerosol pulmonary immune engineering
  • T6INDIRECT 36450371 ↗Inhaled corticosteroids for the treatment of COVID-19
  • T6 35300976 ↗Sex and Gender in Lung Disease and Sleep Disorders: A State-of-the-Art Review
  • T6 39861782 ↗Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques
  • T6 36243331 ↗Glucocorticoids and COVID-19
  • T6 39457048 ↗Immunity and Coagulation in COVID-19
CBDRA60 supplement
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT04777981 ↗(CBDRA60) to Prevent or Reduce Symptoms of COVID-19 and Prevention of Post-Acute Sequelae of SARS-Co
CCT Long COVID
T1
T1 — RCT in LC/PASC/PACVS
Harm signalLong COVID
1 source
  • T1HARM NCT05582603 ↗Safety and Dosage of a Computerized Cognitive Training Program for Cognitive Dysfunction After COVID
CI-581a
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT05690503 ↗Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Seque
  • T6 38711990 ↗Management of cognitive impairment associated with post-COVID-19 syndrome: recommendations for prima
  • T6 37680987 ↗The current landscape of long COVID clinical trials: NIH's RECOVER to Stanford Medicine's STOP-PASC
CI-581b
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
4 sources
  • T1REGISTERED-ONLY NCT05690503 ↗Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Seque
  • T6 39828632 ↗Loneliness-associated factors among older adults: Focus on friendship type and number of friends
  • T6 32973385 ↗Taxonomic revision of the Andean genus <i>Xenophyllum</i> (Compositae, Senecioneae)
  • T6 37680987 ↗The current landscape of long COVID clinical trials: NIH's RECOVER to Stanford Medicine's STOP-PASC
CO-OP Procedures
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
COVIDEx
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
11 sources
  • T1REGISTERED-ONLY NCT06156176 ↗Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomize
  • T6 35165665 ↗The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury
  • T6 36671402 ↗Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agent
  • T6 35988361 ↗Audiological profile of adult Long COVID patients
  • T6 37249533 ↗Comparison of High-Intensity Interval Training to Moderate-Intensity Continuous Training for Functio
  • T6 37520616 ↗A COVID-19 Search Engine (CO-SE) with Transformer-based architecture
  • T6 41213692 ↗Pursuing Reduction in Fatigue After COVID-19 via Exercise and Rehabilitation (PREFACER): a protocol
  • T6INDIRECT 37360228 ↗COVID-19 knowledge deconstruction and retrieval: an intelligent bibliometric solution
  • T6 37559650 ↗COVID-19 progression in hospitalized patients using follow-up <i>in vivo</i> CT and <i>ex vivo</i> m
  • T6 40063348 ↗VITALdb: to select the best viroinformatics tools for a desired virus or application
  • T6 37630599 ↗COVID Variants, Villain and Victory: A Bioinformatics Perspective
Cardiac Rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
22 sources
  • T1REGISTERED-ONLY NCT05530317 ↗CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVI
  • T6INDIRECT 36223120 ↗Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic R
  • T6INDIRECT 36382632 ↗Clinical assessment of endothelial function in convalescent COVID-19 patients: a meta-analysis with
  • T6INDIRECT 33284353 ↗Rehabilitation setting during and after Covid-19: An overview on recommendations
  • T6INDIRECT 36111511 ↗Heart failure during the COVID-19 pandemic: clinical, diagnostic, management, and organizational dil
  • T6INDIRECT 35868671 ↗Long COVID-19: The Need for an Interdisciplinary Approach
  • T6INDIRECT 38551518 ↗Barriers and facilitators for increased accessibility to quality rehabilitation services in low- and
  • T6INDIRECT 36554860 ↗Effectiveness of an Inpatient Virtual Reality-Based Pulmonary Rehabilitation Program among COVID-19
  • T6INDIRECT 38917451 ↗Effects of Cardiopulmonary Rehabilitation on Cardiorespiratory Fitness and Clinical Symptom Burden i
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6INDIRECT 35360229 ↗A Useful Blood Flow Restriction Training Risk Stratification for Exercise and Rehabilitation
  • T6INDIRECT 32475821 ↗The Stanford Hall consensus statement for post-COVID-19 rehabilitation
  • T6INDIRECT 36202135 ↗Clinical guidelines for the use of lifestyle-based mental health care in major depressive disorder:
  • T6INDIRECT 32635468 ↗Frailty and COVID-19: A Systematic Scoping Review
  • T6 34200325 ↗Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors
  • T6 34368201 ↗Serum Metabolic Profile in Patients With Long-Covid (PASC) Syndrome: Clinical Implications
  • T6 37827576 ↗Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort
  • T6 33957805 ↗Early experiences of rehabilitation for individuals post-COVID to improve fatigue, breathlessness ex
  • T6 35176758 ↗Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
Cardiopulmonary exercise training
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
7 sources
  • T1 NCT05035628 ↗Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
  • T6INDIRECT 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T1 35409815 ↗Cardiopulmonary Rehabilitation in Long-COVID-19 Patients with Persistent Breathlessness and Fatigue:
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6INDIRECT 34435313 ↗A spark of hope: histopathological and functional recovery after critical COVID-19
  • T6 41586300 ↗Knowledge Gaps and Controversies on Cardiopulmonary Exercise Testing in the Assessment of Pulmonary
  • T6 40943482 ↗Precision Medicine Study of Post-Exertional Malaise Epigenetic Changes in Myalgic Encephalomyelitis/
Celecoxib
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDPOTS
44 sources
  • T1REGISTERED-ONLY NCT07597902 ↗SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction
  • T6INDIRECT 36219278 ↗Circulating Tumor DNA, Imaging, and Carcinoembryonic Antigen: Comparison of Surveillance Strategies
  • T6INDIRECT 34659109 ↗COVID-19-Associated Subacute Thyroiditis: Evidence-Based Data From a Systematic Review
  • T6INDIRECT 35893864 ↗The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musc
  • T6INDIRECT 37091856 ↗Subacute thyroiditis following COVID-19: A systematic review
  • T6INDIRECT 35395090 ↗The development of inflammatory arthritis following SARS-CoV-2 infection: a systematic review of the
  • T6INDIRECT 40597703 ↗Subacute thyroiditis as a post-COVID-19 complication: a systematic review
  • T1 37660680 ↗Efficacy and safety of celecoxib monotherapy for treatment of moderate depressive symptoms following
  • T6INDIRECT 41562079 ↗Patient-reported improvements from use of IMC-2 alone and IMC-2 and Paxlovid&lt;sup&gt;®&lt;/sup&gt;
  • T6 35039676 ↗Immune targets for therapeutic development in depression: towards precision medicine
  • T6 23988267 ↗Molecular mechanisms underlying chronic inflammation-associated cancers
  • T6 33733315 ↗COVID-19 and the clinical course of rheumatic manifestations
  • T6 32840756 ↗Pain Management During the COVID-19 Pandemic
  • T6INDIRECT 29926477 ↗Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent
  • T6INDIRECT 29694674 ↗Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent
  • T6INDIRECT 24683057 ↗Pharmacological interventions for prevention or treatment of postoperative pain in people undergoing
  • T6INDIRECT 33179245 ↗Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults
  • T6INDIRECT 36269595 ↗Antidepressants for hip and knee osteoarthritis
  • T6INDIRECT 31207169 ↗The Efficacy, Tolerability, and Joint Safety of Fasinumab in Osteoarthritis Pain: A Phase IIb/III Do
  • T6INDIRECT 31680610 ↗Outpatient total hip or knee arthroplasty in ambulatory surgery center versus arthroplasty ward: a r
  • T6INDIRECT 24954491 ↗Role of preoperative pain, muscle function, and activity level in discharge readiness after fast-tra
  • T6 25081580 ↗Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsess
  • T6INDIRECT 33409010 ↗Reactive Arthritis After COVID-19 Infection
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 33421734 ↗The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacol
  • T6INDIRECT 34015983 ↗SARS-COV-2-related immune-inflammatory thyroid disorders: facts and perspectives
  • T6INDIRECT 36736220 ↗Lung fibrosis: Post-COVID-19 complications and evidences
  • T6 38868666 ↗Alzheimer's disease and its treatment-yesterday, today, and tomorrow
  • T6 39861782 ↗Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques
  • T6 37759498 ↗A Molecular Troika of Angiogenesis, Coagulopathy and Endothelial Dysfunction in the Pathology of Ava
  • T6 37251376 ↗The chemokine landscape: one system multiple shades
  • T6INDIRECT 26084539 ↗International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors
  • T6INDIRECT 20357277 ↗Pain management in the cirrhotic patient: the clinical challenge
  • T6INDIRECT 27973405 ↗Chronic Pain in Children and Adolescents: Diagnosis and Treatment of Primary Pain Disorders in Head,
  • T6INDIRECT 37139824 ↗American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medicatio
  • T6INDIRECT 21445724 ↗European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological
  • T6INDIRECT 23227356 ↗Ehlers-danlos syndrome, hypermobility type: an underdiagnosed hereditary connective tissue disorder
  • T6 20696139 ↗Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic dise
  • T6 23588782 ↗Applications of CYP450 testing in the clinical setting
  • T6 29315692 ↗Comprehensive review of cardiovascular toxicity of drugs and related agents
  • T6 30712918 ↗Type 2 diabetes mellitus and osteoarthritis
  • T6 30578418 ↗Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
  • T6 30354828 ↗Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the Ameri
  • T6 22066560 ↗Why still in hospital after fast-track hip and knee arthroplasty?
CogniFit's CCT Post COVID-19
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05571852 ↗Personalized Computerized Training Program for Cognitive Dysfunction After COVID-19
Cold Atmospheric Plasma
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
12 sources
  • T1 NCT07279272 ↗The Effect of the Human Regenerator Jet Device on the Quality of Life of Adult Individuals [HR-QoL]
  • T6 40124344 ↗Treatment of lung diseases &lt;i&gt;via&lt;/i&gt; nanoparticles and nanorobots: Are these viable alt
  • T6 36421668 ↗Review of Developments in Combating COVID-19 by Vaccines, Inhibitors, Radiations, and Nonthermal Pla
  • T6 40843597 ↗European S2k Guideline on Chronic Pruritus
  • T6 38257957 ↗Cold Atmospheric Helium Plasma in the Post-COVID-19 Era: A Promising Tool for the Disinfection of Si
  • T6 37290960 ↗EACR 2023: Innovative Cancer Science, 12-15 June 2023, Torino, Italy
  • T6INDIRECT 41930351 ↗Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
  • T6INDIRECT 40917828 ↗Medical gases in respiratory diseases: ozone, argon, and nitric oxide as game-changers in therapeuti
  • T4 PMC10206698 ↗E-Poster abstracts
  • T4 PMC9931687 ↗Abstracts
  • T4 PMC7650373 ↗Full SNO 2020 Abstracts PDF
  • T6 36451994 ↗Coronavirus outbreaks and infection prevention in dentistry: a narrative review
Compass 31
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
25 sources
  • T1REGISTERED-ONLY NCT06027255 ↗Long COVID Immune Profiling
  • T6INDIRECT 34509649 ↗Post-COVID syndrome. A case series and comprehensive review
  • T6INDIRECT 41973314 ↗Stellate Ganglion Block in the Treatment of Long COVID: A Systematic Review
  • T6INDIRECT 39987007 ↗Exercise rehabilitation for people with postural tachycardia syndrome at two secondary care centres
  • T6INDIRECT 39374820 ↗Inspiratory muscle training improves autonomic function in myalgic encephalomyelitis/chronic fatigue
  • T6INDIRECT 36042189 ↗A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pand
  • T6INDIRECT 34386903 ↗Autonomic dysfunction in post-COVID patients with and witfhout neurological symptoms: a prospective
  • T6 36326545 ↗Psychiatric and neurological complications of long COVID
  • T6 34069603 ↗European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE): Expert Consensus
  • T6 36410797 ↗HEART rate variability biofeedback for long COVID symptoms (HEARTLOC): protocol for a feasibility st
  • T6 38454468 ↗IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in
  • T6INDIRECT 34821709 ↗Post-Acute Sequelae of COVID-19 and Cardiovascular Autonomic Dysfunction: What Do We Know?
  • T6INDIRECT 34265539 ↗Preparing for the long-haul: Autonomic complications of COVID-19
  • T6INDIRECT 36580747 ↗Investigating the possible mechanisms of autonomic dysfunction post-COVID-19
  • T6INDIRECT 38390594 ↗Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome?
  • T6INDIRECT 33927679 ↗COVID-19 Dysautonomia
  • T6 37390745 ↗Molecular mimicry and autoimmunity in the time of COVID-19
  • T6 38396973 ↗Autoimmune Autonomic Neuropathy: From Pathogenesis to Diagnosis
  • T6 40002491 ↗Small-Fiber Neuropathy: An Etiology-Oriented Review
  • T6 38362266 ↗Meaningful digital biomarkers derived from wearable sensors to predict daily fatigue in multiple scl
  • T6 38873615 ↗Antibody-mediated autoimmunity in symptom-based disorders: position statement and proceedings from a
  • T6 39888240 ↗Small fiber neuropathy in the post-COVID condition and Myalgic Encephalomyelitis/Chronic Fatigue Syn
  • T6 39526678 ↗Small fiber neuropathy associated with COVID-19 infection and vaccination: A prospective case-contro
  • T6 36283919 ↗Long COVID: An inevitable sequela of SARS-CoV-2 infection
  • T6 36353127 ↗Characterization of autonomic symptom burden in long COVID: A global survey of 2,314 adults
Complementary and Integrative Medicine online intervention, routine care and book
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06004362 ↗Complementary and Integrative Medicine as an Online Intervention in Patients With Post-covid Syndrom
Complementary self-help strategies in addition to treatment as usual
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05798221 ↗Complementary Self-help Strategies for Patients With Post-COVID-19 Syndrome
Comprehensive Rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
30 sources
  • T1 NCT06156202 ↗Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve
  • T6INDIRECT 41057923 ↗Health-related quality of life in COVID-19 patients: a systematic review and meta-analysis of EQ-5D
  • T6INDIRECT 40083165 ↗Effect of pulmonary rehabilitation for patients with long COVID-19: a systematic review and meta-ana
  • T6INDIRECT 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T6INDIRECT 34540862 ↗Follow-Ups on Persistent Symptoms and Pulmonary Function Among Post-Acute COVID-19 Patients: A Syste
  • T6INDIRECT 38551518 ↗Barriers and facilitators for increased accessibility to quality rehabilitation services in low- and
  • T6INDIRECT 38214046 ↗Evidence-based position paper on physical and rehabilitation medicine professional practice for pers
  • T6INDIRECT 39978856 ↗Post-Hospitalisation COVID-19 Rehabilitation (PHOSP-R): a randomised controlled trial of exercise-ba
  • T6INDIRECT 36554860 ↗Effectiveness of an Inpatient Virtual Reality-Based Pulmonary Rehabilitation Program among COVID-19
  • T6INDIRECT 33831043 ↗Post-COVID-19 syndrome among symptomatic COVID-19 patients: A prospective cohort study in a tertiary
  • T6 32817258 ↗COVID-19: interim guidance on rehabilitation in the hospital and post-hospital phase from a European
  • T6 34051516 ↗Physical and mental health complications post-COVID-19: Scoping review
  • T6 32669623 ↗Survivorship after COVID-19 ICU stay
  • T6INDIRECT 36159093 ↗Rehabilitation in long COVID-19: A mini-review
  • T6INDIRECT 35968401 ↗Post-COVID lung disease(s)
  • T6INDIRECT 34240576 ↗Providing rehabilitation to patients recovering from COVID-19: A scoping review
  • T6INDIRECT 34133481 ↗Rehabilitation of patients after COVID-19 recovery: An experience at the Physical and Rehabilitation
  • T6INDIRECT 38081885 ↗Clinical characteristics of Long COVID patients presenting to a dedicated academic post-COVID-19 cli
  • T6INDIRECT 34160029 ↗Apparent Discordance Between the Epidemiology of COVID-19 and Recommended Outcomes and Treatments: A
  • T6 39267913 ↗Evaluation of fibroblast activation protein-specific PET/CT in a patient with post-COVID pneumonitis
  • T6 37077114 ↗Clinical effectiveness of medical ozone therapy in COVID-19: the evidence and gaps map
  • T6 38579075 ↗Advances in the application of traditional Chinese medicine during the COVID-19 recovery period: A r
  • T6 36689040 ↗Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate
  • T6 39199317 ↗The Physiological Impact of Melatonin, Its Effect on the Course of Diseases and Their Therapy and th
  • T6 35615417 ↗ERS International Congress 2021: highlights from the Respiratory Clinical Care and Physiology Assemb
  • T6 36008648 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2022)
  • T6 32396683 ↗The SARS-CoV-2/COVID-19 pandemic and challenges in stroke care in India
  • T6 36362782 ↗Psychological and Cognitive Effects of Long COVID: A Narrative Review Focusing on the Assessment and
  • T6 38123233 ↗Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review
  • T6 36690948 ↗Association between long COVID, functional activity, and health-related quality of life in older adu
Concordant Care Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
Controls
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
24 sources
  • T1 NCT04718506 ↗Rehabilitation for Post-COVID-19 Syndrome Through a Supervised Exercise Intervention
  • T6INDIRECT 34973396 ↗Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis
  • T6INDIRECT 35429399 ↗Global Prevalence of Post-Coronavirus Disease 2019 (COVID-19) Condition or Long COVID: A Meta-Analys
  • T6INDIRECT 36215063 ↗Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symp
  • T6INDIRECT 36951832 ↗Risk Factors Associated With Post-COVID-19 Condition: A Systematic Review and Meta-analysis
  • T6INDIRECT 33760236 ↗Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 35121209 ↗Mid and long-term neurological and neuropsychiatric manifestations of post-COVID-19 syndrome: A meta
  • T6INDIRECT 33661992 ↗Population risk factors for severe disease and mortality in COVID-19: A global systematic review and
  • T6INDIRECT 34167876 ↗Prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: A syst
  • T6INDIRECT 35739136 ↗Long-COVID in children and adolescents: a systematic review and meta-analyses
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34687662 ↗The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future
  • T6 38433280 ↗NF-κB in biology and targeted therapy: new insights and translational implications
  • T6 36050306 ↗Lactate metabolism in human health and disease
  • T6 35927511 ↗The roles of extracellular vesicles in the immune system
  • T6 32526206 ↗SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract
  • T6 37165196 ↗Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
  • T6 35132265 ↗Long-term cardiovascular outcomes of COVID-19
  • T6 33181098 ↗Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies o
  • T6 33431578 ↗Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients
Cycling
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
28 sources
  • T1 NCT07454395 ↗Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chroni
  • T6INDIRECT 33760236 ↗Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T6INDIRECT 35866452 ↗Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6INDIRECT 33284353 ↗Rehabilitation setting during and after Covid-19: An overview on recommendations
  • T6INDIRECT 33637294 ↗Rehabilitation to enable recovery from COVID-19: a rapid systematic review
  • T6INDIRECT 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 38573638 ↗Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition: A Randomized
  • T6INDIRECT 34591653 ↗Immune signatures underlying post-acute COVID-19 lung sequelae
  • T6 22896693 ↗The pancreas cancer microenvironment
  • T6 37165196 ↗Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
  • T6 33431578 ↗Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients
  • T6INDIRECT 34687662 ↗The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future
  • T6INDIRECT 34997689 ↗Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19
  • T6INDIRECT 37748514 ↗Distinguishing features of long COVID identified through immune profiling
  • T6INDIRECT 35307156 ↗2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocard
  • T6INDIRECT 38123343 ↗Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Dise
  • T6INDIRECT 33251093 ↗Impact of the COVID-19 pandemic on travel behavior in Istanbul: A panel data analysis
  • T6 24661096 ↗Protein design: toward functional metalloenzymes
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 36701528 ↗Spin Hyperpolarization in Modern Magnetic Resonance
  • T6 35216672 ↗Multiple early factors anticipate post-acute COVID-19 sequelae
  • T6 35434682 ↗Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal in
  • T6 35216673 ↗A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
  • T6 37977174 ↗The 2023 report of the Lancet Countdown on health and climate change: the imperative for a health-ce
  • T6 33243837 ↗Autonomic dysfunction in 'long COVID': rationale, physiology and management strategies
  • T6 33288662 ↗IgA dominates the early neutralizing antibody response to SARS-CoV-2
DAOIB
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
2 sources
  • T1REGISTERED-ONLY NCT05764538 ↗DAOIB for the Treatment of Brain Fog
  • T6 38711990 ↗Management of cognitive impairment associated with post-COVID-19 syndrome: recommendations for prima
DMSO-based otic solution with betahistine, dexamethasone, and lidocaine
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT07567274 ↗DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury
DMSO-based transdermal cream with levocarnitine and N-acetylcysteine
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT07567274 ↗DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury
Delayed AIM Question and Answer sessions
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05057676 ↗Autoimmune Intervention Mastery Course Study
Delayed Autoimmune Intervention Mastery Course
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05057676 ↗Autoimmune Intervention Mastery Course Study
Dietary and Lifestyle Recommendations
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT07627815 ↗Evaluating the Safety and Efficacy of PNMR as Treatment for Long COVID
  • T6 38912070 ↗Telemedicine in Cardiology: Enhancing Access to Care and Improving Patient Outcomes
  • T6 PMC11470995 ↗UEG Week 2024 Poster Presentations
Digital Physiotherapy Practice
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
6 sources
  • T1 NCT04742946 ↗Digital Physiotherapy Practice in Long Covid-19 Patients
  • T1 35954922 ↗The Effectiveness of a Four-Week Digital Physiotherapy Intervention to Improve Functional Capacity a
  • T6 37444803 ↗Effectiveness of Digital Physiotherapy Practice Compared to Usual Care in Long COVID Patients: A Sys
  • T6 37754586 ↗Telerehabilitation in Low-Resource Settings to Improve Postural Balance in Older Adults: A Non-Infer
  • T6 38590093 ↗Experiences of people with Long Covid with a digital physiotherapy intervention: A qualitative study
  • T6 40422292 ↗Telerehabilitation as an innovative strategy for the management of anxiety and dyspnea in post-COVID
Dual Task exercise
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
6 sources
  • T1REGISTERED-ONLY NCT07254377 ↗Design and Validation of Innovative Strategies Based on Dual-Task Approach
  • T6 33786571 ↗Community-Based Peer-Led Intervention for Healthy Ageing and Evaluation of the 'HAPPY' Program
  • T6 35294921 ↗The Acceptability of Digital Technology and Tele-Exercise in the Age of COVID-19: Cross-sectional St
  • T6 32510123 ↗Letter to the Editor: The Role of a Geriatrician Has Become Even More Important in an Academic Insti
  • T6 40929575 ↗Cycling-Based Telerehabilitation: Acceptability and Feasibility Study
  • T6 PMC12755232 ↗Full GSA 2025 Abstract Book PDF
Dynamic neural retraining system
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT06933173 ↗RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
  • T6 36982194 ↗Towards a Better Understanding of the Complexities of Myalgic Encephalomyelitis/Chronic Fatigue Synd
  • T6INDIRECT 38792737 ↗Combining Double-Dose and High-Dose Pulsed Dapsone Combination Therapy for Chronic Lyme Disease/Post
Echinochrome A
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
7 sources
  • T1 NCT05531019 ↗COVID-19 Sequelae: Treatment and Monitoring. A Dietary Supplement Based on Sea Urchin Eggs With Echi
  • T6 38282092 ↗Marine natural products and human immunity: novel biomedical resources for anti-infection of SARS-Co
  • T6 40722944 ↗Post-COVID Condition and Neuroinflammation: Possible Management with Antioxidants
  • T6 PPR713523 ↗EuroQol-5D-3L in Long Covid Patients After Supplementation with EchA Marine®, a Sea Urchin Eggs Extr
  • T6 PPR670468 ↗EuroQol-5D-3L in Long Covid patients After Supplementation with EchA Marine<sup>®</sup>, a Sea Urchi
  • T6 PPR669788 ↗EuroQol-5D-3L in Long Covid patients After Supplementation with EchA Marine®, a Sea Urchin Eggs Extr
  • T4 PMC6031936 ↗Posters
Education
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
22 sources
  • T1REGISTERED-ONLY NCT06404060 ↗RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
  • T1 NCT06404047 ↗RECOVER-ENERGIZE Platform Protocol
  • T6INDIRECT 34973396 ↗Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis
  • T6INDIRECT 36215063 ↗Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symp
  • T6INDIRECT 36951832 ↗Risk Factors Associated With Post-COVID-19 Condition: A Systematic Review and Meta-analysis
  • T6INDIRECT 33760236 ↗Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 35739136 ↗Long-COVID in children and adolescents: a systematic review and meta-analyses
  • T6INDIRECT 34634250 ↗Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T1 32503818 ↗Medical and Surgical Education Challenges and Innovations in the COVID-19 Era: A Systematic Review
  • T6INDIRECT 34339806 ↗Psychiatric and neuropsychiatric sequelae of COVID-19 - A systematic review
  • T6INDIRECT 34749198 ↗Alcohol and other substance use during the COVID-19 pandemic: A systematic review
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 32201335 ↗Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 35927511 ↗The roles of extracellular vesicles in the immune system
  • T6 39174535 ↗Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strateg
  • T6 33965003 ↗The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
  • T6 34127835 ↗Hypertension-induced cognitive impairment: from pathophysiology to public health
  • T6 35132265 ↗Long-term cardiovascular outcomes of COVID-19
Education Packet Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
Efgartigimod
T1
T1 — RCT in LC/PASC/PACVS
Harm signalWithdrawnLong COVID
15 sources
  • T1HARM NCT05633407 ↗Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS
  • T1WITHDRAWN NCT05918978 ↗Open Label Extension of Efgartigimod in Adults With Post-COVID-19 POTS
  • T6 33802650 ↗In Translation: FcRn across the Therapeutic Spectrum
  • T6 38617189 ↗Structure and function of therapeutic antibodies approved by the US FDA in 2023
  • T6 39736771 ↗Platelet signaling in immune landscape: comprehensive mechanism and clinical therapy
  • T6 39189008 ↗Cardiovascular disease and covid-19: A systematic review
  • T6 37396922 ↗Fighting Post-COVID and ME/CFS - development of curative therapies
  • T5 39820999 ↗Efgartigimod treatment for therapy-refractory autoimmune encephalitis with coexistent NMDAR and LGI1
  • T6INDIRECT 38390594 ↗Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome?
  • T6INDIRECT 37204997 ↗Postural Orthostatic Tachycardia Syndrome in COVID-19: A Contemporary Review of Mechanisms, Clinical
  • T6INDIRECT 36140251 ↗Autoantibodies as Biomarker and Therapeutic Target in Systemic Sclerosis
  • T6INDIRECT 40156757 ↗Targeting the Neonatal Fc Receptor in Autoimmune Diseases: Pipeline and Progress
  • T6INDIRECT 41089328 ↗Immunotherapies for postural orthostatic tachycardia syndrome, other common autonomic disorders, and
  • T6INDIRECT 37614956 ↗Targeting type 2 inflammation in bullous pemphigoid: current and emerging therapeutic approaches
  • T6 39684504 ↗Advancing Therapeutic and Vaccine Proteins: Switching from Recombinant to Ribosomal Delivery-A Human
Ensitrelvir
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
23 sources
  • T1REGISTERED-ONLY NCT06161688 ↗Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID
  • T6INDIRECT 38314855 ↗Favipiravir for treating COVID-19
  • T1 38972603 ↗Prevention of post COVID-19 condition by early treatment with ensitrelvir in the phase 3 SCORPIO-SR
  • T1 39960062 ↗Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19: Results from the SCORPIO-HR,
  • T1 38890511 ↗Efficacy and Safety of Ensitrelvir for Asymptomatic or Mild COVID-19: An Exploratory Analysis of a M
  • T6INDIRECT 38197702 ↗SARS-CoV-2 viral dynamics in a placebo-controlled phase 2 study of patients infected with the SARS-C
  • T6INDIRECT 40222976 ↗Meplazumab, a CD147 antibody, for severe COVID-19: a double-blind, randomized, placebo-controlled, p
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 37173515 ↗Accelerating antiviral drug discovery: lessons from COVID-19
  • T6 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6HARM 37897341 ↗The IUPHAR/BPS Guide to PHARMACOLOGY in 2024
  • T5 38333218 ↗Case report: Ensitrelvir for treatment of persistent COVID-19 in lymphoma patients: a report of two
  • T6INDIRECT 36603694 ↗Nirmatrelvir and COVID-19: development, pharmacokinetics, clinical efficacy, resistance, relapse, an
  • T6INDIRECT 39897928 ↗SARS-CoV-2 drug resistance and therapeutic approaches
  • T6INDIRECT 39536116 ↗Translating insights into therapies for Long Covid
  • T6INDIRECT 38633552 ↗COVID-19: An Update on Epidemiology, Prevention and Treatment, September-2023
  • T6INDIRECT 39379249 ↗The winding road: Infectious disease considerations for CAR-T and other novel adoptive cellular ther
  • T6INDIRECT 39132824 ↗Persistence of an Infectious Form of SARS-CoV-2 After Protease Inhibitor Treatment of Permissive Cel
  • T6 37112923 ↗Evolution of SARS-CoV-2 Variants: Implications on Immune Escape, Vaccination, Therapeutic and Diagno
  • T6 39947217 ↗Targeting the SARS-CoV-2 reservoir in long COVID
  • T6 38771027 ↗COVID-19 therapeutics
  • T6 36510683 ↗Insights for COVID-19 in 2023
Evidence-Based Informational Support
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06871293 ↗Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19
Exercise
T1
T1 — RCT in LC/PASC/PACVS
RegisteredWithdrawnLong COVIDME/CFS
46 sources
  • T1 NCT04718506 ↗Rehabilitation for Post-COVID-19 Syndrome Through a Supervised Exercise Intervention
  • T1REGISTERED-ONLY NCT05566483 ↗Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and
  • T1 NCT04841759 ↗The Effects of a Multi-factorial Rehabilitation Program for Healthcare Workers Suffering From Post-C
  • T2 NCT04378634 ↗Epigenetics of Post-exertional Malaise in Patients With ME/CFS
  • T6WITHDRAWN NCT06065033 ↗Exercise Interventions in Post-acute Sequelae of Covid-19
  • T6INDIRECT 34373540 ↗More than 50 long-term effects of COVID-19: a systematic review and meta-analysis
  • T6INDIRECT 33760236 ↗Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 35739136 ↗Long-COVID in children and adolescents: a systematic review and meta-analyses
  • T1 36731907 ↗Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regres
  • T6INDIRECT 34643720 ↗Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T6INDIRECT 34580069 ↗Characterising long COVID: a living systematic review
  • T6INDIRECT 32503818 ↗Medical and Surgical Education Challenges and Innovations in the COVID-19 Era: A Systematic Review
  • T6INDIRECT 34339806 ↗Psychiatric and neuropsychiatric sequelae of COVID-19 - A systematic review
  • T6INDIRECT 34268556 ↗Post-acute and long-COVID-19 symptoms in patients with mild diseases: a systematic review
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 33753937 ↗Post-acute COVID-19 syndrome
  • T6INDIRECT 32437679 ↗Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a syst
  • T6INDIRECT 28089638 ↗The effects of acute psychological stress on circulating and stimulated inflammatory markers: A syst
  • T6INDIRECT 22018588 ↗Validity of the International Physical Activity Questionnaire Short Form (IPAQ-SF): a systematic rev
  • T6INDIRECT 18287602 ↗Surgical versus nonsurgical therapy for lumbar spinal stenosis
  • T6INDIRECT 17119140 ↗Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research T
  • T2 21334061 ↗Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and spe
  • T6INDIRECT 17119141 ↗Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research T
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6 18923511 ↗The molecular neurobiology of depression
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34687662 ↗The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future
  • T6 33497610 ↗Adaptive immunity to SARS-CoV-2 and COVID-19
  • T6 38433280 ↗NF-κB in biology and targeted therapy: new insights and translational implications
  • T6 36050306 ↗Lactate metabolism in human health and disease
  • T6 35304603 ↗Exerkines in health, resilience and disease
  • T6 34248921 ↗Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Con
  • T6 34308300 ↗Characterizing long COVID in an international cohort: 7 months of symptoms and their impact
  • T6INDIRECT 29016840 ↗2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atr
  • T6INDIRECT 19375665 ↗Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity
  • T6INDIRECT 19713422 ↗Guidelines for the diagnosis and management of syncope (version 2009)
  • T6INDIRECT 25266247 ↗Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task fo
  • T6 23798298 ↗Lack of exercise is a major cause of chronic diseases
  • T6 17493201 ↗Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept
  • T6 20201874 ↗Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disea
  • T6 29884281 ↗Interoception and Mental Health: A Roadmap
  • T6 30496104 ↗Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseas
  • T6 23459093 ↗The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses
Exercise Therapy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
27 sources
  • T1REGISTERED-ONLY NCT06042751 ↗Psychosomatic, Physical Activity or Both for Post-covid19 Syndrom
  • T1 36731907 ↗Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regres
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T6INDIRECT 37725376 ↗Rehabilitation Interventions for Physical Capacity and Quality of Life in Adults With Post-COVID-19
  • T1 37586104 ↗Effect of Physical Exercise-Based Rehabilitation on Long COVID: A Systematic Review and Meta-analysi
  • T1 35908659 ↗Effect of Pulmonary Rehabilitation Approaches on Dyspnea, Exercise Capacity, Fatigue, Lung Functions
  • T6INDIRECT 36323418 ↗Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and me
  • T6INDIRECT 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T6INDIRECT 33637294 ↗Rehabilitation to enable recovery from COVID-19: a rapid systematic review
  • T1 36111386 ↗Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: A randomized
  • T1 38573638 ↗Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition: A Randomized
  • T6INDIRECT 35079817 ↗Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6INDIRECT 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6INDIRECT 34997689 ↗Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19
  • T6INDIRECT 34682909 ↗Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): An Overview
  • T6INDIRECT 35853576 ↗Postural orthostatic tachycardia syndrome as a sequela of COVID-19
  • T6INDIRECT 34265539 ↗Preparing for the long-haul: Autonomic complications of COVID-19
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6 36043493 ↗The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid
  • T6 38887284 ↗Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: the biology of a neglected disease
  • T6 37475124 ↗Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness
  • T6 33677650 ↗Is postural orthostatic tachycardia syndrome (POTS) a central nervous system disorder?
  • T6 32455961 ↗Potential Application of Whole Body Vibration Exercise For Improving The Clinical Conditions of COVI
  • T6 37795783 ↗Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood
  • T6 37080828 ↗Long COVID: pathophysiological factors and abnormalities of coagulation
Experimental group
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
22 sources
  • T1 NCT05289128 ↗EEG as Predictor of HD-tDCS Effectiveness in Long COVID-19
  • T6INDIRECT 33781283 ↗Mental burden and its risk and protective factors during the early phase of the SARS-CoV-2 pandemic:
  • T6INDIRECT 33871065 ↗Digital interventions for the management of chronic obstructive pulmonary disease
  • T6INDIRECT 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 35414491 ↗Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-
  • T6INDIRECT 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6INDIRECT 36111386 ↗Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: A randomized
  • T6INDIRECT 36191860 ↗Home-based respiratory muscle training on quality of life and exercise tolerance in long-term post-C
  • T6INDIRECT 35489367 ↗An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms follow
  • T6INDIRECT 35450527 ↗Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combined with Olfactory Training to Tr
  • T6 37848036 ↗Serotonin reduction in post-acute sequelae of viral infection
  • T6INDIRECT 37365191 ↗Neuropsychological deficits in patients with persistent COVID-19 symptoms: a systematic review and m
  • T6INDIRECT 33520961 ↗A Review on Modifications of Amniotic Membrane for Biomedical Applications
  • T6INDIRECT 34123972 ↗Coronavirus Disease 2019 in Children
  • T6INDIRECT 37695464 ↗Virtual and augmented reality in intensive care medicine: a systematic review
  • T6INDIRECT 36458984 ↗Brain functional connectivity alterations associated with neuropsychological performance 6-9 months
  • T6 34133077 ↗Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-1
  • T6 34624208 ↗Role of miR-2392 in driving SARS-CoV-2 infection
  • T6 39198643 ↗Fibrin drives thromboinflammation and neuropathology in COVID-19
  • T6 31121312 ↗The inclusion of zinc into mineralized collagen scaffolds for craniofacial bone repair applications
  • T6 37919524 ↗SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells
Experimental group/ Active HD-tDCS
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05289115 ↗Protocol for Assistance to Patients With Long Covid-19 Undergoing Treatment With HD-tDCS
Experimental: Paxlovid 15 day dosing
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05595369 ↗RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptom
Experimental: Paxlovid 25 day dosing
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05595369 ↗RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptom
Extension for Community Healthcare Outcomes
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
23 sources
  • T1REGISTERED-ONLY NCT05167227 ↗Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID
  • T6INDIRECT 39856560 ↗Ten pressure points in primary care during COVID-19: findings from an international narrative review
  • T6 36063284 ↗HIV Care Meets Telehealth: a Review of Successes, Disparities, and Unresolved Challenges
  • T6 38145115 ↗Pandemic telehealth flexibilities for buprenorphine treatment: a synthesis of evidence and policy im
  • T6 34511221 ↗Telemedicine and current clinical practice trends in the COVID-19 pandemic
  • T6 32535870 ↗Surgical Oncologists and the COVID-19 Pandemic: Guiding Cancer Patients Effectively through Turbulen
  • T6 36194041 ↗Appropriate Use of Telehealth Visits in Endocrinology: Policy Perspective of the Endocrine Society
  • T6 37573421 ↗A technology-enabled multi-disciplinary team-based care model for the management of Long COVID and o
  • T6INDIRECT 38093376 ↗Professional care workforce: a rapid review of evidence supporting methods of recruitment, retention
  • T6INDIRECT 36082018 ↗Using Peer Power to Reduce Health Disparities: Implementation of a Diabetes Support Coach Program in
  • T6INDIRECT 34297318 ↗Abstracts from the 2021 Annual Meeting of the Society of General Internal Medicine
  • T6INDIRECT 35669936 ↗Postacute Sequelae of SARS-CoV-2 Infection-Lessons Learned From a Coordinated Health System Response
  • T6INDIRECT 36714541 ↗Implementation and impacts of virtual team-based care planning for older persons in formal care sett
  • T6INDIRECT 37577254 ↗Mentoring approaches in a safe surgery program in Tanzania: Lessons learned during COVID-19 and reco
  • T6INDIRECT 37265709 ↗Connecting Behavioral Health Specialists With Schools: Adapting a Telementoring Series During COVID-
  • T6 35572020 ↗Canadian Conference on Medical Education 2022 abstracts
  • T6 35991483 ↗Annual Meeting of the Canadian Association for the Study of the Liver (CASL), the Canadian Network o
  • T6 34926835 ↗Program Abstracts from The GSA 2021 Annual Scientific Meeting, "Disruption to Transformation: Aging
  • T6 40986224 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2025)
  • T6 PMC8105566 ↗Canadian Conference on Medical Education 2021 Abstracts Les résumés de la Conférence canadienne sur
  • T6 PMC12755232 ↗Full GSA 2025 Abstract Book PDF
  • T6 34066829 ↗A Narrative Review of Factors Historically Influencing Telehealth Use across Six Medical Specialties
  • T6 38449917 ↗Burnout, Compassion Fatigue, and the Long Haul of Caring for Long COVID
Flavonoids
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
24 sources
  • T1 NCT06064838 ↗Effects of Cacao Flavonoids in Long COVID-19 Patients (FLALOC)
  • T6INDIRECT 35455977 ↗Systematic Review of the Common Pathophysiological Mechanisms in COVID-19 and Neurodegeneration: The
  • T6INDIRECT 36204816 ↗Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review
  • T6INDIRECT 36035707 ↗Mainstreaming orphan millets for advancing climate smart agriculture to secure nutrition and health
  • T6INDIRECT 36439263 ↗Cys-loop receptors on cannabinoids: All high?
  • T6INDIRECT 40822451 ↗Exploring the clinical effects of &lt;i&gt;Andrographis paniculata&lt;/i&gt;-derived compounds, its
  • T6INDIRECT 36505757 ↗The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19
  • T6INDIRECT 37891178 ↗Standardized Brazilian green propolis extract (EPP-AF®) in COVID-19 outcomes: a randomized double-bl
  • T6INDIRECT 39940991 ↗Mitochondria-Derived Vesicles and Inflammatory Profiles of Adults with Long COVID Supplemented with
  • T6INDIRECT 35276467 ↗Efficacy of a multiple-indication antiviral herbal drug (Saliravira®) for COVID-19 outpatients: A pr
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 35566252 ↗Flavonoids as Potential Anti-Inflammatory Molecules: A Review
  • T6INDIRECT 38378653 ↗Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatme
  • T6INDIRECT 36364899 ↗A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
  • T6INDIRECT 32455612 ↗Novel Coronavirus (COVID-19) and Dentistry-A Comprehensive Review of Literature
  • T6INDIRECT 36464706 ↗Small molecules in the treatment of COVID-19
  • T6INDIRECT 37298527 ↗Neurodegenerative and Neurodevelopmental Diseases and the Gut-Brain Axis: The Potential of Therapeut
  • T6INDIRECT 33421734 ↗The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacol
  • T6 37359549 ↗The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to
  • T6 21526386 ↗Engineering microbial factories for synthesis of value-added products
  • T6 36198912 ↗COVID-19 and cellular senescence
  • T6 35874958 ↗Long COVID and its Management
  • T6 33847020 ↗Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue
Follow Up Phone Calls
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
43 sources
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
  • T2REGISTERED-ONLY NCT07523113 ↗ME/CFS Brain Fog: Cognitive Rehabilitation Trial
  • T6INDIRECT 37299488 ↗Effectiveness of Lifestyle Nutrition and Physical Activity Interventions for Childhood Obesity and A
  • T6INDIRECT 38847297 ↗Integrated care models for youth mental health: A systematic review and meta-analysis
  • T6INDIRECT 35902951 ↗Impact of the COVID-19 pandemic on suicidal attempts and death rates: a systematic review
  • T6INDIRECT 34857029 ↗Clinical and cost-effectiveness of a New psychosocial intervention to support Independence in Dement
  • T6INDIRECT 36056378 ↗Research interrupted: applying the CONSERVE 2021 Statement to a randomized trial of rehabilitation d
  • T6INDIRECT 37739466 ↗Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: a double-blin
  • T1 38312212 ↗Pulmonary Function and Survival 1 Year After Dupilumab Treatment of Acute Moderate to Severe Coronav
  • T6 34162913 ↗Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients
  • T6 34874962 ↗Prevalence and predictors of Post-Acute COVID-19 Syndrome (PACS) after hospital discharge: A cohort
  • T6 36512382 ↗'I don't know what to do or where to go'. Experiences of accessing healthcare support from the persp
  • T6 34861604 ↗Long term predictors of breathlessness, exercise intolerance, chronic fatigue and well-being in hosp
  • T6 38580370 ↗Personalised Exercise-Rehabilitation FOR people with Multiple long-term conditions (PERFORM): protoc
  • T6INDIRECT 29376559 ↗Physical activity for women with breast cancer after adjuvant therapy
  • T6INDIRECT 27883365 ↗Educational interventions for the management of cancer-related fatigue in adults
  • T6INDIRECT 34532852 ↗Cannabinoids for the treatment of dementia
  • T6INDIRECT 28854852 ↗Effects of Self-Management Interventions in Patients With Irritable Bowel Syndrome: Systematic Revie
  • T6INDIRECT 28931531 ↗Clinical and cost-effectiveness of the Lightning Process in addition to specialist medical care for
  • T6INDIRECT 26179651 ↗Assessing Cognitive behavioural Therapy in Irritable Bowel (ACTIB): protocol for a randomised contro
  • T6INDIRECT 24304689 ↗The feasibility and acceptability of conducting a trial of specialist medical care and the Lightning
  • T6INDIRECT 35671133 ↗Reframe the pain: Divided attention and positive memory reframing to reduce needle pain and distress
  • T6INDIRECT 24315246 ↗Early experience with a brief, multimodal, multidisciplinary treatment program for fibromyalgia
  • T6 35940683 ↗Optimal Emergency Department Care Practices for Persons Living With Dementia: A Scoping Review
  • T6INDIRECT 33653852 ↗Treatment of unexplained coma and hypokinetic-rigid syndrome in a patient with COVID-19
  • T6INDIRECT 33313986 ↗ESICM LIVES 2020
  • T6INDIRECT 35859555 ↗Immediate and short-term prevalence of depression in covid-19 patients and its correlation with cont
  • T6 35747260 ↗Cost and Satisfaction Implications of Using Telehealth for Plagiocephaly
  • T6 38350825 ↗Fourth Controlled Human Infection Model (CHIM) meeting - CHIMs in endemic countries, May 22-23, 2023
  • T6 40542608 ↗Special Issue: Abstracts of the 11&lt;sup&gt;th&lt;/sup&gt; Congress of the European Academy of Neur
  • T6 41386990 ↗Canadian Spine Society: 25th Annual Scientific Conference, February 25 to 28, 2025, Fairmont Le Mano
  • T6 35122083 ↗Editorial: Post Acute Care for Frail Older Persons: Time for a Standardized Model of Care
  • T6 PMC13111897 ↗2026 International Congress Abstract Supplement
  • T6 34551007 ↗SARS-CoV-2 pneumonia follow-up and long COVID in primary care: A retrospective observational study i
  • T6INDIRECT 29196279 ↗Using mHealth Technology in a Self-Management Intervention to Promote Physical Activity Among Adults
  • T6INDIRECT 25869016 ↗Abstracts from the 38th annual meeting of the society of general internal medicine
  • T6INDIRECT 32725471 ↗Abstracts from the 2020 Annual Meeting of the Society of General Internal Medicine
  • T6INDIRECT 36365042 ↗The Troublesome Ticks Research Protocol: Developing a Comprehensive, Multidiscipline Research Plan f
  • T6INDIRECT 30480124 ↗Program Abstracts from the 21st International Association of Gerontology and Geriatrics (IAGG) World
  • T6 28156288 ↗Proceedings of the 15th International Congress on Circumpolar Health
  • T6 24085684 ↗Abstracts of the 2013 Annual Meeting of the American College of Rheumatology. October 25-30, 2013. S
  • T6 36832443 ↗Developmental Pathway Choices of Young People Presenting to a Gender Service with Gender Distress: A
  • T6 36471349 ↗Personalised rehabilitation to improve return to work in patients with persistent spinal pain syndro
Freeze Dried Potato Starch Capsule
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05227170 ↗Impact of Lp299v on Vascular Function in Patients With PASC
Functional and cognitive rehabilitation strategy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06871293 ↗Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19
HB-adMSCs
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
16 sources
  • T1 NCT05126563 ↗Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVI
  • T6INDIRECT 35782071 ↗Association between Mesenchymal Stem Cells and COVID-19 Therapy: Systematic Review and Current Trend
  • T6 35187617 ↗Mesenchymal stem cell-based treatments for COVID-19: status and future perspectives for clinical app
  • T6 35897770 ↗Immunomodulation of Mesenchymal Stem Cells in Acute Lung Injury: From Preclinical Animal Models to T
  • T6 39144566 ↗Emerging Landscape of Mesenchymal Stem Cell Senescence Mechanisms and Implications on Therapeutic St
  • T6 36600055 ↗Critical roles of cytokine storm and bacterial infection in patients with COVID-19: therapeutic pote
  • T6 37395459 ↗Mechanisms of Potential Therapeutic Utilization of Mesenchymal Stem Cells in COVID-19 Treatment
  • T6INDIRECT 38005826 ↗Immune-Cell-Based Therapy for COVID-19: Current Status
  • T6INDIRECT 41235241 ↗Therapeutic challenges in central nervous system viral infections: advancing mesenchymal stem cell-b
  • T6INDIRECT 35426198 ↗Stem Cell-based therapies for COVID-19-related acute respiratory distress syndrome
  • T6INDIRECT 42325370 ↗Viral persistence in long COVID: Research advances and treatment strategies
  • T6INDIRECT 42024210 ↗Abstracts Presented at the 32nd Annual Conference of the International Society for Quality of Life R
  • T4 PMC11245638 ↗ISEV2024 Abstract Book
  • T4 PMC9662107 ↗46th Annual Conference of AOMSI
  • T6 34831101 ↗Molecular Mechanisms of Multi-Organ Failure in COVID-19 and Potential of Stem Cell Therapy
  • T6 35174448 ↗Stem cell therapy for COVID-19 pneumonia
HOBSCOTCH-PACS
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06391489 ↗HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)
Health Education
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
26 sources
  • T1REGISTERED-ONLY NCT05890599 ↗Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19
  • T6INDIRECT 36731907 ↗Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regres
  • T6INDIRECT 34807630 ↗Changes in alcohol use during COVID-19 and associations with contextual and individual difference va
  • T6INDIRECT 33766163 ↗Prevalence of depressive symptoms among Chinese university students amid the COVID-19 pandemic: a sy
  • T6INDIRECT 33871065 ↗Digital interventions for the management of chronic obstructive pulmonary disease
  • T1 36634261 ↗The Usability, Feasibility, Acceptability, and Efficacy of Digital Mental Health Services in the COV
  • T6INDIRECT 36978166 ↗Ethnic minority representation in UK COVID-19 trials: systematic review and meta-analysis
  • T6INDIRECT 37391766 ↗Growing old in China in socioeconomic and epidemiological context: systematic review of social care
  • T6INDIRECT 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T1 34693988 ↗Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pu
  • T6INDIRECT 32454187 ↗Review of trials currently testing treatment and prevention of COVID-19
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T4 35390342 ↗The Lancet Global Health Commission on financing primary health care: putting people at the centre
  • T4 34315427 ↗COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID
  • T4 32685700 ↗Germany's digital health reforms in the COVID-19 era: lessons and opportunities for other countries
  • T6INDIRECT 32745693 ↗Managing cancer patients during the COVID-19 pandemic: an ESMO multidisciplinary expert consensus
  • T6INDIRECT 38123343 ↗Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Dise
  • T4 35331261 ↗Health care workers' experiences during the COVID-19 pandemic: a scoping review
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 39419055 ↗Global health 2050: the path to halving premature death by mid-century
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
  • T6 36115368 ↗The Lancet Commission on lessons for the future from the COVID-19 pandemic
  • T6 32760367 ↗Impact of Vaccines; Health, Economic and Social Perspectives
  • T6 37777291 ↗The need to promote sleep health in public health agendas across the globe
  • T6 35338841 ↗The intersecting pandemics of tuberculosis and COVID-19: population-level and patient-level impact,
Heat therapy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
17 sources
  • T1REGISTERED-ONLY NCT06928116 ↗Heat thErapy And mobiLity in COVID-19 Survivors
  • T6 38231996 ↗Recent Advances in Micro- and Nano-Drug Delivery Systems Based on Natural and Synthetic Biomaterials
  • T6 36376534 ↗Updates on the Diagnosis and Treatment of Peripheral Autonomic Neuropathies
  • T6 38813611 ↗Socioeconomic status as a potential mediator of arterial aging in marginalized ethnic and racial gro
  • T6 39379918 ↗Sex-specific differences of cardiopulmonary fitness and pulmonary function in exercise-based rehabil
  • T6 32840677 ↗56<sup>th</sup> EASD Annual Meeting of the European Association for the Study of Diabetes : 21-25 Se
  • T6INDIRECT 36412591 ↗A Multimodal Approach in the Treatment of Persistent Post-COVID
  • T6INDIRECT 37366663 ↗Treatments of COVID-19-Associated Taste and Saliva Secretory Disorders
  • T6INDIRECT 36008648 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2022)
  • T6INDIRECT 36467817 ↗COVID-19 infection and pain in adolescents with sickle cell disease: A case series
  • T6INDIRECT 41091675 ↗Return-to-work for people living with long COVID: A scoping review of interventions and recommendati
  • T6INDIRECT 40986224 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2025)
  • T6 41598223 ↗Sarcopenia as a Multisystem Disorder-Connections with Neural and Cardiovascular Systems-A Related PR
  • T6 42293373 ↗Thermal stress: an untapped potential in rehabilitation? An opinion paper on Finnish sauna and whole
  • T6 36972259 ↗Influence of high-energy laser therapy to the patellar tendon on its ligamentous microcirculation: A
  • T6 40724716 ↗Healthcare Interventions in the Management of Rheumatic Diseases: A Narrative Analysis of Effectiven
  • T6 37190098 ↗A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages
Hi-Ox device
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06928506 ↗Effect of Hi-OxSR for the Treatment of Post COVID Condition
Hi-OxSR device
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06928506 ↗Effect of Hi-OxSR for the Treatment of Post COVID Condition
Home-based physical training
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
3 sources
  • T1 NCT05360563 ↗Home-based Exercise Program in Patients With the Post-COVID-19 Condition
  • T6 37288400 ↗Impact of Covid-19 lockdown on sleep quality, physical activity, and body weight among university st
  • T6 40423283 ↗Return-to-Play Timeline and Recovery Predictors After COVID-19 Infection in Elite Football Players
Hydroxy gas
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06159296 ↗Effect of Inhaled Hydroxy Gas on Long COVID Symptoms
IVIG + Coordinated Care
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT06305780 ↗RECOVER-AUTONOMIC Platform Protocol
  • T6 PMC12982061 ↗Candidate treatments for long COVID: a narrative review of expert and patient-driven priorities
Ibudilast
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
13 sources
  • T1 NCT05513560 ↗RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine
  • T6INDIRECT 39446164 ↗Pentoxifylline in COVID-19 and considerations for its research in long COVID
  • T6INDIRECT 38783390 ↗Efficacy of intrathecal mesenchymal stem cell-neural progenitor therapy in progressive MS: results f
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 33240091 ↗Challenges for Drug Repurposing in the COVID-19 Pandemic Era
  • T6 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6HARM 33421734 ↗The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacol
  • T6 37396922 ↗Fighting Post-COVID and ME/CFS - development of curative therapies
  • T6INDIRECT 39536116 ↗Translating insights into therapies for Long Covid
  • T6INDIRECT 39599909 ↗Beyond Antivirals: Alternative Therapies for Long COVID
  • T4 PMC11627187 ↗ACNP 63rd Annual Meeting: Poster Abstracts P305-P608
  • T6 38611624 ↗Long COVID: Long-Term Impact of SARS-CoV2
  • T6 38622939 ↗Review of COVID-19 Therapeutics by Mechanism: From Discovery to Approval
IgPro20
T1
T1 — RCT in LC/PASC/PACVS
WithdrawnLong COVID
2 sources
  • T1WITHDRAWN NCT06524739 ↗Double-blind, Randomized, Placebo-controlled Study Evaluating Efficacy and Safety of IgPro20 in Post
  • T6 41089328 ↗Immunotherapies for postural orthostatic tachycardia syndrome, other common autonomic disorders, and
Immediate Autoimmune Intervention Mastery Course
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05057676 ↗Autoimmune Intervention Mastery Course Study
Immediate Question and Answer sessions.
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05057676 ↗Autoimmune Intervention Mastery Course Study
Immulina TM
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05524532 ↗Effects of Immulina TM Supplements With PASC Patients
Immunoadsorption
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
24 sources
  • T1 NCT05710770 ↗Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS
  • T6INDIRECT 38459000 ↗Possible temporal relationship between SARS-CoV-2 infection and anti-NMDA receptor encephalitis: a m
  • T6INDIRECT 39994269 ↗Plasma exchange therapy for the post COVID-19 condition: a phase II, double-blind, placebo-controlle
  • T1 36719401 ↗Immunoadsorption to treat patients with severe post-COVID syndrome
  • T6 38534355 ↗Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders
  • T6 33880442 ↗Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID
  • T6 33668514 ↗Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestatio
  • T6 37662515 ↗Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: result
  • T6 35806214 ↗Long COVID: Association of Functional Autoantibodies against G-Protein-Coupled Receptors with an Imp
  • T6 38454468 ↗IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in
  • T6 40176165 ↗Immunoadsorption study Mainz in adults with post-COVID syndrome (IAMPOCO)-a single-blinded sham-cont
  • T6INDIRECT 37002488 ↗Immunopathogenesis and immunomodulatory therapy for myocarditis
  • T6INDIRECT 39240417 ↗Towards an understanding of physical activity-induced post-exertional malaise: Insights into microva
  • T6INDIRECT 38256459 ↗Advancing Research and Treatment: An Overview of Clinical Trials in Myalgic Encephalomyelitis/Chroni
  • T6INDIRECT 36298623 ↗COVID-19 Vaccine-Associated Optic Neuropathy: A Systematic Review of 45 Patients
  • T6INDIRECT 37007494 ↗Review of therapeutic mechanisms and applications based on SARS-CoV-2 neutralizing antibodies
  • T6INDIRECT 37388279 ↗Long COVID: Complications, Underlying Mechanisms, and Treatment Strategies
  • T6INDIRECT 37396922 ↗Fighting Post-COVID and ME/CFS - development of curative therapies
  • T6 38510714 ↗Diagnostic and Therapeutic Aptamers: A Promising Pathway to Improved Cardiovascular Disease Manageme
  • T6 36431053 ↗A Review Pertaining to SARS-CoV-2 and Autoimmune Diseases: What Is the Connection?
  • T6 39727052 ↗Key Pathophysiological Role of Skeletal Muscle Disturbance in Post COVID and Myalgic Encephalomyelit
  • T6 39351782 ↗Antibodies in neurological diseases: Established, emerging, explorative
  • T6 36140251 ↗Autoantibodies as Biomarker and Therapeutic Target in Systemic Sclerosis
  • T6 34263741 ↗Pathomechanisms and possible interventions in myalgic encephalomyelitis/chronic fatigue syndrome (ME
In-lab Brain Health Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
In-lab Instrumental Activities of Living Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
Inspiratory muscle training
T1
T1 — RCT in LC/PASC/PACVS
Long COVIDME/CFS
41 sources
  • T1 NCT04718506 ↗Rehabilitation for Post-COVID-19 Syndrome Through a Supervised Exercise Intervention
  • T2 NCT05196529 ↗Inspiratory Muscle Training in ME/CFS and COVID-19 Survivors
  • T6 NCT05024474 ↗Effects of Inspiratory Muscle Training After Covid-19 (ReCOV)
  • T6INDIRECT 37725376 ↗Rehabilitation Interventions for Physical Capacity and Quality of Life in Adults With Post-COVID-19
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 35265644 ↗Effect of Pulmonary Rehabilitation for Patients With Post-COVID-19: A Systematic Review and Meta-Ana
  • T1 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6INDIRECT 39603702 ↗Interventions for the management of long covid (post-covid condition): living systematic review
  • T1 35236727 ↗Inspiratory muscle training enhances recovery post-COVID-19: a randomised controlled trial
  • T6INDIRECT 36111386 ↗Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: A randomized
  • T6INDIRECT 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 36191860 ↗Home-based respiratory muscle training on quality of life and exercise tolerance in long-term post-C
  • T6INDIRECT 35409815 ↗Cardiopulmonary Rehabilitation in Long-COVID-19 Patients with Persistent Breathlessness and Fatigue:
  • T6INDIRECT 35203084 ↗Outpatient Pulmonary Rehabilitation in Patients with Long COVID Improves Exercise Capacity, Function
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6INDIRECT 26358158 ↗Exercise therapy for fatigue in multiple sclerosis
  • T6INDIRECT 37651553 ↗Interventions for fatigue in people with kidney failure requiring dialysis
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 38214047 ↗Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation
  • T6INDIRECT 37344767 ↗Clinical effectiveness of rehabilitation in ambulatory care for patients with persisting symptoms af
  • T6INDIRECT 25753362 ↗Protocol for the PREHAB study-Pre-operative Rehabilitation for reduction of Hospitalization After co
  • T6 31092666 ↗PREhabilitation for improving QUality of recovery after ELective cardiac surgery (PREQUEL) study: pr
  • T6INDIRECT 36130789 ↗Effectiveness of home-based pulmonary rehabilitation: systematic review and meta-analysis
  • T6INDIRECT 37193738 ↗Effectiveness of a telerehabilitation intervention using ReCOVery APP of long COVID patients: a rand
  • T6INDIRECT 36560801 ↗Efficacy of Therapeutic Exercise in Reversing Decreased Strength, Impaired Respiratory Function, Dec
  • T6INDIRECT 36198415 ↗The effects of COVID-19 on respiratory muscle performance: making the case for respiratory muscle te
  • T6INDIRECT 33364571 ↗Pulmonary Rehabilitation in COVID-19 patients: A scoping review of current practice and its applicat
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 35416359 ↗Muscle dysfunction in the long coronavirus disease 2019 syndrome: Pathogenesis and clinical approach
  • T6 34066560 ↗Probiotics, Photobiomodulation, and Disease Management: Controversies and Challenges
  • T6 35615417 ↗ERS International Congress 2021: highlights from the Respiratory Clinical Care and Physiology Assemb
  • T6 40724982 ↗Pulmonary Embolism in Acute Ischaemic Stroke: Evolving Evidence, Diagnostic Challenges, and a Novel
  • T6 37099534 ↗Battling the unknown: Using composite vignettes to portray lived experiences of COVID-19 and long-CO
  • T6 37216955 ↗Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical c
  • T6INDIRECT 39010975 ↗Evidence for exercise-based interventions across 45 different long-term conditions: an overview of s
  • T6INDIRECT 34160029 ↗Apparent Discordance Between the Epidemiology of COVID-19 and Recommended Outcomes and Treatments: A
  • T6INDIRECT 39663173 ↗Defining and measuring long COVID fatigue: a scoping review
  • T6INDIRECT 39337079 ↗A Pilot Study on the Effects of Exercise Training on Cardiorespiratory Performance, Quality of Life,
  • T6INDIRECT 34633571 ↗ESICM LIVES 2021: Part 2
  • T6 38999923 ↗The Effect of Physical Activity/Exercise on miRNA Expression and Function in Non-Communicable Diseas
  • T6 8322233 ↗Skeletal muscle metabolism during exercise and recovery in patients with respiratory failure
Ketamine only
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
3 sources
  • T1 NCT06821087 ↗Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
  • T6 38322143 ↗Listening to music during intranasal (es)ketamine therapy in patients with treatment-resistant depre
  • T6 42186575 ↗Early suicidal ideation change and suicidality-associated emergency department utilization after ket
Keytruda
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
12 sources
  • T1REGISTERED-ONLY NCT07388550 ↗Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2
  • T6 32925078 ↗COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications
  • T6 38617189 ↗Structure and function of therapeutic antibodies approved by the US FDA in 2023
  • T6 37894850 ↗A Comparison between SARS-CoV-2 and Gram-Negative Bacteria-Induced Hyperinflammation and Sepsis
  • T6 34784300 ↗PD-1 blockade counteracts post-COVID-19 immune abnormalities and stimulates the anti-SARS-CoV-2 immu
  • T6 34297318 ↗Abstracts from the 2021 Annual Meeting of the Society of General Internal Medicine
  • T6INDIRECT 37290960 ↗EACR 2023: Innovative Cancer Science, 12-15 June 2023, Torino, Italy
  • T4 PMC9421640 ↗21st ISoP Annual Meeting “A New Era of Pharmacovigilance: Challenges and Opportunities” 20–23 Septem
  • T4 PMC11499952 ↗Abstract Book : Topic: 13th International Symposium on Hodgkin Lymphoma; October 2024
  • T4 PMC11177578 ↗EHA2024 Hybrid Congress
  • T6 40733649 ↗Research and Clinical Progress of Therapeutic Tumor Vaccines
  • T6 39684504 ↗Advancing Therapeutic and Vaccine Proteins: Switching from Recombinant to Ribosomal Delivery-A Human
Larazotide Acetate
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
12 sources
  • T1REGISTERED-ONLY NCT05747534 ↗AT1001 for the Treatment of Long COVID
  • T6INDIRECT 39774607 ↗Mucosal immune response in biology, disease prevention and treatment
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 35563874 ↗Obstructive Sleep Apnea as a Risk Factor for COVID-19 Severity-The Gut Microbiome as a Common Player
  • T6 35727635 ↗Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-
  • T6 35868344 ↗Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics
  • T6INDIRECT 36147602 ↗Zonulin, a marker of gut permeability, is associated with mortality in a cohort of hospitalised peru
  • T4 PMC13290681 ↗Abstract
  • T4 PMC11755068 ↗Abstract
  • T4 PMC10627784 ↗APPSPGHAN 2023
  • T6 35887067 ↗Celiac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic
  • T6 41304215 ↗Changes in the Gut Microbiota of Patients After SARS-CoV-2 Infection: What Do We Know?
LingZhi capsule
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06739720 ↗RCT of Efficacy and Safety of CP003 on CFS/ME or Post-COVID Fatigue
Long COVID
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
24 sources
  • T6 37080828 ↗Long COVID: pathophysiological factors and abnormalities of coagulation.
  • T6 35176758 ↗Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations.
  • T1 34373540 ↗More than 50 long-term effects of COVID-19: a systematic review and meta-analysis
  • T1 34973396 ↗Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis
  • T1 35429399 ↗Global Prevalence of Post-Coronavirus Disease 2019 (COVID-19) Condition or Long COVID: A Meta-Analys
  • T1 36215063 ↗Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symp
  • T1 36951832 ↗Risk Factors Associated With Post-COVID-19 Condition: A Systematic Review and Meta-analysis
  • T1 35121209 ↗Mid and long-term neurological and neuropsychiatric manifestations of post-COVID-19 syndrome: A meta
  • T1 34463956 ↗Post-acute COVID-19 syndrome (PCS) and health-related quality of life (HRQoL)-A systematic review an
  • T1 34634250 ↗Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in
  • T6INDIRECT 34643720 ↗Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review
  • T1 34580069 ↗Characterising long COVID: a living systematic review
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T4 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 33497610 ↗Adaptive immunity to SARS-CoV-2 and COVID-19
  • T6 34248921 ↗Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Con
  • T6 35105985 ↗Pathological sequelae of long-haul COVID
  • T6 33743212 ↗COVID-19 and the human innate immune system
  • T6 35216672 ↗Multiple early factors anticipate post-acute COVID-19 sequelae
  • T6 34308300 ↗Characterizing long COVID in an international cohort: 7 months of symptoms and their impact
  • T6 35132265 ↗Long-term cardiovascular outcomes of COVID-19
Long COVID Coping and Recovery Intervention
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05453201 ↗Developing an Integrative, Recovery-Based, Post-Acute COVID-19 Syndrome (PACS) Psychotherapeutic Int
Long COVID or Post-acute Sequelae of COVID
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
27 sources
  • T6 34248921 ↗Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Con
  • T1 40476637 ↗Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of Symptoms 3 Years Post-SARS-
  • T1 41605818 ↗Prevalence of new-onset diabetes following COVID-19 infection: A systematic review and meta-analysis
  • T1 35955740 ↗COVID-19 and the Immune Response: A Multi-Phasic Approach to the Treatment of COVID-19
  • T1 39052056 ↗Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review
  • T1 40075382 ↗Health-related quality of life in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post COVID-
  • T1 36186977 ↗The rationale for the treatment of long-Covid symptoms - A cardiologist's view
  • T1 40084919 ↗The Omics Landscape of Long COVID-A Comprehensive Systematic Review to Advance Biomarker, Target and
  • T6INDIRECT 41869328 ↗Global trends in research of neuroimmune in lung diseases over past decade: a bibliometric analysis
  • T1 38386633 ↗Loss of socioemotional and occupational roles in individuals with Long COVID according to sociodemog
  • T6 37667052 ↗SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
  • T6 34398188 ↗Acute and chronic neurological disorders in COVID-19: potential mechanisms of disease
  • T4 34961785 ↗Neonates and COVID-19: state of the art : Neonatal Sepsis series
  • T4 37179568 ↗Long COVID: Clinical characteristics, proposed pathogenesis and potential therapeutic targets
  • T4 34452459 ↗COVID-19 Convalescent Plasma Is More than Neutralizing Antibodies: A Narrative Review of Potential B
  • T6INDIRECT 37105860 ↗Maternal and neonatal outcomes following SARS-CoV-2 infection
  • T4 36836515 ↗A Systematic Review of Chest Imaging Findings in Long COVID Patients
  • T6INDIRECT 36998202 ↗Viruses and amyloids - a vicious liaison
  • T6INDIRECT 37004544 ↗Direct and indirect impact of SARS-CoV-2 on the brain
  • T6INDIRECT 36169154 ↗Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of aut
  • T6 35215871 ↗The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications
  • T6 36551869 ↗Understanding Long COVID; Mitochondrial Health and Adaptation-Old Pathways, New Problems
  • T6 34801526 ↗The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders
  • T6 37483591 ↗Eosinophils as potential biomarkers in respiratory viral infections
  • T6 35449732 ↗Long COVID: The Nature of Thrombotic Sequelae Determines the Necessity of Early Anticoagulation
  • T6 37064029 ↗A review of cytokine-based pathophysiology of Long COVID symptoms
  • T6 36015078 ↗The Occurrence of Hyperactivated Platelets and Fibrinaloid Microclots in Myalgic Encephalomyelitis/C
Long COVID or post-COVID
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
28 sources
  • T6 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments.
  • T1 36215063 ↗Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symp
  • T1 36951832 ↗Risk Factors Associated With Post-COVID-19 Condition: A Systematic Review and Meta-analysis
  • T1 35739136 ↗Long-COVID in children and adolescents: a systematic review and meta-analyses
  • T1 36990297 ↗COVID-19 vaccination for the prevention and treatment of long COVID: A systematic review and meta-an
  • T1 37084750 ↗Safety and effectiveness of vaccines against COVID-19 in children aged 5-11 years: a systematic revi
  • T1 38965510 ↗Post-COVID syndrome prevalence: a systematic review and meta-analysis
  • T6INDIRECT 34791425 ↗The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the mus
  • T1HARM 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T1 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 38848477 ↗Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection: The S
  • T3 33789877 ↗Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study
  • T4 34163217 ↗The Conundrum of 'Long-COVID-19': A Narrative Review
  • T4 36051247 ↗Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID sympt
  • T4 34386785 ↗Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort
  • T4 34036253 ↗Characteristics and predictors of acute and chronic post-COVID syndrome: A systematic review and met
  • T4 34095290 ↗Benefits of pulmonary rehabilitation in COVID-19: a prospective observational cohort study
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6 34028807 ↗COVID-19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts
  • T6 36851614 ↗Persistent SARS-CoV-2 Infection, EBV, HHV-6 and Other Factors May Contribute to Inflammation and Aut
  • T6 36385449 ↗Neuropsychiatric aspects of long COVID: A comprehensive review
  • T6 36071155 ↗Long Covid: where we stand and challenges ahead
  • T6 37192595 ↗COVID-19, post-acute COVID-19 syndrome (PACS, "long COVID") and post-COVID-19 vaccination syndrome (
  • T6 36210445 ↗Pathophysiology of Post-COVID syndromes: a new perspective
  • T6 35264003 ↗Long-term outcomes of pediatric infections: from traditional infectious diseases to long Covid
  • T6 33785495 ↗Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-
  • T6 35472304 ↗Clinical characteristics with inflammation profiling of long COVID and association with 1-year recov
  • T6 34582441 ↗Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study
Low carbohydrate diet intervention
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT05836402 ↗Long COVID-19 Syndrome Lifestyle Intervention Study
  • T6 38123343 ↗Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Dise
Low-dose sirolimus
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT06960928 ↗Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19
  • T6 41096951 ↗Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lu
  • T6 39936727 ↗Brazilian Thoracic Association recommendations for the management of lymphangioleiomyomatosis
MSC-derived exosomes
T1
T1 — RCT in LC/PASC/PACVS
Harm signalLong COVID
16 sources
  • T1HARM NCT05808400 ↗Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Exosomes in Treating Chronic Cough After
  • T6INDIRECT 32454187 ↗Review of trials currently testing treatment and prevention of COVID-19
  • T6INDIRECT 35782071 ↗Association between Mesenchymal Stem Cells and COVID-19 Therapy: Systematic Review and Current Trend
  • T6 35927511 ↗The roles of extracellular vesicles in the immune system
  • T6 35787632 ↗Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next g
  • T6 38378653 ↗Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatme
  • T6 38152837 ↗Engineered Exosome for Drug Delivery: Recent Development and Clinical Applications
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6INDIRECT 35279630 ↗Mesenchymal stem cell treatment for COVID-19
  • T6INDIRECT 36015310 ↗Practical Considerations for Translating Mesenchymal Stromal Cell-Derived Extracellular Vesicles fro
  • T6INDIRECT 37763198 ↗Fresh Umbilical Cord Blood-A Source of Multipotent Stem Cells, Collection, Banking, Cryopreservation
  • T6INDIRECT 34685567 ↗Mesenchymal Stem Cells in the Treatment of COVID-19, a Promising Future
  • T6INDIRECT 38275749 ↗Mesenchymal Stem Cell-Based Therapies in the Post-Acute Neurological COVID Syndrome: Current Landsca
  • T6INDIRECT 38738585 ↗Extracellular vesicles as human therapeutics: A scoping review of the literature
  • T6INDIRECT 37874422 ↗ESICM LIVES 2023
  • T6 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
Maltodextrin
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
30 sources
  • T1 NCT06620406 ↗Synbiotic Therapy for NP-PASC
  • T6INDIRECT 38270314 ↗The effect of COVID-19 and COVID-19 vaccination on serum anti-Mullerian hormone: A systematic review
  • T6INDIRECT 37175942 ↗Endotheliopathy in Acute COVID-19 and Long COVID
  • T6INDIRECT 36409650 ↗A systematic review of the biological mediators of fat taste and smell
  • T6INDIRECT 36186977 ↗The rationale for the treatment of long-Covid symptoms - A cardiologist's view
  • T6INDIRECT 38424099 ↗Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised control
  • T6INDIRECT 35011103 ↗Effects of <i>Loigolactobacillus coryniformis</i> K8 CECT 5711 on the Immune Response of Elderly Sub
  • T6INDIRECT 39599737 ↗Effect of Postbiotic <i>Bifidobacterium longum</i> CECT 7347 on Gastrointestinal Symptoms, Serum Bio
  • T6INDIRECT 36084236 ↗Palmitoylethanolamide Reduces Proinflammatory Markers in Unvaccinated Adults Recently Diagnosed with
  • T6INDIRECT 39683507 ↗Efficacy of ETB-F01, Heat-Killed <i>Akkermansia muciniphila</i> Strain EB-AMDK19, in Patients with R
  • T6 32857878 ↗Thrombosis in COVID-19
  • T6 21821740 ↗Oxidoreductive cellulose depolymerization by the enzymes cellobiose dehydrogenase and glycoside hydr
  • T6 23102010 ↗Production of four Neurospora crassa lytic polysaccharide monooxygenases in Pichia pastoris monitore
  • T6INDIRECT 34937265 ↗Central retinal vein occlusion post-COVID-19 vaccination
  • T6INDIRECT 36828919 ↗Long-term interplay between COVID-19 and chronic kidney disease
  • T6INDIRECT 36686624 ↗Guillain-Barré syndrome associated with COVID-19: A systematic review
  • T6INDIRECT 36033885 ↗Microbiota and COVID-19: Long-term and complex influencing factors
  • T6INDIRECT 34889662 ↗Does COVID-19 Cause Hypertension?
  • T6INDIRECT 34755562 ↗Covid-19-Induced Dysautonomia: A Menace of Sympathetic Storm
  • T6INDIRECT 34115763 ↗Ayurveda botanicals in COVID-19 management: An in silico multi-target approach
  • T6 27877783 ↗A review on powder-based additive manufacturing for tissue engineering: selective laser sintering an
  • T6 11729261 ↗Comparative biology of IncQ and IncQ-like plasmids
  • T6 33646622 ↗Sex-based differences in severity and mortality in COVID-19
  • T6 36386929 ↗Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, agei
  • T6 34896650 ↗Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Repor
  • T6 22123987 ↗Synthesis of three advanced biofuels from ionic liquid-pretreated switchgrass using engineered Esche
  • T6 10899854 ↗Attenuated nontoxinogenic and nonencapsulated recombinant Bacillus anthracis spore vaccines protect
  • T6 24324265 ↗A C4-oxidizing lytic polysaccharide monooxygenase cleaving both cellulose and cello-oligosaccharides
  • T6 25201969 ↗A family of starch-active polysaccharide monooxygenases
  • T6 22132148 ↗The putative endoglucanase PcGH61D from Phanerochaete chrysosporium is a metal-dependent oxidative e
Microdosing of mindfulness
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05676008 ↗A Study of Positive Emotions With Long COVID-19
Microsponge
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT05970731 ↗Directed Topical Drug Delivery for Treatment for PASC Hyposmia
  • T6 34825334 ↗Biocosmetics: technological advances and future outlook
Mid and long-term neurological and neuropsychiatric manifestations of post-COVID
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
6 sources
  • T1 35121209 ↗Mid and long-term neurological and neuropsychiatric manifestations of post-COVID-19 syndrome: A meta
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 37867774 ↗Susceptibility and severity of COVID-19 and risk of psychiatric disorders in European populations: a
  • T6INDIRECT 38656063 ↗Long COVID-19 and mnemonic effects: an integrative literature review
Mind Body Intervention #1
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06045338 ↗Mind Body Intervention for Long COVID-19
Mindfulness - Mindful Awareness Practices
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05566379 ↗Mindfulness in Post Acute Sequelae of SARS-CoV-2 Infection (PASC) Dysautonomia
Minimal-Dose Home-Based Resistance Exercise
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
Modafinil
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDPOTS
57 sources
  • T1 NCT06404086 ↗RECOVER-SLEEP: Platform Protocol
  • T1 NCT06404099 ↗RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)
  • T2REGISTERED-ONLY NCT00262470 ↗Treatment of Orthostatic Intolerance
  • T2REGISTERED-ONLY NCT01988883 ↗Modafinil and Cognitive Function in POTS
  • T6INDIRECT 39882369 ↗Oral medications for the treatment of postural orthostatic tachycardia syndrome; a systematic review
  • T6INDIRECT 38228914 ↗Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for
  • T6INDIRECT 39207396 ↗Undervaluing nondrug rewards or overvaluing cocaine? Cocaine demand relates to cocaine use severity
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 34390682 ↗Post-COVID-19 Tachycardia Syndrome: A Distinct Phenotype of Post-Acute COVID-19 Syndrome
  • T6INDIRECT 33723532 ↗Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrom
  • T6 33755344 ↗Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 "long haulers"
  • T6 34346558 ↗Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fati
  • T6 35577469 ↗Telehealth cancer-related fatigue clinic model for cancer survivors: a pilot randomised controlled t
  • T6 38384879 ↗Self-managing symptoms of Long COVID: an education and strategies research protocol
  • T6HARM 35277411 ↗Pharmacological and non-pharmacological interventions for adults with ADHD: protocol for a systemati
  • T6INDIRECT 27153153 ↗Pharmacological treatment for Kleine-Levin syndrome
  • T6INDIRECT 35651342 ↗Sleep Disturbances in Pediatric Craniopharyngioma: A Systematic Review
  • T6INDIRECT 40653179 ↗The evidence for treatments for postural orthostatic tachycardia syndrome: a systematic review of ra
  • T6INDIRECT 41225175 ↗Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS)
  • T2 25222185 ↗Hemodynamic profiles and tolerability of modafinil in the treatment of postural tachycardia syndrome
  • T6INDIRECT 37447210 ↗Combination of Chemically Characterized Pomegranate Extract and Hydrophilic Vitamins against Prolong
  • T6 22519513 ↗The solute carrier 6 family of transporters
  • T6INDIRECT 23753844 ↗Postural tachycardia syndrome (POTS)
  • T6 25980576 ↗2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tach
  • T6 34144933 ↗Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019
  • T6INDIRECT 29744873 ↗Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - as
  • T6INDIRECT 26447539 ↗Interventions for fatigue in Parkinson's disease
  • T6INDIRECT 36190739 ↗Pharmacological interventions for prevention of weight gain in people with schizophrenia
  • T6INDIRECT 27863901 ↗A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease f
  • T6INDIRECT 32402075 ↗Pharmacological Augmentation in Unipolar Depression: A Guide to the Guidelines
  • T6INDIRECT 36138129 ↗The impact of pharmacological and non-pharmacological interventions on physical health outcomes in p
  • T6INDIRECT 36971690 ↗Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)
  • T6INDIRECT 20679638 ↗Atomoxetine for depression and other neuropsychiatric symptoms in Parkinson disease
  • T6INDIRECT 17134849 ↗Safety, tolerability and efficacy of levodopa-carbidopa treatment for cocaine dependence: two double
  • T6 30653247 ↗Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review
  • T6INDIRECT 35853576 ↗Postural orthostatic tachycardia syndrome as a sequela of COVID-19
  • T6INDIRECT 33421734 ↗The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacol
  • T6INDIRECT 36946625 ↗An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing m
  • T6INDIRECT 36002784 ↗Treatment of Cushing's syndrome with osilodrostat: practical applications of recent studies with cas
  • T6INDIRECT 33681293 ↗Neurological Consequences of SARS-CoV-2 Infection and Concurrence of Treatment-Induced Neuropsychiat
  • T6INDIRECT 36169154 ↗Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of aut
  • T6 39125722 ↗Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detectio
  • T6 34646278 ↗Multiple Sclerosis and SARS-CoV-2: Has the Interplay Started?
  • T6 35454890 ↗A New Approach to Understanding Cancer-Related Fatigue: Leveraging the 3P Model to Facilitate Risk P
  • T6 35883527 ↗Pathological Features and Neuroinflammatory Mechanisms of SARS-CoV-2 in the Brain and Potential Ther
  • T6INDIRECT 22021174 ↗The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor sy
  • T6INDIRECT 26084539 ↗International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors
  • T6INDIRECT 19484833 ↗Evidence-based recommendations for the assessment and management of sleep disorders in older persons
  • T6INDIRECT 25200111 ↗Drooling in Parkinson's disease: a review
  • T6INDIRECT 29101940 ↗REM Sleep Behavior Disorder: Diagnosis, Clinical Implications, and Future Directions
  • T6 26595642 ↗Lewy body dementias
  • T6 28837986 ↗Sleep Disturbance, Cognitive Decline, and Dementia: A Review
  • T6 24699931 ↗Non-motor Parkinson's: integral to motor Parkinson's, yet often neglected
  • T6 33924103 ↗Treatment Options for Motor and Non-Motor Symptoms of Parkinson's Disease
  • T6 19603170 ↗Primary biliary cirrhosis
  • T6 23065655 ↗A practical guide to the therapy of narcolepsy and hypersomnia syndromes
  • T6 20815187 ↗Fatigue in multiple sclerosis: mechanisms, evaluation, and treatment
Multicomponent intervention
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
23 sources
  • T1 NCT06492590 ↗Long COVID-19 Intervention (COVIDL/MIQoL)
  • T6INDIRECT 36098262 ↗Long COVID in children and adolescents
  • T6INDIRECT 38695826 ↗Measures implemented in the school setting to contain the COVID-19 pandemic
  • T6INDIRECT 35037252 ↗Measures implemented in the school setting to contain the COVID-19 pandemic
  • T6INDIRECT 37784017 ↗Learning from the covid-19 outbreaks in long-term care facilities: a systematic review
  • T6INDIRECT 35533528 ↗Effects of mental health interventions among people hospitalized with COVID-19 infection: A systemat
  • T6INDIRECT 35442432 ↗Effect of Culturally Tailored, Internet-Delivered Cognitive Behavioral Therapy for Insomnia in Black
  • T6INDIRECT 39813042 ↗Palliative Care Initiated in the Emergency Department: A Cluster Randomized Clinical Trial
  • T6INDIRECT 38941601 ↗The Effect of an mHealth Self-Monitoring Intervention (MI-BP) on Blood Pressure Among Black Individu
  • T6 35402784 ↗Post-acute sequelae of COVID-19 (PASC): a meta-narrative review of pathophysiology, prevalence, and
  • T6 35143770 ↗Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in Eng
  • T6 37712135 ↗Lifestyle management of hypertension: International Society of Hypertension position paper endorsed
  • T6HARM 33949747 ↗Suicidal ideation and thoughts of self-harm during the COVID-19 pandemic: The role of COVID-19-relat
  • T6INDIRECT 33936607 ↗COVID-19, when fourteen days are not enough-A case series of affected healthcare workers
  • T6INDIRECT 34297318 ↗Abstracts from the 2021 Annual Meeting of the Society of General Internal Medicine
  • T6INDIRECT 34633565 ↗ESICM LIVES 2021: Part 1
  • T6INDIRECT 39033994 ↗Rationale, Design and Baseline Characteristics of a Randomized Controlled Trial of a Cardiovascular
  • T6 39458423 ↗Acute Sarcopenia: Mechanisms and Management
  • T6 39294611 ↗Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during
  • T6 37110200 ↗Amino Acid Profiles in Older Adults with Frailty: Secondary Analysis from MetaboFrail and BIOSPHERE
  • T6 38126653 ↗Scientists of Tomorrow/ Cientistas do Amanhã : a project to inspire, stimulate scientific thinking,
  • T6 34932190 ↗Abstracts of the 17th Congress of the European Geriatric Medicine Society : Live from Athens and Onl
  • T6 33166163 ↗Behavioral economics of substance use: Understanding and reducing harmful use during the COVID-19 pa
Multimodal intervention in Long Covid19
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
Muse S™ Headband system
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
N-803
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
23 sources
  • T1REGISTERED-ONLY NCT07108036 ↗A Study to Assess Anktiva in Patients With Long Covid-19.
  • T6INDIRECT 34167876 ↗Prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: A syst
  • T6INDIRECT 36889797 ↗Comparison of mental health symptoms before and during the covid-19 pandemic: evidence from a system
  • T6INDIRECT 33766163 ↗Prevalence of depressive symptoms among Chinese university students amid the COVID-19 pandemic: a sy
  • T6INDIRECT 35785594 ↗Persistent neurological manifestations in long COVID-19 syndrome: A systematic review and meta-analy
  • T6INDIRECT 36098262 ↗Long COVID in children and adolescents
  • T6INDIRECT 33380413 ↗Effectiveness, safety and acceptability of medical abortion at home versus in the clinic: a systemat
  • T6INDIRECT 35866452 ↗Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 33151274 ↗The impact of the COVID-19 pandemic on the care and management of patients with acute cardiovascular
  • T6INDIRECT 35544369 ↗Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age
  • T6INDIRECT 34559863 ↗Social distancing in America: Understanding long-term adherence to COVID-19 mitigation recommendatio
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 38378653 ↗Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatme
  • T6INDIRECT 35027697 ↗Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the Internat
  • T6INDIRECT 33836148 ↗6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective coho
  • T6INDIRECT 35143770 ↗Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in Eng
  • T6 24661096 ↗Protein design: toward functional metalloenzymes
  • T6 36454715 ↗CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond
  • T6 3070321 ↗Linkage map of Salmonella typhimurium, edition VII
  • T6 33785495 ↗Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-
  • T6 35472304 ↗Clinical characteristics with inflammation profiling of long COVID and association with 1-year recov
NE3107
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT06847191 ↗NE3107 in Adults With Neurological Symptoms of Long COVID
  • T6 39174535 ↗Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strateg
  • T6 41767744 ↗Inflammatory mechanisms underlying early Alzheimer's disease pathology: evidence from the aging rhes
NeuroFlex
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT05705193 ↗Brain-Training Treatment for Long COVID in Older Adults
  • T6 38755688 ↗RECOVER-NEURO: study protocol for a multi-center, multi-arm, phase 2, randomized, active comparator
  • T6 PMC11925478 ↗ABSTRACTS
Nivolumab and Ipilimumab
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
14 sources
  • T1REGISTERED-ONLY NCT05597800 ↗Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and
  • T6INDIRECT 41029573 ↗The efficacy analysis of neoadjuvant chemoimmunotherapy followed by surgery in stage III locally adv
  • T6 29564184 ↗How does the tumor microenvironment play a role in hepatobiliary tumors?
  • T6 32650215 ↗Recommendations for detection, prioritization, and treatment of thoracic oncology patients during th
  • T6 37391394 ↗SARS-CoV-2 infection and COVID-19 vaccination in cancer patients undergoing immune checkpoint inhibi
  • T6 40211538 ↗DNA-based immunotherapy for cancer: In vivo approaches for recalcitrant targets
  • T6 35830116 ↗Brazilian Society of Cardiology Guideline on Myocarditis - 2022
  • T6INDIRECT 36561623 ↗Diabetes insipidus: A rare endocrine complication of immune check point inhibitors: A case report an
  • T6INDIRECT 38929875 ↗The Long Journey towards Personalized Targeted Therapy in Poorly Differentiated Thyroid Carcinoma (P
  • T6INDIRECT 36143403 ↗Immune Checkpoint Inhibitor-Induced Myocarditis vs. COVID-19 Vaccine-Induced Myocarditis-Same or Dif
  • T6INDIRECT 40542608 ↗Special Issue: Abstracts of the 11&lt;sup&gt;th&lt;/sup&gt; Congress of the European Academy of Neur
  • T6INDIRECT 36648635 ↗World Molecular Imaging Congress 2022
  • T4 PMC9548092 ↗UEG Week 2022 Oral Presentations
  • T6 40733649 ↗Research and Clinical Progress of Therapeutic Tumor Vaccines
No Interventions
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
22 sources
  • T1REGISTERED-ONLY NCT07352254 ↗OutreAch MediCal Care for HousEbound Patients With Post-COVID-19 Syndrome or ME/CFS of Any Cause (AC
  • T6INDIRECT 34373540 ↗More than 50 long-term effects of COVID-19: a systematic review and meta-analysis
  • T6INDIRECT 36951832 ↗Risk Factors Associated With Post-COVID-19 Condition: A Systematic Review and Meta-analysis
  • T6INDIRECT 33760236 ↗Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 33661992 ↗Population risk factors for severe disease and mortality in COVID-19: A global systematic review and
  • T6INDIRECT 35124265 ↗Prevalence of post-acute COVID-19 syndrome symptoms at different follow-up periods: a systematic rev
  • T6INDIRECT 34634250 ↗Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T6INDIRECT 36681084 ↗Protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron va
  • T6INDIRECT 32503818 ↗Medical and Surgical Education Challenges and Innovations in the COVID-19 Era: A Systematic Review
  • T6INDIRECT 33180097 ↗Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Random
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34281357 ↗Myocarditis With COVID-19 mRNA Vaccines
  • T6 33497610 ↗Adaptive immunity to SARS-CoV-2 and COVID-19
  • T6 38433280 ↗NF-κB in biology and targeted therapy: new insights and translational implications
  • T6 22896693 ↗The pancreas cancer microenvironment
  • T6 32422178 ↗Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy
  • T6 35304603 ↗Exerkines in health, resilience and disease
Non-invasive vagus nerve stimulation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
22 sources
  • T1 NCT05630040 ↗VNS for Long-COVID-19
  • T6INDIRECT 39456932 ↗Rheumatoid Arthritis and COVID-19 at the Intersection of Immunology and Infectious Diseases: A Relat
  • T6INDIRECT 36940750 ↗Prefrontal tDCS modulates autonomic responses in COVID-19 inpatients
  • T6INDIRECT 41927730 ↗Post-exercise auricular vagus nerve stimulation modulates autonomic and recovery responses in physic
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6 33324324 ↗Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19
  • T6 35054856 ↗Disorders of the Cholinergic System in COVID-19 Era-A Review of the Latest Research
  • T6 36002874 ↗A pilot randomized controlled trial of supervised, at-home, self-administered transcutaneous auricul
  • T6 35463130 ↗Non-invasive Vagus Nerve Stimulation for COVID-19: Results From a Randomized Controlled Trial (SAVIO
  • T6 40481908 ↗Transcutaneous Auricular Vagal Nerve Stimulation for the Treatment of the Fatigue Syndrome in Patien
  • T6 42342403 ↗Effects of auricular vagal neuromodulation therapy combined with slow-paced diaphragmatic breathing
  • T4 PMC13290870 ↗Without getting under your skin: non-invasive stimulation activates the vagus nerve
  • T4 PMC12941859 ↗Postural Orthostatic Tachycardia Syndrome, Menopause and Hormone Replacement Therapy: Clinical Decis
  • T6INDIRECT 40545525 ↗Abstracts from the 18 th European Headache Congress (EHC) : Rotterdam, The Netherlands. 4-7 December
  • T6INDIRECT 40553043 ↗Classification of Individuals With COVID-19 and Post-COVID-19 Condition and Healthy Controls Using H
  • T6INDIRECT 38426548 ↗Association of Chiropractic Colleges Educational Conference and Research Agenda Conference 2024: The
  • T6 41373850 ↗Integrative Neuroimmune Role of the Parasympathetic Nervous System, Vagus Nerve and Gut Microbiota i
  • T6 41299695 ↗The virology of Omicron: pathophysiology, immune regulation, and clinical impact of SARS-CoV-2 sub v
  • T6 36004877 ↗Understanding the Pivotal Role of the Vagus Nerve in Health from Pandemics
  • T6 40254579 ↗Long COVID clinical evaluation, research and impact on society: a global expert consensus
  • T6 38756213 ↗Transcutaneous vagus nerve stimulation improves Long COVID symptoms in a female cohort: a pilot stud
  • T6 40261198 ↗Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID
Olfactory Training Kit - "The Olfactory Kit, by AdvancedRx"
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06204432 ↗Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction
On Site Exercise Rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
WithdrawnLong COVID
1 source
  • T1WITHDRAWN NCT05398692 ↗Long COVID-19 Rehabilitation & Recovery Research Program
Osteopathic Manipulative Therapy Long-COVID protocol
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06883513 ↗Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID
Osteopathic Manipulative Therapy NOT Long-COVID treatment protocol
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06883513 ↗Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID
PASC CoRE
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
8 sources
  • T1 NCT05965739 ↗RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS I
  • T1 NCT05965752 ↗RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Lo
  • T6INDIRECT 41212544 ↗Evaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial
  • T6 37745021 ↗Characterization of long COVID temporal sub-phenotypes by distributed representation learning from e
  • T6 38755688 ↗RECOVER-NEURO: study protocol for a multi-center, multi-arm, phase 2, randomized, active comparator
  • T6 38865966 ↗Challenges and opportunities in long COVID research
  • T6 PPR674291 ↗Characterization of Long Covid Temporal Sub-Phenotypes by Distributed Learning from Electronic Healt
  • T6INDIRECT 38188200 ↗Spinal cord infarction attributed to SARS-CoV-2, with post-acute sequelae of COVID-19: A case report
Paragon Novel Metabolic Regulator
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT07627815 ↗Evaluating the Safety and Efficacy of PNMR as Treatment for Long COVID
Pascal device
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06739668 ↗Humanity Neurotech Device Clinical Trial in Adults With Long COVID Cognitive Dysfunction
Peer Mentoring
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
25 sources
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
  • T6INDIRECT 41101955 ↗Interventions to enhance gender equity in academic medicine: a systematic review
  • T6INDIRECT 39036099 ↗Medical education during the coronavirus disease 2019 pandemic: an umbrella review
  • T6INDIRECT 40597208 ↗Global perspectives on challenges, coping strategies, and future preparedness of nursing home staff
  • T6INDIRECT 35073499 ↗Pilot Social Network Weight Loss Intervention With Two Immigrant Populations During the COVID-19 Pan
  • T6 34887173 ↗Mind the gap: Inequalities in mental health care and lack of social support in Parkinson disease
  • T6 40746683 ↗A review of recruitment and retention strategies in U.S. local health departments: insights and prac
  • T6 36082018 ↗Using Peer Power to Reduce Health Disparities: Implementation of a Diabetes Support Coach Program in
  • T6 35070487 ↗The NCSBN 2022 Environmental Scan: Resiliency, Achievement, and Public Protection
  • T6 37753982 ↗Teacher Support, Academic Self-Efficacy, Student Engagement, and Academic Achievement in Emergency O
  • T6 33148602 ↗Rapid implementation and improvement of a virtual student placement model in response to the COVID-1
  • T6INDIRECT 34297318 ↗Abstracts from the 2021 Annual Meeting of the Society of General Internal Medicine
  • T6INDIRECT 37790179 ↗Proceedings of the Sixth Conference of the Society for Implementation Research Collaboration (SIRC)
  • T6INDIRECT 34011360 ↗Proceedings from the 13th Annual Conference on the Science of Dissemination and Implementation : Vir
  • T6INDIRECT 38504346 ↗Proceedings of the 6th UK and Ireland implementation science research conference
  • T6INDIRECT 37465735 ↗International Congress on Academic Medicine: 2023 medical education abstracts: United today for a he
  • T6INDIRECT 34235134 ↗Extending the Population Health Workforce Through Service Learning Internships During COVID: A Commu
  • T6 39811040 ↗Dissecting Loneliness in the Digital Age: An Insight into the Experiences of Medical Students Amid a
  • T6 37915328 ↗Pedagogical impact of integration of musculoskeletal anatomy blended learning on physiotherapy educa
  • T6 34926835 ↗Program Abstracts from The GSA 2021 Annual Scientific Meeting, "Disruption to Transformation: Aging
  • T6 34544746 ↗Research and Education Poster Abstracts Presented at the 122nd Virtual Annual Meeting of the America
  • T6 31898181 ↗The Veterans Health Administration's Contribution to Cancer Education
  • T6 36448246 ↗Training and cultivating the translational science workforce: Responses of Clinical and Translationa
  • T6 38664744 ↗Risk factors for smoking in adolescence: evidence from a cross-sectional survey in Switzerland
  • T6 38181035 ↗The impact of online education during the Covid-19 pandemic on the professional identity formation o
Pentoxifylline
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
20 sources
  • T1 NCT05513560 ↗RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine
  • T1 39446164 ↗Pentoxifylline in COVID-19 and considerations for its research in long COVID
  • T6INDIRECT 38695785 ↗Effects of additional exercise therapy after a successful vascular intervention for people with symp
  • T6INDIRECT 34291812 ↗Interventions for the prevention of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 36062970 ↗Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 34291813 ↗Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 36063364 ↗Interventions for the prevention of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 35948654 ↗Epidemiology and clinical evolution of non-multisystem inflammatory syndrome (MIS-C) dermatological
  • T6INDIRECT 42210924 ↗Neurobiological mechanisms of olfactory dysfunction: a ten-year bibliometric and visualization analy
  • T6INDIRECT 37944311 ↗Alpha-lipoic acid does not improve olfactory training results in olfactory loss due to COVID-19: a d
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 36899952 ↗Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome and Potential Therapeutic
  • T6 35373533 ↗International consensus statement on allergy and rhinology: Olfaction
  • T6INDIRECT 36713204 ↗The role of oxidative stress in the pathogenesis of infections with coronaviruses
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 33668969 ↗Drug Repurposing in the COVID-19 Era: Insights from Case Studies Showing Pharmaceutical Peculiaritie
  • T6INDIRECT 38998660 ↗<i>Aloe vera</i>-An Extensive Review Focused on Recent Studies
  • T6 33240091 ↗Challenges for Drug Repurposing in the COVID-19 Pandemic Era
  • T6 37511055 ↗Endothelin-1 in Health and Disease
  • T6 37649125 ↗Neurological manifestations of SARS-CoV-2: complexity, mechanism and associated disorders
Personalized Cardiopulmonary Rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
2 sources
  • T1REGISTERED-ONLY NCT06404060 ↗RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
  • T1 NCT06404047 ↗RECOVER-ENERGIZE Platform Protocol
Personalized multidisciplinary day-hospital intervention
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05532904 ↗Multidisciplinary Day-hospital Versus Waiting List Management of Post-COVID-19 Persistent Symptoms (
Physical Fatigue
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
32 sources
  • T1REGISTERED-ONLY NCT07278388 ↗Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2
  • T6INDIRECT 34752489 ↗A mixed-methods systematic review of post-viral fatigue interventions: Are there lessons for long Co
  • T6INDIRECT 35341944 ↗Aromatherapy blend of thyme, orange, clove bud, and frankincense boosts energy levels in post-COVID-
  • T6INDIRECT 36693536 ↗Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC)
  • T6INDIRECT 36674117 ↗Positive Impacts of a Four-Week Neuro-Meditation Program on Cognitive Function in Post-Acute Sequela
  • T6INDIRECT 36700245 ↗Randomized controlled trial of home-based vs. hospital-based pulmonary rehabilitation in post COVID-
  • T6INDIRECT 38528512 ↗Effect of home-based pulmonary rehabilitation on exercise capacity in post COVID-19 patients: a rand
  • T6INDIRECT 38272997 ↗Transcranial direct current stimulation (tDCS) in the treatment of neuropsychiatric symptoms of long
  • T1 37698618 ↗Physical exercise as a treatment for persisting symptoms post-COVID infection: review of ongoing stu
  • T6INDIRECT 36042189 ↗A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pand
  • T6 33166287 ↗Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial i
  • T6 34163090 ↗Long COVID in a prospective cohort of home-isolated patients
  • T6 36051247 ↗Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID sympt
  • T6INDIRECT 35287333 ↗Long-Term COVID 19 Sequelae in Adolescents: the Overlap with Orthostatic Intolerance and ME/CFS
  • T6INDIRECT 35636906 ↗Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
  • T4 34051516 ↗Physical and mental health complications post-COVID-19: Scoping review
  • T6INDIRECT 34649946 ↗Neuropsychologic Profiles and Cerebral Glucose Metabolism in Neurocognitive Long COVID Syndrome
  • T6INDIRECT 36873426 ↗Structural brain changes in patients with post-COVID fatigue: a prospective observational study
  • T6INDIRECT 34564089 ↗A Randomized Controlled Trial of the Efficacy of Systemic Enzymes and Probiotics in the Resolution o
  • T6 37457901 ↗Post-COVID cognitive dysfunction: current status and research recommendations for high risk populati
  • T6 35454890 ↗A New Approach to Understanding Cancer-Related Fatigue: Leveraging the 3P Model to Facilitate Risk P
  • T6 36202253 ↗Post-viral fatigue in COVID-19: A review of symptom assessment methods, mental, cognitive, and physi
  • T6 35414261 ↗Brain Fog in Hypothyroidism: What Is It, How Is It Measured, and What Can Be Done About It
  • T6 33381041 ↗Panacis Quinquefolii Radix: A Review of the Botany, Phytochemistry, Quality Control, Pharmacology, T
  • T6 37064029 ↗A review of cytokine-based pathophysiology of Long COVID symptoms
  • T6 34494964 ↗Severe Fatigue in Long COVID: Web-Based Quantitative Follow-up Study in Members of Online Long COVID
  • T6 35085824 ↗Neuropsychological, Medical, and Psychiatric Findings After Recovery From Acute COVID-19: A Cross-se
  • T6 32758891 ↗Into the looking glass: Post-viral syndrome post COVID-19
  • T6 35734582 ↗Non-invasive brain stimulation and neuroenhancement
  • T6 33359928 ↗Neuropsychological and neurophysiological correlates of fatigue in post-acute patients with neurolog
  • T6 34069603 ↗European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE): Expert Consensus
  • T6 34563706 ↗Mast cell activation symptoms are prevalent in Long-COVID
Physical activity behavioural modification
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT05752331 ↗Feasibility of Personalised Health Behaviour Coaching to Support Symptoms and Activities of Daily Li
  • T6 35615417 ↗ERS International Congress 2021: highlights from the Respiratory Clinical Care and Physiology Assemb
Physical therapy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
27 sources
  • T1REGISTERED-ONLY NCT07254377 ↗Design and Validation of Innovative Strategies Based on Dual-Task Approach
  • T6INDIRECT 34373540 ↗More than 50 long-term effects of COVID-19: a systematic review and meta-analysis
  • T6INDIRECT 34167876 ↗Prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: A syst
  • T6INDIRECT 33262076 ↗Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis
  • T6INDIRECT 38101521 ↗Persistence of post-COVID symptoms in the general population two years after SARS-CoV-2 infection: A
  • T6INDIRECT 33729021 ↗Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus di
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T1 37725376 ↗Rehabilitation Interventions for Physical Capacity and Quality of Life in Adults With Post-COVID-19
  • T6INDIRECT 36560633 ↗Long-COVID Symptoms in Individuals Infected with Different SARS-CoV-2 Variants of Concern: A Systema
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 34741822 ↗Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who rec
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 34248921 ↗Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Con
  • T6INDIRECT 34997689 ↗Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19
  • T6INDIRECT 36555931 ↗Age, Sex and Previous Comorbidities as Risk Factors Not Associated with SARS-CoV-2 Infection for Lon
  • T6INDIRECT 32475821 ↗The Stanford Hall consensus statement for post-COVID-19 rehabilitation
  • T6INDIRECT 36051247 ↗Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID sympt
  • T6INDIRECT 35307156 ↗2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocard
  • T6 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6 32885037 ↗COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside
  • T6 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6 34216297 ↗COVID-19 and Myositis: What We Know So Far
  • T6 37277738 ↗The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap
  • T6 33347610 ↗Silent hypoxaemia in COVID-19 patients
  • T6 35079817 ↗Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
  • T6 33807869 ↗Defining Post-COVID Symptoms (Post-Acute COVID, Long COVID, Persistent Post-COVID): An Integrative C
Prednisolone /
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
23 sources
  • T1 NCT05638633 ↗Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome
  • T6INDIRECT 33246166 ↗COVID-19 in solid organ transplant recipients: A systematic review and meta-analysis of current lite
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T6INDIRECT 36921716 ↗COVID-19-associated mucormycosis: a systematic review and meta-analysis of 958 cases
  • T6INDIRECT 34396514 ↗Systemic corticosteroids for the treatment of COVID-19
  • T6INDIRECT 34839149 ↗A systematic review of cases of CNS demyelination following COVID-19 vaccination
  • T6INDIRECT 36988252 ↗Adverse events following COVID-19 mRNA vaccines: A systematic review of cardiovascular complication,
  • T6INDIRECT 34386902 ↗Association of CNS demyelination and COVID-19 infection: an updated systematic review
  • T6INDIRECT 33036570 ↗Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
  • T6INDIRECT 33429174 ↗Corticosteroid nasal spray for recovery of smell sensation in COVID-19 patients: A randomized contro
  • T6INDIRECT 33084029 ↗Seroprevalence of anti-SARS-CoV-2 antibodies in COVID-19 patients and healthy volunteers up to 6 mon
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34156034 ↗Epidemiology, clinical profile, management, and outcome of COVID-19-associated rhino-orbital-cerebra
  • T6INDIRECT 32201335 ↗Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 38378653 ↗Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatme
  • T6INDIRECT 33219837 ↗Severe COVID-19, multisystem inflammatory syndrome in children, and Kawasaki disease: immunological
  • T6INDIRECT 32637987 ↗The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 34716418 ↗Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison
  • T6 33166287 ↗Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial i
Processing Speed Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
7 sources
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
  • T2REGISTERED-ONLY NCT07523113 ↗ME/CFS Brain Fog: Cognitive Rehabilitation Trial
  • T6 PMC11688754 ↗Full GSA 2024 Abstract Book PDF
  • T6 24960594 ↗NIH Toolbox Cognitive Battery (NIHTB-CB): the NIHTB Pattern Comparison Processing Speed Test
  • T6 25859431 ↗Psychological intervention for improving cognitive function in cancer survivors: a literature review
  • T6 36175973 ↗Effectiveness of the Unified Barlow Protocol (UP) and neuropsychological treatment in cancer survivo
  • T6 PMC6840740 ↗Program Abstracts from the GSA 2019 Annual Scientific Meeting “Strength in Age—Harnessing the Power
Psychotherapy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredWithdrawnLong COVIDME/CFS
56 sources
  • T1REGISTERED-ONLY NCT06042751 ↗Psychosomatic, Physical Activity or Both for Post-covid19 Syndrom
  • T2WITHDRAWN NCT05967052 ↗Investigation of Treating Chronic Fatigue Syndrome After COVID With Pharmacotherapy (Pregabalin) or
  • T6INDIRECT 36731907 ↗Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regres
  • T6INDIRECT 33781283 ↗Mental burden and its risk and protective factors during the early phase of the SARS-CoV-2 pandemic:
  • T6INDIRECT 33426733 ↗Cerebral venous thrombosis and severe acute respiratory syndrome coronavirus-2 infection: A systemat
  • T6INDIRECT 34592585 ↗Telehealth utilization during the Covid-19 pandemic: A systematic review
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 34600257 ↗The early impact of COVID-19 on the incidence, prevalence, and severity of alcohol use and other dru
  • T6INDIRECT 36032234 ↗Post-COVID-19 fatigue: A systematic review
  • T6INDIRECT 34844624 ↗The impact of the novel coronavirus disease (COVID-19) pandemic on drug overdose-related deaths in t
  • T6INDIRECT 35322449 ↗A mixed-studies systematic review of the experiences of body image, disordered eating, and eating di
  • T6INDIRECT 36129719 ↗Effectiveness of Standard Sequential Bilateral Repetitive Transcranial Magnetic Stimulation vs Bilat
  • T6 32682460 ↗How mental health care should change as a consequence of the COVID-19 pandemic
  • T6 36192553 ↗How COVID-19 shaped mental health: from infection to pandemic effects
  • T6INDIRECT 20350028 ↗The effect of mindfulness-based therapy on anxiety and depression: A meta-analytic review
  • T6INDIRECT 22895961 ↗Exercise interventions on health-related quality of life for cancer survivors
  • T6INDIRECT 26730878 ↗Exercise-based cardiac rehabilitation for coronary heart disease
  • T6INDIRECT 22895974 ↗Exercise interventions on health-related quality of life for people with cancer during active treatm
  • T6INDIRECT 24805797 ↗Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis
  • T6INDIRECT 18165893 ↗Internet-administered cognitive behavior therapy for health problems: a systematic review
  • T6INDIRECT 24881045 ↗Bias due to lack of patient blinding in clinical trials. A systematic review of trials randomizing p
  • T6INDIRECT 11265953 ↗Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial
  • T6INDIRECT 28943228 ↗Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiet
  • T6INDIRECT 8555852 ↗Cognitive behaviour therapy for the chronic fatigue syndrome: a randomized controlled trial
  • T6 18923511 ↗The molecular neurobiology of depression
  • T6 23798298 ↗Lack of exercise is a major cause of chronic diseases
  • T6INDIRECT 32685700 ↗Germany's digital health reforms in the COVID-19 era: lessons and opportunities for other countries
  • T6INDIRECT 35373533 ↗International consensus statement on allergy and rhinology: Olfaction
  • T6INDIRECT 34682909 ↗Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): An Overview
  • T6INDIRECT 34027514 ↗Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort st
  • T6INDIRECT 34051516 ↗Physical and mental health complications post-COVID-19: Scoping review
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 33441072 ↗PTSD in the COVID-19 Era
  • T6 34155207 ↗SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
  • T6 37713568 ↗Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epide
  • T6 36202135 ↗Clinical guidelines for the use of lifestyle-based mental health care in major depressive disorder:
  • T6 33049215 ↗COVID-19 and Cancer: Current Challenges and Perspectives
  • T6 34505369 ↗The growing field of digital psychiatry: current evidence and the future of apps, social media, chat
  • T6 33444560 ↗Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in t
  • T6 41092926 ↗Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life e
  • T6INDIRECT 23076904 ↗Printed educational materials: effects on professional practice and healthcare outcomes
  • T6INDIRECT 30284240 ↗Psychological interventions for needle-related procedural pain and distress in children and adolesce
  • T6INDIRECT 24366490 ↗Cultural concepts of distress and psychiatric disorders: literature review and research recommendati
  • T6INDIRECT 20471738 ↗Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms
  • T6INDIRECT 15774430 ↗Depression in multiple sclerosis: a review
  • T6INDIRECT 12830308 ↗Patients presenting with somatic complaints: epidemiology, psychiatric comorbidity and management
  • T6INDIRECT 24518354 ↗Social media: a review and tutorial of applications in medicine and health care
  • T6INDIRECT 25365763 ↗Interoceptive dysfunction: toward an integrated framework for understanding somatic and affective di
  • T6 17716101 ↗Stress and health: psychological, behavioral, and biological determinants
  • T6 29884281 ↗Interoception and Mental Health: A Roadmap
  • T6 36116464 ↗Amyotrophic lateral sclerosis
  • T6 29876878 ↗Role of the Prefrontal Cortex in Pain Processing
  • T6 31379879 ↗The Role of Inflammation in Depression and Fatigue
  • T6 23459093 ↗The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses
  • T6 27159638 ↗Irritable bowel syndrome
  • T6 17488783 ↗Guidelines on the irritable bowel syndrome: mechanisms and practical management
Pulsed ectromagnetid field therapy
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05379517 ↗Pulmonary Rehabilitation Program With Pulsed Electromagnetic Field Therapy in Patients With Post-cov
Qigong
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
29 sources
  • T1 NCT05675995 ↗Qigong for Post Acute Sequelae of COVID-19 Infection
  • T6INDIRECT 37802177 ↗Effectiveness of Rehabilitation Interventions on Adults With COVID-19 and Post-COVID-19 Condition. A
  • T6INDIRECT 36833525 ↗Tai Chi Exercise for Mental and Physical Well-Being in Patients with Depressive Symptoms: A Systemat
  • T6INDIRECT 36249181 ↗Do patients with and survivors of COVID-19 benefit from telerehabilitation? A meta-analysis of rando
  • T6INDIRECT 36804363 ↗Health maintenance through home-based interventions for community-dwelling older people with sarcope
  • T6INDIRECT 35108624 ↗Respiratory rehabilitation in patients recovering from severe acute respiratory syndrome: A systemat
  • T6INDIRECT 40083165 ↗Effect of pulmonary rehabilitation for patients with long COVID-19: a systematic review and meta-ana
  • T6INDIRECT 38214047 ↗Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation
  • T6INDIRECT 35615091 ↗Use of Traditional, Complementary and Integrative Medicine During the COVID-19 Pandemic: A Systemati
  • T6INDIRECT 36982095 ↗Does Physical Exercise Enhance the Immune Response after Vaccination? A Systematic Review for Clinic
  • T6 32369030 ↗Considerations for Postacute Rehabilitation for Survivors of COVID-19
  • T6 34095290 ↗Benefits of pulmonary rehabilitation in COVID-19: a prospective observational cohort study
  • T6 35990058 ↗Depression and anxiety among children and adolescents pre and post COVID-19: A comparative meta-anal
  • T6INDIRECT 35533528 ↗Effects of mental health interventions among people hospitalized with COVID-19 infection: A systemat
  • T1 38807958 ↗Evaluating qigong as integrative support for COVID-19 and Long-COVID-19 rehabilitation: a systematic
  • T6INDIRECT 37091719 ↗Late-life depression: Epidemiology, phenotype, pathogenesis and treatment before and during the COVI
  • T6INDIRECT 38925790 ↗Neuroimmune recognition and regulation in the respiratory system
  • T6INDIRECT 37577106 ↗The use of complementary and alternative medicine for the treatment of gastrointestinal symptoms in
  • T6INDIRECT 35966751 ↗Complementary and Alternative Medicine for Long COVID: Scoping Review and Bibliometric Analysis
  • T6 36575646 ↗What can we learn from the Baduanjin rehabilitation as COVID-19 treatment?: A narrative review
  • T6 41366804 ↗Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): diagnosis and management
  • T6 33733717 ↗Translational research on Myology and Mobility Medicine: 2021 semi-virtual PDM3 from Thermae of Euga
  • T6 39234315 ↗18&lt;sup&gt;th&lt;/sup&gt; Asian Federation of Sports Medicine Congress cum 8&lt;sup&gt;th&lt;/sup&
  • T6 37505151 ↗2023 International Conference on Life, Health and Modern Medicine
  • T6 34926835 ↗Program Abstracts from The GSA 2021 Annual Scientific Meeting, "Disruption to Transformation: Aging
  • T6 33358750 ↗Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease
  • T6 36681118 ↗Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disea
  • T6 36387947 ↗Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune F
  • T6 39220224 ↗Traditional Chinese Rehabilitation Exercise (TCRE) for Myofascial Pain: Current Evidence and Further
Reaction Time Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
5 sources
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
  • T2REGISTERED-ONLY NCT07523113 ↗ME/CFS Brain Fog: Cognitive Rehabilitation Trial
  • T6INDIRECT 40952658 ↗Effects of exergaming with a resistance component versus traditional resistance training on sarcopen
  • T6 37190625 ↗The Use of Neurofeedback in Sports Training: Systematic Review
  • T6 39727822 ↗Physical Exercise Intervention Characteristics and Outcomes in Frail and Pre-Frail Older Adults
Rehabilitation program
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
25 sources
  • T1 NCT05848518 ↗Exercise for Health in Patients With Post-acute Sequelae of COVID-19
  • T1 NCT06952127 ↗Feasibility and Preliminary Efficacy of a Group-based Telerehabilitation Program in People With Post
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T1 37725376 ↗Rehabilitation Interventions for Physical Capacity and Quality of Life in Adults With Post-COVID-19
  • T6INDIRECT 34339806 ↗Psychiatric and neuropsychiatric sequelae of COVID-19 - A systematic review
  • T6INDIRECT 34592585 ↗Telehealth utilization during the Covid-19 pandemic: A systematic review
  • T1 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T1 35265644 ↗Effect of Pulmonary Rehabilitation for Patients With Post-COVID-19: A Systematic Review and Meta-Ana
  • T1 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6INDIRECT 37155736 ↗Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019
  • T1 35409815 ↗Cardiopulmonary Rehabilitation in Long-COVID-19 Patients with Persistent Breathlessness and Fatigue:
  • T6INDIRECT 33831043 ↗Post-COVID-19 syndrome among symptomatic COVID-19 patients: A prospective cohort study in a tertiary
  • T6 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6INDIRECT 34710173 ↗Impact of Covid-19 on health-related quality of life of patients: A structured review
  • T6INDIRECT 35493431 ↗Long COVID and neuropsychiatric manifestations (Review)
  • T6INDIRECT 34218857 ↗Post-COVID-19 Syndrome (Long Haul Syndrome): Description of a Multidisciplinary Clinic at Mayo Clini
  • T6 32529595 ↗Post-COVID-19 global health strategies: the need for an interdisciplinary approach
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 37457901 ↗Post-COVID cognitive dysfunction: current status and research recommendations for high risk populati
  • T6 35566253 ↗The Pathophysiology of Long COVID throughout the Renin-Angiotensin System
  • T6 34870247 ↗Neurological consequences of COVID-19 and brain related pathogenic mechanisms: A new challenge for n
  • T6 36836568 ↗Long COVID: Clinical Framing, Biomarkers, and Therapeutic Approaches
  • T6 34067776 ↗Post-COVID-19 Syndrome and the Potential Benefits of Exercise
  • T6 34390682 ↗Post-COVID-19 Tachycardia Syndrome: A Distinct Phenotype of Post-Acute COVID-19 Syndrome
Repetitive Transcranial Magnetic Stimulation
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
26 sources
  • T1REGISTERED-ONLY NCT07278206 ↗Brain Stimulation in Long COVID
  • T6INDIRECT 38329083 ↗Efficacy and safety of transcranial magnetic stimulation on cognition in mild cognitive impairment,
  • T6INDIRECT 39388006 ↗Gray matter and cognitive alteration related to chronic obstructive pulmonary disease patients: comb
  • T6INDIRECT 34752489 ↗A mixed-methods systematic review of post-viral fatigue interventions: Are there lessons for long Co
  • T6INDIRECT 39384321 ↗Systematic review of interventions for mental health, cognition and psychological well-being in long
  • T1 36129719 ↗Effectiveness of Standard Sequential Bilateral Repetitive Transcranial Magnetic Stimulation vs Bilat
  • T1 38228914 ↗Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for
  • T6INDIRECT 36455453 ↗Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABA<sub>B</sub>-ergic activity and cor
  • T6INDIRECT 35974039 ↗Improving taste sensitivity in healthy adults using taste recall training: a randomized controlled t
  • T6INDIRECT 40094666 ↗Donepezil for Fatigue and Psychological Symptoms in Post-COVID-19 Condition: A Randomized Clinical T
  • T6INDIRECT 36610206 ↗Real world research on transcranial magnetic stimulation treatment strategies for neuropsychiatric s
  • T6 35734582 ↗Non-invasive brain stimulation and neuroenhancement
  • T6 33537521 ↗Potential for increased prevalence of neuropathic pain after the COVID-19 pandemic
  • T6INDIRECT 37004143 ↗A 30-Year-Old Woman with an 8-Week History of Anxiety, Depression, Insomnia, and Mild Cognitive Impa
  • T6INDIRECT 36831861 ↗Depression in Major Neurodegenerative Diseases and Strokes: A Critical Review of Similarities and Di
  • T6INDIRECT 39744683 ↗Photobiomodulation: shining a light on depression
  • T6INDIRECT 41688232 ↗Clinical utility and prospective of TMS-EEG: Updated review from an international expert group
  • T6 37372912 ↗What Do We Know about Nociplastic Pain?
  • T6 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
  • T6 36225892 ↗A comprehensive review of transcranial magnetic stimulation in secondary dementia
  • T6 39519182 ↗Understanding Endothelial Dysfunction and Its Role in Ischemic Stroke After the Outbreak of Recanali
  • T6 37304012 ↗Matrix disequilibrium in Alzheimer's disease and conditions that increase Alzheimer's disease risk
  • T6 33324324 ↗Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19
  • T6 38367046 ↗Artificial intelligence in neurology: opportunities, challenges, and policy implications
  • T6 35720084 ↗Dysautonomia in COVID-19 Patients: A Narrative Review on Clinical Course, Diagnostic and Therapeutic
  • T6 38944141 ↗Stress and Inflammation Target Dorsolateral Prefrontal Cortex Function: Neural Mechanisms Underlying
Rice Protein Powder with Vitamin C
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT06967428 ↗Effect of Metabolic Modulation on a Post-acute COVID-19 Vaccination Syndrome (PACVS) Cohort
Ritonavir
T1
T1 — RCT in LC/PASC/PACVS
Harm signalLong COVID
28 sources
  • T1 NCT05576662 ↗Paxlovid for Treatment of Long Covid
  • T1HARM NCT05668091 ↗A Decentralized, Randomized Phase 2 Efficacy and Safety Study of Nirmatrelvir/Ritonavir in Adults wi
  • T1 NCT05965726 ↗RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms
  • T6INDIRECT 33549624 ↗COVID-19 in immunocompromised patients: A systematic review of cancer, hematopoietic cell and solid
  • T6INDIRECT 33426733 ↗Cerebral venous thrombosis and severe acute respiratory syndrome coronavirus-2 infection: A systemat
  • T6INDIRECT 34396514 ↗Systemic corticosteroids for the treatment of COVID-19
  • T6INDIRECT 34318930 ↗Ivermectin for preventing and treating COVID-19
  • T6INDIRECT 34452974 ↗Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalitis Following COVID-19: Sys
  • T6INDIRECT 34386902 ↗Association of CNS demyelination and COVID-19 infection: an updated systematic review
  • T6INDIRECT 33036570 ↗Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
  • T6INDIRECT 32454187 ↗Review of trials currently testing treatment and prevention of COVID-19
  • T1 38848477 ↗Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection: The S
  • T1 37276589 ↗Effectiveness of COVID-19 Treatment With Nirmatrelvir-Ritonavir or Molnupiravir Among U.S. Veterans:
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 32201335 ↗Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID
  • T6INDIRECT 33723416 ↗The first 12 months of COVID-19: a timeline of immunological insights
  • T6INDIRECT 33856918 ↗COVID-19 and Cardiovascular Disease: From Bench to Bedside
  • T6INDIRECT 33609255 ↗A Review of Persistent Post-COVID Syndrome (PPCS)
  • T6INDIRECT 32857878 ↗Thrombosis in COVID-19
  • T6INDIRECT 33219837 ↗Severe COVID-19, multisystem inflammatory syndrome in children, and Kawasaki disease: immunological
  • T6INDIRECT 33595463 ↗COVID-19 and Eye: A Review of Ophthalmic Manifestations of COVID-19
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 33965003 ↗The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 35271343 ↗The immunology and immunopathology of COVID-19
  • T6 33892403 ↗Long COVID: An overview
  • T6 33431578 ↗Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients
Routine care and book
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06004362 ↗Complementary and Integrative Medicine as an Online Intervention in Patients With Post-covid Syndrom
Selzentry
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
6 sources
  • T1REGISTERED-ONLY NCT06511063 ↗Antiviral Clinical Trial for Long Covid-19
  • T6 39947217 ↗Targeting the SARS-CoV-2 reservoir in long COVID
  • T6 40559563 ↗Digestive Manifestations of Post-COVID-19: A Focus on Therapeutic Strategies
  • T6 36678799 ↗Modulating Immune Response in Viral Infection for Quantitative Forecasts of Drug Efficacy
  • T6 42325367 ↗Long COVID: current research and future directions
  • T6 PMC12982061 ↗Candidate treatments for long COVID: a narrative review of expert and patient-driven priorities
Sirolimus
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
20 sources
  • T1REGISTERED-ONLY NCT04948203 ↗Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID
  • T6INDIRECT 38105461 ↗Outpatient randomized controlled trials to reduce COVID-19 hospitalization: Systematic review and me
  • T6INDIRECT 36029185 ↗Prevalence of NSAID use among people with COVID-19 and the association with COVID-19-related outcome
  • T6INDIRECT 36473651 ↗Efficacy and safety of COVID-19 vaccines
  • T6INDIRECT 34679203 ↗Antibiotics for the treatment of COVID-19
  • T6INDIRECT 37175556 ↗Efficacy of Pirfenidone and Nintedanib in Interstitial Lung Diseases Other than Idiopathic Pulmonary
  • T6INDIRECT 36111511 ↗Heart failure during the COVID-19 pandemic: clinical, diagnostic, management, and organizational dil
  • T6INDIRECT 36786873 ↗A systematic review of the incidence, management and prognosis of new-onset autoimmune connective ti
  • T6INDIRECT 34837648 ↗Comparing efficacy and safety of different doses of dexamethasone in the treatment of COVID-19: a th
  • T6INDIRECT 33084029 ↗Seroprevalence of anti-SARS-CoV-2 antibodies in COVID-19 patients and healthy volunteers up to 6 mon
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 33586189 ↗COVID-19: immunopathology, pathophysiological mechanisms, and treatment options
  • T6INDIRECT 34375047 ↗Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Trea
  • T6INDIRECT 34793455 ↗COVID-19-associated mucormycosis: Evidence-based critical review of an emerging infection burden dur
  • T6INDIRECT 33890986 ↗Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-
  • T6 37060495 ↗Pathological angiogenesis: mechanisms and therapeutic strategies
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 37018987 ↗Paxlovid (Nirmatrelvir/Ritonavir): A new approach to Covid-19 therapy?
Smell Training
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
23 sources
  • T1REGISTERED-ONLY NCT05855369 ↗Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 35957578 ↗Qualitative Olfactory Dysfunction and COVID-19: An Evidence-Based Review with Recommendations for th
  • T6INDIRECT 36062970 ↗Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 34456675 ↗Steroids and Olfactory Training for Postviral Olfactory Dysfunction: A Systematic Review
  • T6INDIRECT 36063364 ↗Interventions for the prevention of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 37531338 ↗Effect of any form of steroids in comparison with that of other medications on the duration of olfac
  • T6INDIRECT 36976171 ↗Treatment of Olfactory Disorders After SARS - CoViD 2 Virus Infection
  • T6INDIRECT 41555643 ↗The APOLLO trial: a proof-of-concept study for vitamin A nasal drops in COVID-19-related postinfecti
  • T6 35373533 ↗International consensus statement on allergy and rhinology: Olfaction
  • T6 32854169 ↗Management of new onset loss of sense of smell during the COVID-19 pandemic - BRS Consensus Guidelin
  • T6 34559820 ↗Altered smell and taste: Anosmia, parosmia and the impact of long Covid-19
  • T6 38898278 ↗Human SARS-CoV-2 challenge uncovers local and systemic response dynamics
  • T6INDIRECT 37496529 ↗Efficacy of Stellate Ganglion Block in Treating Long-Term COVID-19-Related Olfactory and Gustatory D
  • T6INDIRECT 36949968 ↗A Review of Stellate Ganglion Block as an Adjunctive Treatment Modality
  • T6 35894511 ↗COVID-19 and olfactory dysfunction: a looming wave of dementia?
  • T6 35874953 ↗Revealing the mystery of persistent smell loss in Long COVID patients
  • T6 37366867 ↗Post-COVID-19 Anosmia and Therapies: Stay Tuned for New Drugs to Sniff Out
  • T6 34191699 ↗SARS-Cov-2 Damage on the Nervous System and Mental Health
  • T6 36835589 ↗Chemosensory Ability and Sensitivity in Health and Disease: Epigenetic Regulation and COVID-19
  • T6 35448042 ↗Changes in the Intranetwork and Internetwork Connectivity of the Default Mode Network and Olfactory
  • T6 36196612 ↗Preliminary Guidelines for the Clinical Evaluation and Management of Long COVID
  • T6 36180640 ↗Neurological consequences of COVID-19
Sodium Citrate
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
26 sources
  • T1REGISTERED-ONLY NCT06204432 ↗Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T6INDIRECT 35957578 ↗Qualitative Olfactory Dysfunction and COVID-19: An Evidence-Based Review with Recommendations for th
  • T6INDIRECT 34456675 ↗Steroids and Olfactory Training for Postviral Olfactory Dysfunction: A Systematic Review
  • T6INDIRECT 38459338 ↗A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
  • T6INDIRECT 36507615 ↗Use of platelet-rich plasma for COVID-19-related olfactory loss: a randomized controlled trial
  • T1 35942688 ↗Effect of Sodium Gluconate on Decreasing Elevated Nasal Calcium and Improving Olfactory Function Pos
  • T6INDIRECT 40504522 ↗Stellate Ganglion Block for the Treatment of COVID-19-Induced Parosmia: A Randomized Clinical Trial
  • T6INDIRECT 39763448 ↗Treatment with Sulodexide Downregulates Biomarkers for Endothelial Dysfunction in Convalescent COVID
  • T6INDIRECT 33999778 ↗Distinct phenotypes of platelet, monocyte, and neutrophil activation occur during the acute and conv
  • T6 32526206 ↗SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract
  • T6 34425843 ↗Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accomp
  • T6 37848036 ↗Serotonin reduction in post-acute sequelae of viral infection
  • T6INDIRECT 35373533 ↗International consensus statement on allergy and rhinology: Olfaction
  • T6INDIRECT 36148558 ↗Neurological post-acute sequelae of SARS-CoV-2 infection
  • T6INDIRECT 34870148 ↗Pathophysiology and possible treatments for olfactory-gustatory disorders in patients affected by CO
  • T6INDIRECT 37388279 ↗Long COVID: Complications, Underlying Mechanisms, and Treatment Strategies
  • T6INDIRECT 35870428 ↗COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis
  • T6INDIRECT 35867861 ↗SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction
  • T6 29520143 ↗Nanotechnology-based drug delivery systems for control of microbial biofilms: a review
  • T6 35365631 ↗Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates
  • T6 34087216 ↗Physical phenotype of blood cells is altered in COVID-19
  • T6 34021148 ↗Peripheral and lung resident memory T cell responses against SARS-CoV-2
  • T6 36131342 ↗Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows m
  • T6 29472725 ↗An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and bio
  • T6 34328172 ↗SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microcl
Solriamfetol
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
11 sources
  • T1 NCT06404086 ↗RECOVER-SLEEP: Platform Protocol
  • T1 NCT06404099 ↗RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)
  • T6 39125722 ↗Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detectio
  • T6 36313516 ↗Sleep medicine: Practice, challenges and new frontiers
  • T6 40046430 ↗Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechan
  • T6 35887329 ↗Proteomic Biomarkers of the Apnea Hypopnea Index and Obstructive Sleep Apnea: Insights into the Path
  • T6 40261198 ↗Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID
  • T6INDIRECT 41054740 ↗Drug Interactions With Excessive Daytime Sleepiness Treatments
  • T6INDIRECT 36454442 ↗Abstracts of the 52nd Annual Conference of the Italian Society of Neurology
  • T6 34658002 ↗Current Management of Residual Excessive Daytime Sleepiness Due to Obstructive Sleep Apnea: Insights
  • T6 35035550 ↗Highlights of the ERS Lung Science Conference and Sleep and Breathing Conference 2021 and the new EC
Specific DB program/Diaphragmatic manipulation program
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06330376 ↗Diaphragmatic Breathing Exercises for Post-COVID-19 Diaphragmatic Dysfunction (DD)
Splenic Ultrasound
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
4 sources
  • T1 NCT06189066 ↗Long COVID Ultrasound Trial
  • T6 39833963 ↗Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuro
  • T6 41781173 ↗A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of
  • T6 39259857 ↗Severe Invasive Pneumococcal Disease Caused by Serotype 19A in Children Under Five Years in Tāmaki M
Structured Pacing
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
13 sources
  • T1 NCT06404047 ↗RECOVER-ENERGIZE Platform Protocol
  • T1 NCT06404073 ↗RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))
  • T6 37326700 ↗Rehabilitative interventions in patients with persistent post COVID-19 symptoms-a review of recent a
  • T6 36461167 ↗Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health stat
  • T6 38658496 ↗Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exe
  • T6 37166076 ↗Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmo
  • T6 37569053 ↗Physical Activity in Long COVID: A Comparative Study of Exercise Rehabilitation Benefits in Patients
  • T6 41213692 ↗Pursuing Reduction in Fatigue After COVID-19 via Exercise and Rehabilitation (PREFACER): a protocol
  • T6 40397936 ↗Multimodal Web-Based Telerehabilitation for Patients With Post-COVID-19 Condition: Protocol for a Ra
  • T6INDIRECT 41862909 ↗Pharmacological and non-pharmacological management of long COVID
  • T6 38612615 ↗Possible Role of Cannabis in the Management of Neuroinflammation in Patients with Post-COVID Conditi
  • T6 42214072 ↗Wearable- and Mobile App-Based Activity Pacing and Fatigue Management in Post-COVID-19 Condition: Ex
  • T6 41768410 ↗Rehabilitation strategies for long COVID: integrating human factors engineering
SuperCAP Program
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06315894 ↗Supervised Computerized Active Program for People With Post-COVID Syndrome (SuperCAP Study)
Swimming
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
25 sources
  • T1 NCT07454395 ↗Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chroni
  • T6INDIRECT 34769800 ↗Impact of the COVID-19 Pandemic on Sedentary Time and Behaviour in Children and Adults: A Systematic
  • T6INDIRECT 37359525 ↗Lipopolysaccharide-induced depression-like model in mice: meta-analysis and systematic evaluation
  • T6INDIRECT 37666869 ↗Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chr
  • T6INDIRECT 35716338 ↗SARS-CoV-2 effects on sperm parameters: a meta-analysis study
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T6INDIRECT 33284353 ↗Rehabilitation setting during and after Covid-19: An overview on recommendations
  • T6INDIRECT 37062429 ↗TFOS lifestyle: Impact of societal challenges on the ocular surface
  • T6INDIRECT 36642173 ↗A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19
  • T6INDIRECT 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 35954922 ↗The Effectiveness of a Four-Week Digital Physiotherapy Intervention to Improve Functional Capacity a
  • T6 33243837 ↗Autonomic dysfunction in 'long COVID': rationale, physiology and management strategies
  • T6 34067776 ↗Post-COVID-19 Syndrome and the Potential Benefits of Exercise
  • T6INDIRECT 33723532 ↗Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrom
  • T6INDIRECT 33735380 ↗Physical Therapy Management of an Individual With Post-COVID Syndrome: A Case Report
  • T6INDIRECT 34403043 ↗Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor's pag
  • T6INDIRECT 35307156 ↗2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocard
  • T6INDIRECT 38123343 ↗Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Dise
  • T6INDIRECT 36202135 ↗Clinical guidelines for the use of lifestyle-based mental health care in major depressive disorder:
  • T6 36876744 ↗The British Society for Sexual Medicine Guidelines on Male Adult Testosterone Deficiency, with State
  • T6 34606374 ↗Sensory Perception in Bacterial Cyclic Diguanylate Signal Transduction
  • T6 37152753 ↗Mechanistic insights into nanoparticle surface-bacterial membrane interactions in overcoming antibio
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
  • T6 36857178 ↗SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-C
  • T6 37712135 ↗Lifestyle management of hypertension: International Society of Hypertension position paper endorsed
Synbiotic IVS-1
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT06620406 ↗Synbiotic Therapy for NP-PASC
  • T6 41952158 ↗Targeting immunosenescence in lung diseases: mechanistic insights and clinical interventions
Synthetic Vitamin B1
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
TNX-102 SL
T1
T1 — RCT in LC/PASC/PACVS
Harm signalLong COVID
4 sources
  • T1HARM NCT05472090 ↗A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain A
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 40384184 ↗Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management
  • T6 37316880 ↗Long COVID: Costs for the German economy and health care and pension system
Tailored lighting Active
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
Telerehabilitation program
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
31 sources
  • T1 NCT05866224 ↗Telerehabilitation Program and Detraining in Patients With Post-COVID-19 Sequelae
  • T6INDIRECT 35908659 ↗Effect of Pulmonary Rehabilitation Approaches on Dyspnea, Exercise Capacity, Fatigue, Lung Functions
  • T1 36249181 ↗Do patients with and survivors of COVID-19 benefit from telerehabilitation? A meta-analysis of rando
  • T1 35414491 ↗Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-
  • T6INDIRECT 38214047 ↗Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation
  • T6INDIRECT 35868671 ↗Long COVID-19: The Need for an Interdisciplinary Approach
  • T1 38477069 ↗Evidence-based position paper on Physical and Rehabilitation Medicine (PRM) professional practice on
  • T6INDIRECT 36700571 ↗Effects of a home-based pulmonary rehabilitation program with and without telecoaching on health-rel
  • T1 38009852 ↗Effects of a telerehabilitation program and detraining on cardiorespiratory fitness in patients with
  • T1 38320238 ↗Educational, Exercise, and Occupational Therapy-Based Telerehabilitation Program Versus "Wait-and-Se
  • T6 33642858 ↗Pulmonary Rehabilitation in a Post-COVID-19 World: Telerehabilitation as a New Standard in Patients
  • T6 37581410 ↗Pulmonary Rehabilitation for Adults with Chronic Respiratory Disease: An Official American Thoracic
  • T6 34640447 ↗Effectiveness of a Primary Care Telerehabilitation Program for Post-COVID-19 Patients: A Feasibility
  • T6INDIRECT 36849853 ↗Could the fibromyalgia syndrome be triggered or enhanced by COVID-19?
  • T6INDIRECT 35789736 ↗The effect of exercise rehabilitation on COVID-19 outcomes: a systematic review of observational and
  • T6INDIRECT 35968401 ↗Post-COVID lung disease(s)
  • T6INDIRECT 36615087 ↗Post-Acute Sequelae of COVID-19: The Potential Role of Exercise Therapy in Treating Patients and Ath
  • T6INDIRECT 36530872 ↗Cardiopulmonary disease as sequelae of long-term COVID-19: Current perspectives and challenges
  • T6INDIRECT 33364571 ↗Pulmonary Rehabilitation in COVID-19 patients: A scoping review of current practice and its applicat
  • T4 33395048 ↗An Improvised Pulmonary Telerehabilitation Program for Postacute COVID-19 Patients Would Be Feasible
  • T6 37255115 ↗Telemedicine in healthcare access during the covid-19 pandemic: a scoping review
  • T6 36570860 ↗Full GSA 2022 Abstract Book PDF
  • T6 40986224 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2025)
  • T6 PMC11688754 ↗Full GSA 2024 Abstract Book PDF
  • T6 39252016 ↗Proceedings of the 31st European Paediatric Rheumatology Congress: part 1
  • T6 PMC9073161 ↗ESOC 2022 Abstract Book
  • T6 PMC8853075 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2021): Po
  • T6 36673555 ↗Telerehabilitation, A Viable Option in Patients with Persistent Post-COVID Syndrome: A Systematic Re
  • T6 37761716 ↗Efficacy and Safety of Respiratory Telerehabilitation in Patients with Long COVID-19: A Systematic R
  • T6 36851746 ↗Post-COVID-19 Syndrome Comprehensive Assessment: From Clinical Diagnosis to Imaging and Biochemical-
  • T6 37185117 ↗Year in Review: Long COVID and Pulmonary Rehabilitation
Telerehabilitation program based on cardiorespiratory principles
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
Temelimab /kg
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05497089 ↗Temelimab as a Disease Modifying Therapy in Patients With Neuropsychiatric Symptoms in Post-COVID 19
To Measure levels of circulating monocyte/ T cell doublets at Baseline
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT07189936 ↗Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS
To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT07189936 ↗Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS
Tonabersat
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06437223 ↗Study of Xiflam™ Treatment in Patients Post COVID-19 Infection Suffering From What is Known as Long
Traditional Chinese medicine treatment
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
12 sources
  • T1 NCT06095258 ↗A Practical RCT of TCM in the Treatment of LCOVID and Analysis of Syndrome Types and Medication Char
  • T6 36703736 ↗The pathological mechanism of the COVID-19 convalescence and its treatment with traditional Chinese
  • T6 38893693 ↗A Comprehensive Review of the Global Epidemiology, Clinical Management, Socio-Economic Impacts, and
  • T6 37243072 ↗Clinical Characteristics of Mild Patients with Breakthrough Infection of Omicron Variant in China af
  • T6 35571407 ↗Changes in inpatient admissions before and during COVID-19 outbreak in a large tertiary hospital in
  • T6 38092887 ↗Epidemiological and clinical features of SARS-CoV-2 Omicron variant infection in Quanzhou, Fujian pr
  • T6INDIRECT 38576710 ↗Acupressure: a possible therapeutic strategy for anxiety related to COVID-19: a meta-analysis of ran
  • T4 35648696 ↗COVID-19 Patients' Views and Experiences of Traditional Chinese Medicine Treatment in South Africa
  • T6INDIRECT 37505151 ↗2023 International Conference on Life, Health and Modern Medicine
  • T6 39057037 ↗Potential Protective Factors for Allergic Rhinitis Patients Infected with COVID-19
  • T6 40182854 ↗Explainable machine learning model and nomogram for predicting the efficacy of Traditional Chinese M
  • T6 40234823 ↗Follow-up of long COVID based on the definition of WHO: a multi-centre cross-sectional questionnaire
Transcutaneous Non-Invasive Vagus Nerve Stimulation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
Transcutaneous vagus nerve stimulator
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
Transfer Package
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
7 sources
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
  • T2REGISTERED-ONLY NCT07523113 ↗ME/CFS Brain Fog: Cognitive Rehabilitation Trial
  • T6INDIRECT 40310209 ↗Long COVID brain fog treatment: An early-phase randomized controlled trial of constraint-induced cog
  • T6 PPR342074 ↗Fiscal Policy Responses to COVID-19 in Danida Priority Countries in Sub-Saharan Africa
  • T6 37373305 ↗Bioengineered Enzymes and Precision Fermentation in the Food Industry
  • T6 40726475 ↗11th European Stroke Organisation Conference Abstracts - 21-23 May 2025, Helsinki, Finland
  • T6 PMC7103908 ↗Symposia
Treatment as Usual
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
44 sources
  • T1REGISTERED-ONLY NCT06928480 ↗Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotion
  • T2 NCT04593225 ↗Effectiveness of VIRTUAL SFCAMINA STUDY
  • T6INDIRECT 34964542 ↗Remote provision of breastfeeding support and education: Systematic review and meta-analysis
  • T6INDIRECT 36634261 ↗The Usability, Feasibility, Acceptability, and Efficacy of Digital Mental Health Services in the COV
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 35414491 ↗Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-
  • T6INDIRECT 34693988 ↗Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pu
  • T6INDIRECT 33326409 ↗Implementation of Telehealth Services to Assess, Monitor, and Treat Neurodevelopmental Disorders: Sy
  • T1 36695483 ↗Remdesivir for the treatment of COVID-19
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 34913421 ↗Early Intervention in Psychosis services: A systematic review and narrative synthesis of the barrier
  • T6INDIRECT 37193738 ↗Effectiveness of a telerehabilitation intervention using ReCOVery APP of long COVID patients: a rand
  • T6 35039676 ↗Immune targets for therapeutic development in depression: towards precision medicine
  • T6HARM 35727534 ↗Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment
  • T6INDIRECT 20350028 ↗The effect of mindfulness-based therapy on anxiety and depression: A meta-analytic review
  • T6INDIRECT 26730878 ↗Exercise-based cardiac rehabilitation for coronary heart disease
  • T6INDIRECT 28045199 ↗Yoga for improving health-related quality of life, mental health and cancer-related symptoms in wome
  • T6INDIRECT 30284240 ↗Psychological interventions for needle-related procedural pain and distress in children and adolesce
  • T6INDIRECT 18646067 ↗Cognitive behaviour therapy for chronic fatigue syndrome in adults
  • T6INDIRECT 26358158 ↗Exercise therapy for fatigue in multiple sclerosis
  • T6INDIRECT 31369582 ↗Helping patients help themselves: A systematic review of self-management support strategies in prima
  • T6INDIRECT 20091628 ↗Shared decision making interventions for people with mental health conditions
  • T2 17119141 ↗Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research T
  • T6INDIRECT 35654766 ↗Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a ra
  • T6 20471738 ↗Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms
  • T6 23459093 ↗The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses
  • T6INDIRECT 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6INDIRECT 35571085 ↗Oxidative Stress and Hyper-Inflammation as Major Drivers of Severe COVID-19 and Long COVID: Implicat
  • T6INDIRECT 34118499 ↗Addressing Pediatric Mental Health Using Telehealth During Coronavirus Disease-2019 and Beyond: A Na
  • T6 39363044 ↗Vagus nerve stimulation (VNS): recent advances and future directions
  • T6 38891970 ↗Human Gut Microbiota for Diagnosis and Treatment of Depression
  • T6 37795783 ↗Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood
  • T6 37713568 ↗Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epide
  • T2 23990997 ↗Mindfulness-based therapies in the treatment of somatization disorders: a systematic review and meta
  • T6INDIRECT 34770209 ↗Sleep Disorders in Cancer-A Systematic Review
  • T6INDIRECT 25365763 ↗Interoceptive dysfunction: toward an integrated framework for understanding somatic and affective di
  • T4 28052319 ↗Treatment and management of chronic fatigue syndrome/myalgic encephalomyelitis: all roads lead to Ro
  • T6 23235630 ↗Interventions to facilitate return to work in adults with adjustment disorders
  • T6 32691879 ↗Psychological interventions to foster resilience in healthcare students
  • T6 35561510 ↗How do psychologically based interventions for chronic musculoskeletal pain work? A systematic revie
  • T6 34352116 ↗Primary-level worker interventions for the care of people living with mental disorders and distress
  • T6 32296353 ↗Depression, Mindfulness, and Psilocybin: Possible Complementary Effects of Mindfulness Meditation an
  • T6 37049975 ↗The Role of Probiotics and Their Metabolites in the Treatment of Depression
  • T6 35115105 ↗Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Revi
Treatment as usual
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
21 sources
  • T1 NCT05798221 ↗Complementary Self-help Strategies for Patients With Post-COVID-19 Syndrome
  • T6 NCT05212467 ↗AIR-program and HUS Internet Therapy Compared to Treatment as Usual in Functional Disorders and Post
  • T6INDIRECT 34964542 ↗Remote provision of breastfeeding support and education: Systematic review and meta-analysis
  • T6INDIRECT 36634261 ↗The Usability, Feasibility, Acceptability, and Efficacy of Digital Mental Health Services in the COV
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 35414491 ↗Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-
  • T6INDIRECT 34693988 ↗Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pu
  • T6INDIRECT 33326409 ↗Implementation of Telehealth Services to Assess, Monitor, and Treat Neurodevelopmental Disorders: Sy
  • T1 36695483 ↗Remdesivir for the treatment of COVID-19
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 34913421 ↗Early Intervention in Psychosis services: A systematic review and narrative synthesis of the barrier
  • T6INDIRECT 37193738 ↗Effectiveness of a telerehabilitation intervention using ReCOVery APP of long COVID patients: a rand
  • T6 35039676 ↗Immune targets for therapeutic development in depression: towards precision medicine
  • T6HARM 35727534 ↗Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment
  • T6INDIRECT 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6INDIRECT 35571085 ↗Oxidative Stress and Hyper-Inflammation as Major Drivers of Severe COVID-19 and Long COVID: Implicat
  • T6INDIRECT 34118499 ↗Addressing Pediatric Mental Health Using Telehealth During Coronavirus Disease-2019 and Beyond: A Na
  • T6 39363044 ↗Vagus nerve stimulation (VNS): recent advances and future directions
  • T6 38891970 ↗Human Gut Microbiota for Diagnosis and Treatment of Depression
  • T6 37795783 ↗Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood
  • T6 37713568 ↗Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epide
Trigeminal Nerve Stimulation
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
12 sources
  • T1REGISTERED-ONLY NCT05855369 ↗Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
  • T6 38627548 ↗Corneal neuropathic pain: a review to inform clinical practice
  • T6 36501098 ↗Eating Habits and Body Weight Changes Induced by Variation in Smell and Taste in Patients with Previ
  • T6 40293510 ↗Alpha-synuclein pathology and Parkinson's disease-related olfactory dysfunctions: an update on precl
  • T6 34002281 ↗Navigating migraine care through the COVID-19 pandemic: an update
  • T6 37705568 ↗The Effect of Epipharyngeal Abrasive Therapy (EAT) on the Baroreceptor Reflex (BR)
  • T6INDIRECT 41781173 ↗A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of
  • T6INDIRECT 34488620 ↗The International Headache Congress - IHS and EHF joint congress 2021 : Virtual. 8-12 September 2021
  • T4 PMC11292956 ↗Abstracts from the 17th European Headache Congress (EHC)
  • T4 PPR634307 ↗Novel Protocol Using a Comprehensive Training ‘N’ Treatment (TNT) Approach Rapidly Reverses Olfactor
  • T6 PMC11077711 ↗Proceedings of the 101st Annual Meeting of The Physiological Society of Japan
  • T6 36350954 ↗2022 Brazilian Thoracic Association recommendations for long-term home oxygen therapy
Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
5 sources
  • T1REGISTERED-ONLY NCT06928480 ↗Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotion
  • T1 41701690 ↗Effectiveness and acceptability of the unified protocol for the transdiagnostic treatment of emotion
  • T6 40779512 ↗Preliminary feasibility and clinical utility of the Unified Protocol for the transdiagnostic treatme
  • T6 37920733 ↗Unified Protocol for the transdiagnostic treatment of emotional disorders in people with post COVID-
  • T6 41039861 ↗&lt;i&gt;Taking Control of Your Functional Cognitive Symptoms: Workbook&lt;/i&gt;-A Novel Interventi
Valacyclovir
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
22 sources
  • T1REGISTERED-ONLY NCT07597902 ↗SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction
  • T6INDIRECT 36736577 ↗Systematic review with meta-analysis of active herpesvirus infections in patients with COVID-19: Old
  • T6INDIRECT 39916377 ↗Facial Nerve Palsy Amid the SARS-CoV-2 Pandemic: A Pooled Analysis
  • T6INDIRECT 35316551 ↗A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendat
  • T6INDIRECT 37101275 ↗Viral reactivations and co-infections in COVID-19 patients: a systematic review
  • T6INDIRECT 35731363 ↗Neuropathic Pain Associated with COVID-19: a Systematic Review of Case Reports
  • T6INDIRECT 35648785 ↗Oro-facial mucocutaneous manifestations of Coronavirus Disease-2019 (COVID-19): A systematic review
  • T6INDIRECT 39390499 ↗Meningitis after COVID-19 vaccination, a systematic review of case reports and case series
  • T6INDIRECT 37735648 ↗Clinical characteristics and prognosis of temporary miller fisher syndrome following COVID-19 vaccin
  • T6INDIRECT 41562079 ↗Patient-reported improvements from use of IMC-2 alone and IMC-2 and Paxlovid&lt;sup&gt;®&lt;/sup&gt;
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 33595463 ↗COVID-19 and Eye: A Review of Ophthalmic Manifestations of COVID-19
  • T6 36899952 ↗Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome and Potential Therapeutic
  • T6INDIRECT 35716105 ↗Cutaneous manifestations following COVID-19 vaccination: A report of 25 cases
  • T6INDIRECT 36851614 ↗Persistent SARS-CoV-2 Infection, EBV, HHV-6 and Other Factors May Contribute to Inflammation and Aut
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 35214800 ↗Ocular Complications Following Vaccination for COVID-19: A One-Year Retrospective
  • T6INDIRECT 35137496 ↗COVID-19 and the peripheral nervous system. A 2-year review from the pandemic to the vaccine era
  • T6INDIRECT 34826968 ↗After the Storm: Ophthalmic Manifestations of COVID-19 Vaccines
  • T6 35925897 ↗Viruses in neurodegenerative diseases: More than just suspects in crimes
  • T6 36148238 ↗The role of virus infections in Sjögren's syndrome
  • T6 38500880 ↗The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches
Valacyclovir celecoxib dose 1
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06316843 ↗Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2
Valacyclovir celecoxib dose 2
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06316843 ↗Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2
Vericiguat Tablet
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
1 source
  • T1REGISTERED-ONLY NCT05697640 ↗Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo
Vitamin B compound
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
2 sources
  • T1 NCT05638633 ↗Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome
  • T6 38184567 ↗Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with p
Vitamin K2
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
21 sources
  • T1 NCT05356936 ↗Pilot Study of Vitamin K2 (MK-7) and Vitamin D3 Supplementation and the Effects on PASC Symptomatolo
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T1 39940457 ↗Vitamin D Deficiency Meets Hill's Criteria for Causation in SARS-CoV-2 Susceptibility, Complications
  • T1 39861434 ↗Vitamins K2 and D3 Improve Long COVID, Fungal Translocation, and Inflammation: Randomized Controlled
  • T6INDIRECT 37739466 ↗Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: a double-blin
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 36364899 ↗A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
  • T6 34680457 ↗Biomarkers and Utility of the Antioxidant Potential of Probiotic Lactobacilli and Bifidobacteria as
  • T6 39861407 ↗Vitamin D: Evidence-Based Health Benefits and Recommendations for Population Guidelines
  • T6 33469977 ↗Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Poc
  • T6 35241474 ↗Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: study protoco
  • T6INDIRECT 34684123 ↗Possible Adrenal Involvement in Long COVID Syndrome
  • T6INDIRECT 39854158 ↗Long COVID and gut microbiome: insights into pathogenesis and therapeutics
  • T6INDIRECT 39114419 ↗Knee osteonecrosis after SARS-CoV-2 infection: a systematic case-based review
  • T6INDIRECT 36008648 ↗World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2022)
  • T6INDIRECT 34748955 ↗A naturopathic treatment approach for mild and moderate COVID-19: A retrospective chart review
  • T6 37410739 ↗Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based li
  • T6 36139859 ↗Vitamin E and Metabolic Health: Relevance of Interactions with Other Micronutrients
  • T6 36978981 ↗Links between Vitamin K, Ferroptosis and SARS-CoV-2 Infection
  • T6 36671555 ↗Exogenous Players in Mitochondria-Related CNS Disorders: Viral Pathogens and Unbalanced Microbiota i
  • T6 39940312 ↗Minerals and Human Health: From Deficiency to Toxicity
Viusid Solution
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT06437210 ↗Evaluation of Treatment With Viusid in Post-COVID-19 Syndrome
Vocational Rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
24 sources
  • T1REGISTERED-ONLY NCT06095297 ↗Long COVID Brain Fog: Cognitive Rehabilitation Trial
  • T6INDIRECT 38438114 ↗Factors influencing the implementation of early discharge hospital at home and admission avoidance h
  • T6INDIRECT 41062137 ↗Return to work with long COVID: a rapid review of support and challenges
  • T1 41039517 ↗Return to work for people with chronic health conditions after medical or vocational rehabilitation
  • T6INDIRECT 42168956 ↗Factors influencing work ability and return-to-work in individuals affected by post-COVID: a systema
  • T1 39614629 ↗Effectiveness of early vocational rehabilitation versus usual care to support RETurn to work after s
  • T6INDIRECT 42261574 ↗Impact of Tailored Interventions on Suicidal Ideation Recovery: Addressing Hopelessness Among Econom
  • T6 34678213 ↗Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care
  • T6 37795783 ↗Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood
  • T6 32470131 ↗The COVID-19 rehabilitation pandemic
  • T6 34346558 ↗Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fati
  • T6 36169154 ↗Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of aut
  • T6MIXED 35580970 ↗LOng COvid Multidisciplinary consortium Optimising Treatments and servIces acrOss the NHS (LOCOMOTIO
  • T6INDIRECT 39429966 ↗COVID-19 and multiple sclerosis: challenges and lessons for patient care
  • T6INDIRECT 36588206 ↗Rhino-orbito-cerebral mucormycosis and its resurgence during COVID-19 pandemic: A review
  • T6INDIRECT 38616276 ↗What is quality in long covid care? Lessons from a national quality improvement collaborative and mu
  • T6INDIRECT 34899105 ↗What does Success Look Like for Leaders of Integrated Health and Social Care Systems? a Realist Revi
  • T6INDIRECT 34160029 ↗Apparent Discordance Between the Epidemiology of COVID-19 and Recommended Outcomes and Treatments: A
  • T6 35741569 ↗Cognitive Remediation in Psychiatric Disorders: State of the Evidence, Future Perspectives, and Some
  • T6 35252582 ↗Main Abstracts
  • T6 41358855 ↗Canadian Adaptation of REVEAL(OT) for Chronic Pain Management: Rapid Qualitative Analysis Results
  • T6 37915105 ↗Abstracts of Scientific Presentations: 2023 AALAS National Meeting, Salt Lake City, Utah
  • T6 33988148 ↗The times they are a-changin: implementing new psychiatric rehabilitation models within a community
  • T6 PMC11391898 ↗ESOC 2023 Abstract Book
Vortioxetine
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
24 sources
  • T1 NCT05047952 ↗Vortioxetine for Post-COVID-19 Condition
  • T6INDIRECT 39603702 ↗Interventions for the management of long covid (post-covid condition): living systematic review
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 39384321 ↗Systematic review of interventions for mental health, cognition and psychological well-being in long
  • T6INDIRECT 38228914 ↗Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for
  • T1 37936330 ↗Vortioxetine for the treatment of post-COVID-19 condition: a randomized controlled trial
  • T6INDIRECT 39356507 ↗Lithium Aspartate for Long COVID Fatigue and Cognitive Dysfunction: A Randomized Clinical Trial
  • T6INDIRECT 38520501 ↗Assessing the Effects of Metabolic Disruption, Body Mass Index and Inflammation on Depressive Sympto
  • T6INDIRECT 41212544 ↗Evaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial
  • T6INDIRECT 38860901 ↗Association between fatigue and depressive symptoms in persons with post-COVID-19 condition: a post
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 37451743 ↗Faecalibacterium: a bacterial genus with promising human health applications
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 36831861 ↗Depression in Major Neurodegenerative Diseases and Strokes: A Critical Review of Similarities and Di
  • T6INDIRECT 37091719 ↗Late-life depression: Epidemiology, phenotype, pathogenesis and treatment before and during the COVI
  • T6INDIRECT 36532316 ↗Antidepressants with anti-inflammatory properties may be useful in long COVID depression
  • T6INDIRECT 37388279 ↗Long COVID: Complications, Underlying Mechanisms, and Treatment Strategies
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 37457901 ↗Post-COVID cognitive dysfunction: current status and research recommendations for high risk populati
  • T6 35943535 ↗Selective serotonin reuptake inhibitor (SSRI) antidepressants reduce COVID-19 infection: prospects f
  • T6 40141784 ↗Neuropsychiatric Manifestations of Long COVID-19: A Narrative Review of Clinical Aspects and Therape
  • T6 38755657 ↗Individualized strategies for depression: narrative review of clinical profiles responsive to vortio
  • T6 35874958 ↗Long COVID and its Management
Walking
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
23 sources
  • T1REGISTERED-ONLY NCT06928116 ↗Heat thErapy And mobiLity in COVID-19 Survivors
  • T6INDIRECT 36215063 ↗Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symp
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T6INDIRECT 33925784 ↗Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)-A Systemic Review and Com
  • T6INDIRECT 33977626 ↗Frequency, signs and symptoms, and criteria adopted for long COVID-19: A systematic review
  • T6INDIRECT 35866452 ↗Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection
  • T6INDIRECT 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T6INDIRECT 34017846 ↗Post-COVID-19 Syndrome: The Persistent Symptoms at the Post-viral Stage of the Disease. A Systematic
  • T6INDIRECT 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 33306721 ↗Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 33753937 ↗Post-acute COVID-19 syndrome
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34687662 ↗The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future
  • T6INDIRECT 33146552 ↗Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease.
  • T6INDIRECT 32475821 ↗The Stanford Hall consensus statement for post-COVID-19 rehabilitation
  • T6 32529595 ↗Post-COVID-19 global health strategies: the need for an interdisciplinary approach
  • T6 32422178 ↗Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy
  • T6 35304603 ↗Exerkines in health, resilience and disease
  • T6 33857435 ↗Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuro
  • T6 29155571 ↗Oxygen Activation by Cu LPMOs in Recalcitrant Carbohydrate Polysaccharide Conversion to Monomer Suga
Wearable device
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
28 sources
  • T1REGISTERED-ONLY NCT05741112 ↗The Long COVID-19 Wearable Device Study
  • T6INDIRECT 38791798 ↗Changes in Sleep Duration and Sleep Timing in the General Population from before to during the First
  • T1 34502679 ↗The Rise of Wearable Devices during the COVID-19 Pandemic: A Systematic Review
  • T6INDIRECT 34693988 ↗Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pu
  • T1 37222916 ↗Sensitivity and Specificity of Wearables for Atrial Fibrillation in Elderly Populations: A Systemati
  • T6INDIRECT 37100544 ↗Readiness for implementation of novel digital health interventions for postoperative monitoring: a s
  • T1 36768002 ↗Self-Management of Subclinical Common Mental Health Disorders (Anxiety, Depression and Sleep Disorde
  • T6INDIRECT 34831725 ↗The Development of Telemedicine and eHealth in Surgery during the SARS-CoV-2 Pandemic
  • T6INDIRECT 36673664 ↗The Impact of SARS-CoV-2 Infection on Heart Rate Variability: A Systematic Review of Observational S
  • T6INDIRECT 35113860 ↗The development and pilot testing of a behavioral activation-based treatment for depressed mood and
  • T6 37117704 ↗Wearable chemical sensors for biomarker discovery in the omics era
  • T6 37373940 ↗A Review of the Role of Artificial Intelligence in Healthcare
  • T6 34505369 ↗The growing field of digital psychiatry: current evidence and the future of apps, social media, chat
  • T6INDIRECT 34199831 ↗Integrating Digital Technologies and Public Health to Fight Covid-19 Pandemic: Key Technologies, App
  • T6INDIRECT 32823223 ↗Unlocking challenges and opportunities presented by COVID-19 pandemic for cross-cutting disruption i
  • T4 38958517 ↗Revolutionary Point-of-Care Wearable Diagnostics for Early Disease Detection and Biomarker Discovery
  • T6INDIRECT 36074973 ↗Sinus Tachycardia: a Multidisciplinary Expert Focused Review
  • T6INDIRECT 33648821 ↗Health-related quality of life of hospitalized COVID-19 survivors: An initial exploration in Nanning
  • T6 37705603 ↗Artificial intelligence in clinical medicine: catalyzing a sustainable global healthcare paradigm
  • T6 35584269 ↗A Concept Development for the Symptom Science Model 2.0
  • T6 36671900 ↗Role of Wearable Sensing Technology to Manage Long COVID
  • T6 35084716 ↗Multiomics Analysis-Based Biomarkers in Diagnosis of Polycystic Ovary Syndrome
  • T6 40997277 ↗Next-Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiolog
  • T6 34297318 ↗Abstracts from the 2021 Annual Meeting of the Society of General Internal Medicine
  • T6 34713021 ↗Wearable Sensors for COVID-19: A Call to Action to Harness Our Digital Infrastructure for Remote Pat
  • T6 34451032 ↗Review of Wearable Devices and Data Collection Considerations for Connected Health
  • T6 33372894 ↗Promotion of Physical Activity in Older People Using mHealth and eHealth Technologies: Rapid Review
  • T6 37799217 ↗Reimagining Healthcare: Unleashing the Power of Artificial Intelligence in Medicine
Western medicine treatment
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
13 sources
  • T1 NCT06095258 ↗A Practical RCT of TCM in the Treatment of LCOVID and Analysis of Syndrome Types and Medication Char
  • T1 34715330 ↗Guidelines on the treatment with integrated traditional Chinese medicine and western medicine for se
  • T6 39220224 ↗Traditional Chinese Rehabilitation Exercise (TCRE) for Myofascial Pain: Current Evidence and Further
  • T6 38571669 ↗Guideline for the Management of Diabetes Mellitus in the Elderly in China (2024 Edition)
  • T6 38335408 ↗The impact of "long COVID" on menstruation in Chinese female college students and the intervention o
  • T6 40395923 ↗Treatment Strategy for Long COVID Based on Traditional Chinese Medicine
  • T6INDIRECT 40696628 ↗Facial edema after covid-19 ameliorated by acupuncture: A CARE-compliant case report
  • T6INDIRECT 37802610 ↗Acupuncture as a therapeutic intervention for post-COVID-19 vaccination urticaria: a systematic revi
  • T4 PMC12163242 ↗Publication Only
  • T4 PMC10586546 ↗Platform Abstracts
  • T6 41282609 ↗Mechanistic insights into traditional Chinese medicine for viral pneumonia treatment: signaling path
  • T6 41496055 ↗Bibliometric analysis of research on traditional Chinese medicine for prevention and treatment of my
  • T6 39403141 ↗Traditional clinical symptoms and signs: Kampo pattern diagnosis in modern gastrointestinal disease
Xltranplus, Xltran
T1
T1 — RCT in LC/PASC/PACVS
WithdrawnLong COVID
1 source
  • T1WITHDRAWN NCT05467904 ↗Double-Blind Randomized Placebo-Controlled Trial of a Proprietary Full Hemp Flower Formulation for L
Yoga Therapy
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
20 sources
  • T1REGISTERED-ONLY NCT05890599 ↗Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19
  • T6INDIRECT 42111473 ↗Yoga interventions and randomized controlled trials: key issues and the centered impact on sedentary
  • T6INDIRECT 40189695 ↗Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6HARM 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
  • T6 36525872 ↗Yoga for COVID-19: An ancient practice for a new condition - A literature review
  • T6 34305355 ↗Role of Ayurveda and Yoga-Based lifestyle in the COVID-19 pandemic - A narrative review
  • T6 39812093 ↗International perspective on social cognition in schizophrenia: current stage and the next steps
  • T6 41130694 ↗Yoga versus health education for persistent fatigue in patients with post-COVID-19 syndrome: protoco
  • T6INDIRECT 38157657 ↗Usefulness of Yoga in the management of tinnitus during COVID-19: A narrative review
  • T6INDIRECT 38111478 ↗Arts therapies for mental disorders in COVID-19 patients: a comprehensive review
  • T6INDIRECT 39569098 ↗Validation and efficacy of a tele-yoga intervention for improving psychological stress, mental healt
  • T6INDIRECT 37292532 ↗The Effectiveness of Adjuvant Attangaogam (Athanam) Yoga Asana-Pranayamam Practices With Regard to B
  • T6INDIRECT 34628664 ↗Apart, but still together: Separated parents living in limbo during COVID-19
  • T4 PMC13111897 ↗2026 International Congress Abstract Supplement
  • T4 PMC11873978 ↗Lifestyle Medicine 2024 Annual Conference Research Abstracts
  • T6 34191699 ↗SARS-Cov-2 Damage on the Nervous System and Mental Health
  • T6 35645588 ↗COVID 19 pandemic challenges and their management: A review of medicines, vaccines, patents and clin
  • T6 PMC12625850 ↗10th International Conference on Behavioral Addictions (ICBA 2025) July 7–9, 2025, Nantes, France
  • T6 35941050 ↗A century of 'The science of yoga' (1921-2021): Revival, renewal and renaissance
accelerated intermittent theta burst stimulation
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
6 sources
  • T1REGISTERED-ONLY NCT06940609 ↗Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation
  • T6HARM 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
  • T6 41688232 ↗Clinical utility and prospective of TMS-EEG: Updated review from an international expert group
  • T6 40584527 ↗Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated
  • T6 PMC11932181 ↗ANCIPS – 2025 – E-POSTERS
  • T6 PMC10729596 ↗ACNP 62nd Annual Meeting: Poster Abstracts P251 – P500
acupuncture
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
54 sources
  • T1 NCT05890508 ↗Electro-acupuncture for Long Covid Neuropsychiatric Symptoms
  • T1 NCT05212688 ↗Randomised Study to Investigate the Effectiveness of Acupuncture for the Relief of Long COVID-19 Rel
  • T1REGISTERED-ONLY NCT07357688 ↗The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/C
  • T2 NCT01534130 ↗Acupuncture for the Sleep Disorder of Chronic Fatigue Syndrome
  • T2 NCT01907711 ↗Clinical Trial to Evaluate the Effectiveness of Acupuncture as a Treatment in Patients Diagnosed Wit
  • T2 NCT02924831 ↗High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T6INDIRECT 35265644 ↗Effect of Pulmonary Rehabilitation for Patients With Post-COVID-19: A Systematic Review and Meta-Ana
  • T6INDIRECT 39603702 ↗Interventions for the management of long covid (post-covid condition): living systematic review
  • T6INDIRECT 35893864 ↗The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musc
  • T6INDIRECT 34752489 ↗A mixed-methods systematic review of post-viral fatigue interventions: Are there lessons for long Co
  • T6INDIRECT 36642173 ↗A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19
  • T6INDIRECT 34425929 ↗Impact of olfactory dysfunction on quality of life in coronavirus disease 2019 patients: a systemati
  • T6INDIRECT 29544455 ↗Identification, description and appraisal of generic PROMs for primary care: a systematic review
  • T6INDIRECT 35489367 ↗An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms follow
  • T6INDIRECT 35416437 ↗Qingjin Yiqi granules for post-COVID-19 condition: A randomized clinical trial
  • T6 35176758 ↗Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
  • T6 37402746 ↗TRP (transient receptor potential) ion channel family: structures, biological functions and therapeu
  • T6INDIRECT 22197740 ↗Neuroimaging of the periaqueductal gray: state of the field
  • T6INDIRECT 30284240 ↗Psychological interventions for needle-related procedural pain and distress in children and adolesce
  • T6INDIRECT 18646067 ↗Cognitive behaviour therapy for chronic fatigue syndrome in adults
  • T6INDIRECT 21833945 ↗Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome
  • T6INDIRECT 29652088 ↗Non-invasive brain stimulation techniques for chronic pain
  • T6INDIRECT 29370149 ↗A Systematic Review and Meta-Analysis of Mindfulness-Based (Baduanjin) Exercise for Alleviating Musc
  • T6INDIRECT 24881045 ↗Bias due to lack of patient blinding in clinical trials. A systematic review of trials randomizing p
  • T6INDIRECT 34770209 ↗Sleep Disorders in Cancer-A Systematic Review
  • T6INDIRECT 29710099 ↗Effect of Pain Neuroscience Education Combined With Cognition-Targeted Motor Control Training on Chr
  • T6INDIRECT 19597976 ↗"Maybe I made up the whole thing": placebos and patients' experiences in a randomized controlled tri
  • T6 29462012 ↗Neuroinflammation and Central Sensitization in Chronic and Widespread Pain
  • T6 29876878 ↗Role of the Prefrontal Cortex in Pain Processing
  • T6INDIRECT 36174032 ↗Post-acute sequelae of COVID-19 symptom phenotypes and therapeutic strategies: A prospective, observ
  • T6INDIRECT 34682909 ↗Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): An Overview
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 37298527 ↗Neurodegenerative and Neurodevelopmental Diseases and the Gut-Brain Axis: The Potential of Therapeut
  • T6INDIRECT 35449490 ↗Association of mast-cell-related conditions with hypermobile syndromes: a review of the literature
  • T6INDIRECT 34607799 ↗Recommendations for the recognition, diagnosis, and management of long COVID: a Delphi study
  • T6 38152837 ↗Engineered Exosome for Drug Delivery: Recent Development and Clinical Applications
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 36174571 ↗Bioelectronic medicine: Preclinical insights and clinical advances
  • T6 33441072 ↗PTSD in the COVID-19 Era
  • T6 37372912 ↗What Do We Know about Nociplastic Pain?
  • T6 35198136 ↗Neurological manifestations of long-COVID syndrome: a narrative review
  • T6 37840685 ↗Current challenges and potential solutions to the use of digital health technologies in evidence gen
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
  • T6 41092926 ↗Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life e
  • T6INDIRECT 12830308 ↗Patients presenting with somatic complaints: epidemiology, psychiatric comorbidity and management
  • T6INDIRECT 26267006 ↗Physical exercise as non-pharmacological treatment of chronic pain: Why and when
  • T6INDIRECT 26330672 ↗Chronic Pain: Where the Body Meets the Brain
  • T6 23235630 ↗Interventions to facilitate return to work in adults with adjustment disorders
  • T6 24239063 ↗The neuroimmune basis of fatigue
  • T6 29357856 ↗Clinical relevance of contextual factors as triggers of placebo and nocebo effects in musculoskeleta
  • T6 29487504 ↗Potential Mechanisms Underlying Centralized Pain and Emerging Therapeutic Interventions
  • T6 25573802 ↗Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogr
  • T6 24944467 ↗Irritable bowel syndrome: pathogenesis, diagnosis, treatment, and evidence-based medicine
advice literature with naturopathy
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05289154 ↗Acupressure and Qigong in Chronic Fatigue Post COVID-19.
amantadine
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
22 sources
  • T1 NCT05667077 ↗The Effect of Amantadine on Post-COVD-19 Fatigue
  • T1 NCT06055244 ↗Amantadine Therapy for Cognitive Impairment in Long COVID
  • T6INDIRECT 38459000 ↗Possible temporal relationship between SARS-CoV-2 infection and anti-NMDA receptor encephalitis: a m
  • T6INDIRECT 40047167 ↗Adverse events associated with monoclonal antibodies used for treatment of COVID-19: A systematic re
  • T1 38228731 ↗A randomized open-label clinical trial on the effect of Amantadine on post Covid 19 fatigue
  • T6INDIRECT 40730806 ↗Intermittent fasting and a no-sugar diet for Long COVID symptoms: a randomized crossover trial
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 36776881 ↗The development of COVID-19 treatment
  • T6 32885037 ↗COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside
  • T6 33755344 ↗Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 "long haulers"
  • T6 34346558 ↗Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fati
  • T6INDIRECT 36464706 ↗Small molecules in the treatment of COVID-19
  • T6INDIRECT 36717892 ↗Links between COVID-19 and Parkinson's disease/Alzheimer's disease: reciprocal impacts, medical care
  • T6INDIRECT 34942956 ↗Can SARS-CoV-2 Infection Lead to Neurodegeneration and Parkinson's Disease?
  • T6INDIRECT 35216358 ↗Kidney Injury in COVID-19: Epidemiology, Molecular Mechanisms and Potential Therapeutic Targets
  • T6INDIRECT 39897928 ↗SARS-CoV-2 drug resistance and therapeutic approaches
  • T6INDIRECT 37388279 ↗Long COVID: Complications, Underlying Mechanisms, and Treatment Strategies
  • T6INDIRECT 35861926 ↗Therapeutic Approaches to the Neurologic Manifestations of COVID-19
  • T6 33240091 ↗Challenges for Drug Repurposing in the COVID-19 Pandemic Era
  • T6 38699242 ↗Macrophage based drug delivery: Key challenges and strategies
  • T6 35698330 ↗A state-of-the-art review on fucoidan as an antiviral agent to combat viral infections
  • T6 32846164 ↗COVID-19: Pathophysiology, treatment options, nanotechnology approaches, and research agenda to comb
baricitinib
T1
T1 — RCT in LC/PASC/PACVS
WithdrawnLong COVID
25 sources
  • T1WITHDRAWN NCT05858515 ↗REVERSE-Long COVID-19 With Baricitinib Study
  • T6INDIRECT 34911695 ↗The impact of therapeutics on mortality in hospitalised patients with COVID-19: systematic review an
  • T6INDIRECT 32454187 ↗Review of trials currently testing treatment and prevention of COVID-19
  • T6INDIRECT 36385229 ↗Systemic corticosteroids for the treatment of COVID-19: Equity-related analyses and update on eviden
  • T6INDIRECT 34658014 ↗Colchicine for the treatment of COVID-19
  • T6INDIRECT 35316551 ↗A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendat
  • T6INDIRECT 34082281 ↗Digital imaging, technologies and artificial intelligence applications during COVID-19 pandemic
  • T6INDIRECT 34467402 ↗Fostamatinib for the Treatment of Hospitalized Adults With Coronavirus Disease 2019: A Randomized Tr
  • T1 33962573 ↗Impact of high dose of baricitinib in severe COVID-19 pneumonia: a prospective cohort study in Bangl
  • T6 35271343 ↗The immunology and immunopathology of COVID-19
  • T6 33743212 ↗COVID-19 and the human innate immune system
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 36253560 ↗Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential t
  • T6INDIRECT 33856918 ↗COVID-19 and Cardiovascular Disease: From Bench to Bedside
  • T6INDIRECT 33529600 ↗Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning
  • T6INDIRECT 34944099 ↗New Onset of Autoimmune Diseases Following COVID-19 Diagnosis
  • T6INDIRECT 32584441 ↗Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the
  • T6INDIRECT 36100326 ↗Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue s
  • T6INDIRECT 36182669 ↗SARS-CoV-2 in immunocompromised individuals
  • T6INDIRECT 35912863 ↗Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches
  • T6INDIRECT 33586189 ↗COVID-19: immunopathology, pathophysiological mechanisms, and treatment options
  • T6 35931818 ↗Understanding COVID-19-associated coagulopathy
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 36631691 ↗Innate immune evasion strategies of SARS-CoV-2
cognitive rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
26 sources
  • T1 NCT05731570 ↗Cognitive Rehabilitation for People With Cognitive Covid19
  • T6 NCT07184398 ↗Use of a Cysteine-rich Whey Protein Isolate in Post COVID-19 Cognitive Impairment
  • T6INDIRECT 36657196 ↗Attention and memory after COVID-19 as measured by neuropsychological tests: Systematic review and m
  • T6INDIRECT 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T1 35537236 ↗COVID-19 associated cognitive impairment: A systematic review
  • T6INDIRECT 33637294 ↗Rehabilitation to enable recovery from COVID-19: a rapid systematic review
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 33584506 ↗COVID-19 Pathophysiology Predicts That Ischemic Stroke Occurrence Is an Expectation, Not an Exceptio
  • T6INDIRECT 36642173 ↗A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19
  • T1 38850628 ↗Neurocognitive Impairment in Long COVID: A Systematic Review
  • T6INDIRECT 36334288 ↗Recognizing the psychological impact of a glioma diagnosis on mental and behavioral health: a system
  • T6INDIRECT 37193738 ↗Effectiveness of a telerehabilitation intervention using ReCOVery APP of long COVID patients: a rand
  • T6 34818601 ↗The impact of the prolonged COVID-19 pandemic on stress resilience and mental health: A critical rev
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6INDIRECT 32990925 ↗Multiple Neuroinvasive Pathways in COVID-19
  • T4 34173049 ↗Cognitive decline following acute viral infections: literature review and projections for post-COVID
  • T6INDIRECT 35636906 ↗Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
  • T6INDIRECT 32475821 ↗The Stanford Hall consensus statement for post-COVID-19 rehabilitation
  • T6 37457901 ↗Post-COVID cognitive dysfunction: current status and research recommendations for high risk populati
  • T6 37795206 ↗Understanding Post-Sepsis Syndrome: How Can Clinicians Help?
  • T6 38094503 ↗Peripheral inflammation and neurocognitive impairment: correlations, underlying mechanisms, and ther
  • T6 35414261 ↗Brain Fog in Hypothyroidism: What Is It, How Is It Measured, and What Can Be Done About It
  • T6 37056914 ↗COVID-19 delirium and encephalopathy: Pathophysiology assumed in the first 3 years of the ongoing pa
  • T6 36103031 ↗Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19
  • T6 33789937 ↗Slow but Evident Recovery from Neocortical Dysfunction and Cognitive Impairment in a Series of Chron
  • T6 34764200 ↗Post-COVID-19 assessment in a specialist clinical service: a 12-month, single-centre, prospective st
concurrent training
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
25 sources
  • T1 NCT05204511 ↗Exercise and Post-COVID/ Long-COVID: Effects of Different Training Modalities on Various Parameters
  • T6INDIRECT 40122540 ↗Effectiveness and tolerance of exercise interventions for long COVID: a systematic review of randomi
  • T6INDIRECT 40115437 ↗Exercise-induced adaptations in the kynurenine pathway: implications for health and disease manageme
  • T6INDIRECT 38890699 ↗Effectiveness of pulmonary rehabilitation programmes and/or respiratory muscle training in patients
  • T6INDIRECT 39260851 ↗Clinical practice guidelines and expert consensus statements on rehabilitation for patients with COV
  • T6INDIRECT 36111386 ↗Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: A randomized
  • T1 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 39665835 ↗Exercise rehabilitation in post COVID-19 patients: a randomized controlled trial of different traini
  • T6INDIRECT 38102536 ↗Effect of different types of supervised exercise programs on cardiorespiratory and muscular fitness,
  • T6INDIRECT 38937986 ↗Telerehabilitation improves cardiorespiratory and muscular fitness and body composition in older peo
  • T6INDIRECT 36901146 ↗Effects of a Multi-Professional Intervention on Mental Health of Middle-Aged Overweight Survivors of
  • T6 33001410 ↗Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss
  • T6 34067776 ↗Post-COVID-19 Syndrome and the Potential Benefits of Exercise
  • T6INDIRECT 36560801 ↗Efficacy of Therapeutic Exercise in Reversing Decreased Strength, Impaired Respiratory Function, Dec
  • T6INDIRECT 37841213 ↗Complementary and alternative medicine for long COVID: a systematic review of randomized controlled
  • T6INDIRECT 41003635 ↗Post-Acute COVID-19 Syndrome (PACS) and Exercise Interventions: A Systematic Review of Randomized Co
  • T6INDIRECT 38711990 ↗Management of cognitive impairment associated with post-COVID-19 syndrome: recommendations for prima
  • T6INDIRECT 40805931 ↗Physical Training Protocols for Improving Dyspnea and Fatigue in Long COVID: A Systematic Review wit
  • T6INDIRECT 41741003 ↗Assessment and management of post-COVID-19 pulmonary complications: a rapid review
  • T6INDIRECT 42188575 ↗Strength and Conditioning Society (SCS) 8th Annual Meeting, Oslo, Norway, 2025
  • T6INDIRECT 39411230 ↗Recent highlights from the <i>International Journal of Cardiology Heart and Vasculature</i>: Spatiot
  • T6 38063644 ↗Effects of Different Protocols of Moderate-Intensity Intermittent Hypoxic Training on Mental Health
  • T6 36107382 ↗Abstracts of the XL Congress of the Spanish Society of Physiological Sciences (SECF)
  • T6 34861297 ↗Physical activity and COVID-19. The basis for an efficient intervention in times of COVID-19 pandemi
  • T6 37987274 ↗Long COVID and Physical Therapy: A Systematic Review
endurance training
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
26 sources
  • T1 NCT05204511 ↗Exercise and Post-COVID/ Long-COVID: Effects of Different Training Modalities on Various Parameters
  • T6INDIRECT 37725376 ↗Rehabilitation Interventions for Physical Capacity and Quality of Life in Adults With Post-COVID-19
  • T6INDIRECT 35908659 ↗Effect of Pulmonary Rehabilitation Approaches on Dyspnea, Exercise Capacity, Fatigue, Lung Functions
  • T6INDIRECT 34192010 ↗Changes in physical activity and sedentary behaviours from before to during the COVID-19 pandemic lo
  • T6INDIRECT 35265644 ↗Effect of Pulmonary Rehabilitation for Patients With Post-COVID-19: A Systematic Review and Meta-Ana
  • T6INDIRECT 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6INDIRECT 36334288 ↗Recognizing the psychological impact of a glioma diagnosis on mental and behavioral health: a system
  • T6INDIRECT 36717302 ↗Effects of physical rehabilitation interventions in COVID-19 patients following discharge from hospi
  • T6INDIRECT 36111386 ↗Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: A randomized
  • T6INDIRECT 37271020 ↗Effectiveness of exercise training on the dyspnoea of individuals with long COVID: A randomised cont
  • T6INDIRECT 36815161 ↗Inpatient post-COVID-19 rehabilitation program featuring virtual reality-Preliminary results of rand
  • T6 33001410 ↗Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss
  • T6 34067776 ↗Post-COVID-19 Syndrome and the Potential Benefits of Exercise
  • T6INDIRECT 35108624 ↗Respiratory rehabilitation in patients recovering from severe acute respiratory syndrome: A systemat
  • T6INDIRECT 33303102 ↗Screening of Potential Cardiac Involvement in Competitive Athletes Recovering From COVID-19: An Expe
  • T6INDIRECT 32483768 ↗Returning to Play after Prolonged Training Restrictions in Professional Collision Sports
  • T6INDIRECT 33801080 ↗Exercise Training and Cardiac Rehabilitation in COVID-19 Patients with Cardiovascular Complications:
  • T6INDIRECT 36615087 ↗Post-Acute Sequelae of COVID-19: The Potential Role of Exercise Therapy in Treating Patients and Ath
  • T6INDIRECT 34095290 ↗Benefits of pulmonary rehabilitation in COVID-19: a prospective observational cohort study
  • T6INDIRECT 34240576 ↗Providing rehabilitation to patients recovering from COVID-19: A scoping review
  • T6 37107158 ↗The Key Role of Mitochondrial Function in Health and Disease
  • T6 35336728 ↗Role of Epicardial Adipose Tissue in Cardiovascular Diseases: A Review
  • T6 36551869 ↗Understanding Long COVID; Mitochondrial Health and Adaptation-Old Pathways, New Problems
  • T6 38339220 ↗Role of microRNAs in Immune Regulation with Translational and Clinical Applications
  • T6 39679477 ↗Immune aging and infectious diseases
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
fluvoxamine
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
27 sources
  • T1 NCT05874037 ↗Fluvoxamine for Long COVID-19
  • T1 NCT06128967 ↗A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With L
  • T6INDIRECT 35726131 ↗Ivermectin for preventing and treating COVID-19
  • T6INDIRECT 38105461 ↗Outpatient randomized controlled trials to reduce COVID-19 hospitalization: Systematic review and me
  • T6INDIRECT 36399837 ↗Psychotropic drug repurposing for COVID-19: A Systematic Review and Meta-Analysis
  • T6INDIRECT 34318930 ↗Ivermectin for preventing and treating COVID-19
  • T6INDIRECT 36062970 ↗Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction
  • T1 33180097 ↗Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Random
  • T1 36070710 ↗Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19
  • T6INDIRECT 37302406 ↗Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT)
  • T6INDIRECT 38690892 ↗Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled
  • T6INDIRECT 35144974 ↗Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blin
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 36253560 ↗Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential t
  • T6INDIRECT 36271144 ↗Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications
  • T6INDIRECT 35727534 ↗Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 33421734 ↗The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacol
  • T6INDIRECT 32925078 ↗COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications
  • T6INDIRECT 35985357 ↗Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and re
  • T6INDIRECT 37445634 ↗Laboratory Findings and Biomarkers in Long COVID: What Do We Know So Far? Insights into Epidemiology
  • T6INDIRECT 34893494 ↗Learning through a Pandemic: The Current State of Knowledge on COVID-19 and Cancer
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 35672482 ↗Host-directed immunotherapy of viral and bacterial infections: past, present and future
  • T6 36776881 ↗The development of COVID-19 treatment
  • T6 36631691 ↗Innate immune evasion strategies of SARS-CoV-2
hyperbaric oxygen therapy (HBOT)
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFS
33 sources
  • T1REGISTERED-ONLY NCT06452095 ↗Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbar
  • T2REGISTERED-ONLY NCT07621068 ↗Hyperbaric Oxygen Therapy for Chronic Fatigue Syndrome (CFS)
  • T6INDIRECT 36032234 ↗Post-COVID-19 fatigue: A systematic review
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 34752489 ↗A mixed-methods systematic review of post-viral fatigue interventions: Are there lessons for long Co
  • T6INDIRECT 37344767 ↗Clinical effectiveness of rehabilitation in ambulatory care for patients with persisting symptoms af
  • T6INDIRECT 38673384 ↗Pathophysiological Mechanisms in Long COVID: A Mixed Method Systematic Review
  • T1 35821512 ↗Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: ra
  • T1 36208548 ↗Effects of hyperbaric oxygen therapy on functional and structural connectivity in post-COVID-19 cond
  • T1 36670365 ↗Hyperbaric oxygen therapy for long COVID (HOT-LoCO), an interim safety report from a randomised cont
  • T1 38360929 ↗Long term outcomes of hyperbaric oxygen therapy in post covid condition: longitudinal follow-up of a
  • T6 34163217 ↗The Conundrum of 'Long-COVID-19': A Narrative Review
  • T6 38374451 ↗Diabetes and infection: review of the epidemiology, mechanisms and principles of treatment
  • T2 36690401 ↗Efficacy and safety of hyperbaric oxygen therapy for fibromyalgia: a systematic review and meta-anal
  • T2 26010952 ↗Hyperbaric oxygen therapy can diminish fibromyalgia syndrome--prospective clinical trial
  • T6 24752591 ↗The glutathione system: a new drug target in neuroimmune disorders
  • T6 39548502 ↗Nanotechnology in healthcare, and its safety and environmental risks
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6INDIRECT 34215639 ↗Avascular necrosis as a part of 'long COVID-19'
  • T6INDIRECT 35373533 ↗International consensus statement on allergy and rhinology: Olfaction
  • T6INDIRECT 36299969 ↗Sudden Sensorineural Hearing Loss: A Review
  • T6 38534355 ↗Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders
  • T6 36043493 ↗The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid
  • T6 38998660 ↗<i>Aloe vera</i>-An Extensive Review Focused on Recent Studies
  • T6 34395187 ↗COVID-19 associated mucormycosis: Staging and management recommendations (Report of a multi-discipli
  • T6 37759498 ↗A Molecular Troika of Angiogenesis, Coagulopathy and Endothelial Dysfunction in the Pathology of Ava
  • T6 36283919 ↗Long COVID: An inevitable sequela of SARS-CoV-2 infection
  • T6INDIRECT 30210433 ↗Delayed Post-hypoxic Leukoencephalopathy (DPHL)-An Uncommon Variant of Hypoxic Brain Damage in Adult
  • T6INDIRECT 32161563 ↗Identification and Management of Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury
  • T6INDIRECT 36246401 ↗Oxidative Stress in Fibromyalgia: From Pathology to Treatment
  • T6INDIRECT 24115194 ↗Cutaneous manifestations of ESRD
  • T6 33114203 ↗Fibromyalgia: Recent Advances in Diagnosis, Classification, Pharmacotherapy and Alternative Remedies
intensive combined rehabilitation therapy
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05534997 ↗Rehabilitation Therapy for Post COVID 19 Chronic Fatigue Syndrome
ivabradine
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDPOTS
48 sources
  • T1 NCT06305806 ↗RECOVER-AUTONOMIC: Platform Protocol, Appendix B (Ivabradine)
  • T1 NCT06305780 ↗RECOVER-AUTONOMIC Platform Protocol
  • T2REGISTERED-ONLY NCT04186286 ↗Crossover Study of Propranolol vs Ivabradine in POTS
  • T2 NCT05481177 ↗Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
  • T2 NCT03182725 ↗Effect of Ivabradine on Patients With Postural Orthostatic Tachycardia Syndrome
  • T6 NCT01761825 ↗The Effect of Ivabradine on Patients With Postural Tachycardia Syndrome
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 38673384 ↗Pathophysiological Mechanisms in Long COVID: A Mixed Method Systematic Review
  • T6INDIRECT 36237182 ↗Graves' disease following vaccination against SARS-CoV-2: A systematic review of the reported cases
  • T6INDIRECT 37094584 ↗Postural Orthostatic Tachycardia Syndrome After COVID-19: A Systematic Review of Therapeutic Interve
  • T6INDIRECT 39882369 ↗Oral medications for the treatment of postural orthostatic tachycardia syndrome; a systematic review
  • T6INDIRECT 39538129 ↗Postural orthostatic tachycardia syndrome after COVID-19 vaccination: A systematic review
  • T6INDIRECT 36549786 ↗Effect of a home-based inspiratory muscle training programme on functional capacity in postdischarge
  • T6INDIRECT 39859026 ↗The Role of Omega-3 Polyunsaturated Fatty Acids in Patients with Metabolic Syndrome and Endothelial
  • T6INDIRECT 33786700 ↗Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infect
  • T6 32201335 ↗Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID
  • T6 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6 35176758 ↗Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
  • T6INDIRECT 29759520 ↗Ablation of Inappropriate Sinus Tachycardia: A Systematic Review of the Literature
  • T2 29330767 ↗Ivabradine for the Treatment of Postural Orthostatic Tachycardia Syndrome: A Systematic Review
  • T6INDIRECT 36723919 ↗Effect of Personalized Accelerated Pacing on Quality of Life, Physical Activity, and Atrial Fibrilla
  • T2 33602468 ↗Randomized Trial of Ivabradine in Patients With Hyperadrenergic Postural Orthostatic Tachycardia Syn
  • T6INDIRECT 37999672 ↗Noninvasive Vagus Nerve Stimulation in Postural Tachycardia Syndrome: A Randomized Clinical Trial
  • T6INDIRECT 37598401 ↗Semi-supervised exercise training program more effective for individuals with postural orthostatic t
  • T6INDIRECT 29217664 ↗Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Re
  • T6INDIRECT 31841279 ↗Central blood pressure for the management of hypertension: Is it a practical clinical tool in curren
  • T6INDIRECT 33723532 ↗Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrom
  • T6INDIRECT 33262898 ↗New-onset Postural Orthostatic Tachycardia Syndrome Following Coronavirus Disease 2019 Infection
  • T6INDIRECT 34821709 ↗Post-Acute Sequelae of COVID-19 and Cardiovascular Autonomic Dysfunction: What Do We Know?
  • T6INDIRECT 35853576 ↗Postural orthostatic tachycardia syndrome as a sequela of COVID-19
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 39125722 ↗Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detectio
  • T6 34403043 ↗Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor's pag
  • T6 34909198 ↗How COVID-19 can cause autonomic dysfunctions and postural orthostatic syndrome? A Review of mechani
  • T6 36113768 ↗Three-dimensional functional anatomy of the human sinoatrial node for epicardial and endocardial map
  • T6 39536116 ↗Translating insights into therapies for Long Covid
  • T6 34390682 ↗Post-COVID-19 Tachycardia Syndrome: A Distinct Phenotype of Post-Acute COVID-19 Syndrome
  • T6 35307156 ↗2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocard
  • T6INDIRECT 32117030 ↗Posterior Reversible Encephalopathy Syndrome: Clinical Features and Outcome
  • T6INDIRECT 26198889 ↗Postural Tachycardia Syndrome: Beyond Orthostatic Intolerance
  • T6INDIRECT 25980576 ↗2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tach
  • T6 29359025 ↗Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment
  • T6 34134525 ↗Recognition, Prevention, and Management of Arrhythmias and Autonomic Disorders in Cardio-Oncology: A
  • T6 33999297 ↗The autonomic nervous system in septic shock and its role as a future therapeutic target: a narrativ
  • T6 28428055 ↗Sex differences in cardiovascular disease - Impact on care and outcomes
  • T6 29222399 ↗Pediatric Disorders of Orthostatic Intolerance
lumbrokinase
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
11 sources
  • T1REGISTERED-ONLY NCT06511050 ↗Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalo
  • T6 36043493 ↗The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid
  • T6 41366804 ↗Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): diagnosis and management
  • T6 40721817 ↗Perioperative and anesthetic considerations for post-acute sequelae of COVID (PASC)/long COVID
  • T6 39762640 ↗Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series
  • T6 40627388 ↗Patient-reported treatment outcomes in ME/CFS and long COVID
  • T6INDIRECT 40709992 ↗Vaxtherapy, a Multiphase Therapeutic Protocol Approach for Longvax, the COVID-19 Vaccine-Induced Dis
  • T4 PPR728215 ↗Impact of extended-course oral nirmatrelvir/ritonavir (Paxlovid) in established Long COVID: Case ser
  • T6 40274794 ↗A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus
  • T6 41405757 ↗Investigation of the synergistic effect of enzymatic and Ultrasound-Induced amyloid microclot degrad
  • T6 42274123 ↗Dynamic microclot profiling: thromboelastography advances precision management in long COVID and mya
magnesium
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
27 sources
  • T1 NCT05630339 ↗Magnesium and Vitamin D Combination for Post-COVID Syndrome
  • T6 26404370 ↗Magnesium in Prevention and Therapy.
  • T6 25861976 ↗Ion channels in innate and adaptive immunity.
  • T6INDIRECT 34791425 ↗The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the mus
  • T6INDIRECT 35331487 ↗Clinical significance of micronutrient supplements in patients with coronavirus disease 2019: A comp
  • T6INDIRECT 35660931 ↗Global reports of myocarditis following COVID-19 vaccination: A systematic review and meta-analysis
  • T6INDIRECT 34396514 ↗Systemic corticosteroids for the treatment of COVID-19
  • T6INDIRECT 34679203 ↗Antibiotics for the treatment of COVID-19
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 36385229 ↗Systemic corticosteroids for the treatment of COVID-19: Equity-related analyses and update on eviden
  • T6INDIRECT 34658014 ↗Colchicine for the treatment of COVID-19
  • T6INDIRECT 37397709 ↗A systematic review of self-medication practice during the COVID-19 pandemic: implications for pharm
  • T6INDIRECT 37344767 ↗Clinical effectiveness of rehabilitation in ambulatory care for patients with persisting symptoms af
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 35727534 ↗Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment
  • T6INDIRECT 33425823 ↗Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculi
  • T6INDIRECT 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6INDIRECT 36364899 ↗A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
  • T6INDIRECT 36100326 ↗Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue s
  • T6 39174535 ↗Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strateg
  • T6 37402746 ↗TRP (transient receptor potential) ion channel family: structures, biological functions and therapeu
  • T6 3070321 ↗Linkage map of Salmonella typhimurium, edition VII
  • T6 33807579 ↗Allergic Reactions to Current Available COVID-19 Vaccinations: Pathophysiology, Causality, and Thera
  • T6 34715347 ↗Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
melatonin
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVIDME/CFSPOTS
81 sources
  • T1 NCT06404112 ↗RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
  • T1 NCT06404086 ↗RECOVER-SLEEP: Platform Protocol
  • T2 NCT05454683 ↗Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue
  • T2 NCT03000777 ↗Oral Melatonin Plus Zinc Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/
  • T2REGISTERED-ONLY NCT00262470 ↗Treatment of Orthostatic Intolerance
  • T6INDIRECT 36235869 ↗Vitamin C Supplementation for the Treatment of COVID-19: A Systematic Review and Meta-Analysis
  • T6INDIRECT 38732592 ↗The Efficacy of Multivitamin, Vitamin A, Vitamin B, Vitamin C, and Vitamin D Supplements in the Prev
  • T6INDIRECT 38105461 ↗Outpatient randomized controlled trials to reduce COVID-19 hospitalization: Systematic review and me
  • T6INDIRECT 33205450 ↗Case report and systematic review suggest that children may experience similar long-term effects to
  • T6INDIRECT 33584506 ↗COVID-19 Pathophysiology Predicts That Ischemic Stroke Occurrence Is an Expectation, Not an Exceptio
  • T6INDIRECT 35893864 ↗The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musc
  • T6INDIRECT 37397709 ↗A systematic review of self-medication practice during the COVID-19 pandemic: implications for pharm
  • T6INDIRECT 36334288 ↗Recognizing the psychological impact of a glioma diagnosis on mental and behavioral health: a system
  • T6INDIRECT 34837648 ↗Comparing efficacy and safety of different doses of dexamethasone in the treatment of COVID-19: a th
  • T6INDIRECT 38908733 ↗Fecal Microbiota Transplantation for Sleep Disturbance in Post-acute COVID-19 Syndrome
  • T6 39174535 ↗Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strateg
  • T6 37117704 ↗Wearable chemical sensors for biomarker discovery in the omics era
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metformin
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
29 sources
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  • T1 NCT06128967 ↗A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With L
  • T6 NCT07280572 ↗RECLAIM Adaptive Platform Trial for PCC Treatments
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  • T6INDIRECT 34318930 ↗Ivermectin for preventing and treating COVID-19
  • T6INDIRECT 34679203 ↗Antibiotics for the treatment of COVID-19
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  • T6INDIRECT 37302406 ↗Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT)
  • T6INDIRECT 34837648 ↗Comparing efficacy and safety of different doses of dexamethasone in the treatment of COVID-19: a th
  • T1 38690892 ↗Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled
  • T6INDIRECT 36429613 ↗Pulmonary and Functional Rehabilitation Improves Functional Capacity, Pulmonary Function and Respira
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  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 33529600 ↗Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning
  • T6INDIRECT 36364899 ↗A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
  • T6INDIRECT 36464706 ↗Small molecules in the treatment of COVID-19
  • T6INDIRECT 32651031 ↗COVID-19 in people living with diabetes: An international consensus
  • T6INDIRECT 37298527 ↗Neurodegenerative and Neurodevelopmental Diseases and the Gut-Brain Axis: The Potential of Therapeut
  • T6 36050306 ↗Lactate metabolism in human health and disease
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 37130947 ↗Metformin: update on mechanisms of action and repurposing potential
  • T6 34127835 ↗Hypertension-induced cognitive impairment: from pathophysiology to public health
  • T6 36253560 ↗Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential t
  • T6 35668219 ↗The burden and risks of emerging complications of diabetes mellitus
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microcrystalline cellulose
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
25 sources
  • T1 NCT06348212 ↗Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
  • T6INDIRECT 34658014 ↗Colchicine for the treatment of COVID-19
  • T6INDIRECT 36103313 ↗Fluvoxamine for the treatment of COVID-19
  • T6INDIRECT 35144974 ↗Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blin
  • T6INDIRECT 39356507 ↗Lithium Aspartate for Long COVID Fatigue and Cognitive Dysfunction: A Randomized Clinical Trial
  • T6INDIRECT 37739466 ↗Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: a double-blin
  • T6INDIRECT 40439228 ↗Efficacy of bismuth subsalicylate on the prevention of travellers' diarrhoea, 2018-2023
  • T6INDIRECT 37891178 ↗Standardized Brazilian green propolis extract (EPP-AF®) in COVID-19 outcomes: a randomized double-bl
  • T6 27287427 ↗Cellulases and beyond: the first 70 years of the enzyme producer Trichoderma reesei
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
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  • T6INDIRECT 34991703 ↗Double-blind placebo-controlled randomized clinical trial to assess the efficacy of montelukast in m
  • T6INDIRECT 36015163 ↗Efficacy of Kan Jang<sup>®</sup> in Patients with Mild COVID-19: Interim Analysis of a Randomized, Q
  • T6INDIRECT 35241474 ↗Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: study protoco
  • T6INDIRECT 40692561 ↗Comparative cohort study of post-acute COVID-19 infection with a nested, randomized controlled trial
  • T6INDIRECT 40280611 ↗Ashwagandha (&lt;i&gt;Withania somnifera (L.) Dunal&lt;/i&gt;) for promoting recovery in long covid:
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  • T6 29155571 ↗Oxygen Activation by Cu LPMOs in Recalcitrant Carbohydrate Polysaccharide Conversion to Monomer Suga
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  • T6 23124232 ↗Cello-oligosaccharide oxidation reveals differences between two lytic polysaccharide monooxygenases
  • T6 20359453 ↗Thermostable enzymes as biocatalysts in the biofuel industry
  • T6 29472725 ↗An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and bio
mindfulness-based stress reduction and cognitive behavioral therapy
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
4 sources
  • T1 NCT05815693 ↗Cognitive-behavioral Therapy for Mental Disorder in COVID-19 Survivors
  • T6INDIRECT 41736971 ↗Resilience under pressure: a systematic review of psychological coping and endurance mechanisms amon
  • T6 35195724 ↗Association of Chiropractic Colleges Research Agenda Conference 2022: Wellness and Health Promotion:
  • T6 PMC11706432 ↗ARE HUMANS MUSICAL BEINGS? RELATIONSHIPS BETWEEN MUSIC, RHYTHM AND PSYCHOLOGICAL WELL-BEING
multi-domain Tai Chi Digital therapy Software Application
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
naltrexone (LDN)
T1
T1 — RCT in LC/PASC/PACVS
RegisteredWithdrawnLong COVIDME/CFSPOTS
65 sources
  • T1REGISTERED-ONLY NCT06366724 ↗LIFT: Life Improvement Trial
  • T2REGISTERED-ONLY NCT07285473 ↗Low-Dose Naltrexone For ME/CFS: Dose-Finding
  • T2WITHDRAWN NCT02965768 ↗Immune Effects of Low-dose Naltrexone in ME/CFS
  • T2REGISTERED-ONLY NCT05363514 ↗Low Dose Naltrexone Use in Patients With POTS
  • T6INDIRECT 39483457 ↗Meta-analysis of natural killer cell cytotoxicity in myalgic encephalomyelitis/chronic fatigue syndr
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 34658014 ↗Colchicine for the treatment of COVID-19
  • T6INDIRECT 36409650 ↗A systematic review of the biological mediators of fat taste and smell
  • T6INDIRECT 39940333 ↗Dietary Supplementation for Fatigue Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (
  • T6INDIRECT 38554565 ↗Examining inequities in access to opioid agonist treatment (OAT) take-home doses (THD): A Canadian O
  • T6INDIRECT 38360929 ↗Long term outcomes of hyperbaric oxygen therapy in post covid condition: longitudinal follow-up of a
  • T6INDIRECT 36196533 ↗Enhancing Use of Medications for Opioid Use Disorder Through External Coaching
  • T6INDIRECT 38012333 ↗A practice quit model to test early efficacy of medications for alcohol use disorder in a randomized
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T2HARM 30642329 ↗Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a system
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  • T6INDIRECT 27894343 ↗Post-marketing withdrawal of anti-obesity medicinal products because of adverse drug reactions: a sy
  • T6INDIRECT 34352116 ↗Primary-level worker interventions for the care of people living with mental disorders and distress
  • T6INDIRECT 34601272 ↗Opioid-induced analgesia among persons with opioid use disorder receiving methadone or buprenorphine
  • T6INDIRECT 25879513 ↗Excessive Sugar Consumption May Be a Difficult Habit to Break: A View From the Brain and Body
  • T6INDIRECT 34014691 ↗Applying methods for personalized medicine to the treatment of alcohol use disorder
  • T2 19453963 ↗Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study
  • T6INDIRECT 15834216 ↗Dissection of hypothalamic-pituitary-adrenal axis pathology in 1-month-abstinent alcohol-dependent m
  • T2 31736966 ↗Naltrexone Restores Impaired Transient Receptor Potential Melastatin 3 Ion Channel Function in Natur
  • T6 2683611 ↗Biology of natural killer cells
  • T6INDIRECT 33687070 ↗Smoking cessation for improving mental health
  • T6INDIRECT 37189381 ↗Dupilumab in Inflammatory Skin Diseases: A Systematic Review
  • T6INDIRECT 31702122 ↗Autonomic dysfunction and sudden death in patients with Rett syndrome: a systematic review
  • T6INDIRECT 39882369 ↗Oral medications for the treatment of postural orthostatic tachycardia syndrome; a systematic review
  • T6INDIRECT 39042627 ↗Six-year follow-up of participants in two clinical trials of rituximab or cyclophosphamide in Myalgi
  • T6 34942142 ↗The neuropsychiatry of Parkinson's disease: advances and challenges
  • T6 34067776 ↗Post-COVID-19 Syndrome and the Potential Benefits of Exercise
  • T6 35172971 ↗Risks of mental health outcomes in people with covid-19: cohort study
  • T6INDIRECT 28922704 ↗Direct-acting antivirals for chronic hepatitis C
  • T6INDIRECT 23450540 ↗Methadone at tapered doses for the management of opioid withdrawal
  • T6INDIRECT 20680369 ↗A systematic review on the effectiveness of pharmacological interventions for chronic non-specific l
  • T6INDIRECT 35234292 ↗Pharmacotherapy for post traumatic stress disorder (PTSD)
  • T6INDIRECT 18161012 ↗Effects of THC and lofexidine in a human laboratory model of marijuana withdrawal and relapse
  • T6INDIRECT 25827659 ↗A pilot trial of prazosin, an alpha-1 adrenergic antagonist, for comorbid alcohol dependence and pos
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 36100326 ↗Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue s
  • T6INDIRECT 36464706 ↗Small molecules in the treatment of COVID-19
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6 36899952 ↗Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome and Potential Therapeutic
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 33240091 ↗Challenges for Drug Repurposing in the COVID-19 Pandemic Era
  • T5 31911410 ↗Low-dose naltrexone as a treatment for chronic fatigue syndrome
  • T6INDIRECT 37445634 ↗Laboratory Findings and Biomarkers in Long COVID: What Do We Know So Far? Insights into Epidemiology
  • T6INDIRECT 36169154 ↗Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of aut
  • T6 29462012 ↗Neuroinflammation and Central Sensitization in Chronic and Widespread Pain
  • T6 29867317 ↗Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder
  • T6 37069462 ↗Microglia polarization in nociplastic pain: mechanisms and perspectives
  • T6 30146050 ↗Pain Modulation: From Conditioned Pain Modulation to Placebo and Nocebo Effects in Experimental and
  • T6 33062901 ↗Exercise-induced hypoalgesia after acute and regular exercise: experimental and clinical manifestati
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  • T6INDIRECT 25081580 ↗Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsess
  • T6INDIRECT 24433463 ↗Review of pharmacological therapies in fibromyalgia syndrome
  • T6 19345246 ↗Opioid receptors in the gastrointestinal tract
  • T6 31387301 ↗Mechanisms of Botulinum Toxin Type A Action on Pain
  • T6 29055040 ↗THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors
  • T6 30653247 ↗Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review
  • T6 30291106 ↗Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes As
  • T6 26650439 ↗The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors
nirmatrelvir/ritonavir (Paxlovid)
T1
T1 — RCT in LC/PASC/PACVS
Harm signalRegisteredLong COVID
29 sources
  • T1 NCT05576662 ↗Paxlovid for Treatment of Long Covid
  • T1HARM NCT05668091 ↗A Decentralized, Randomized Phase 2 Efficacy and Safety Study of Nirmatrelvir/Ritonavir in Adults wi
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  • T1 NCT05965726 ↗RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms
  • T1REGISTERED-ONLY NCT06792214 ↗Antiviral Strategies in the Prevention of Long-term Cardiovascular Outcomes Following COVID-19: The
  • T1 NCT05823896 ↗ImPROving Quality of LIFe in the Long COVID Patient
  • T6INDIRECT 38105461 ↗Outpatient randomized controlled trials to reduce COVID-19 hospitalization: Systematic review and me
  • T6INDIRECT 35878897 ↗Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis
  • T6INDIRECT 35955740 ↗COVID-19 and the Immune Response: A Multi-Phasic Approach to the Treatment of COVID-19
  • T6INDIRECT 38032024 ↗Nirmatrelvir combined with ritonavir for preventing and treating COVID-19
  • T6INDIRECT 38848477 ↗Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection: The S
  • T6INDIRECT 35995785 ↗Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults wit
  • T6INDIRECT 38690892 ↗Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled
  • T6INDIRECT 40188838 ↗Nirmatrelvir-ritonavir versus placebo-ritonavir in individuals with long COVID in the USA (PAX LC):
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  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 36947108 ↗Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)
  • T6INDIRECT 36933565 ↗Effectiveness of nirmatrelvir-ritonavir in preventing hospital admissions and deaths in people with
  • T6INDIRECT 36182669 ↗SARS-CoV-2 in immunocompromised individuals
  • T6INDIRECT 35912863 ↗Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches
  • T6INDIRECT 36464706 ↗Small molecules in the treatment of COVID-19
  • T6INDIRECT 36969241 ↗Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOV
  • T6INDIRECT 36407883 ↗Immunocompromised Patients with Protracted COVID-19: a Review of "Long Persisters"
  • T6INDIRECT 36851722 ↗Impact of COVID-19 on Cardiovascular Disease
  • T6INDIRECT 39256346 ↗Emerging and reemerging infectious diseases: global trends and new strategies for their prevention a
  • T6 36899952 ↗Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome and Potential Therapeutic
  • T6 37018987 ↗Paxlovid (Nirmatrelvir/Ritonavir): A new approach to Covid-19 therapy?
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
online visit
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
7 sources
  • T1REGISTERED-ONLY NCT07352254 ↗OutreAch MediCal Care for HousEbound Patients With Post-COVID-19 Syndrome or ME/CFS of Any Cause (AC
  • T6 37265696 ↗Telemedicine for diabetes management during COVID-19: what we have learnt, what and how to implement
  • T6 34574480 ↗Telemedicine and eHealth Literacy in the Era of COVID-19: A Cross-Sectional Study in a Peripheral Cl
  • T6 34205724 ↗Lessons Learned during a Naturalistic Study of Online Treatment for Pediatric Rehabilitation
  • T6 33994649 ↗Restarting "Normal" Life after Covid-19 and the Lockdown: Evidence from Spain, the United Kingdom, a
  • T6 33385246 ↗Implementing telemedicine for the management of benign urologic conditions: a single centre experien
  • T4 PMC8487351 ↗UEG Week 2021 Poster Presentations
pulmonary rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
28 sources
  • T1 NCT05244044 ↗Pulmonary Rehabilitation for Long COVID (Post COVID-19 Condition)
  • T1 NCT05379517 ↗Pulmonary Rehabilitation Program With Pulsed Electromagnetic Field Therapy in Patients With Post-cov
  • T1 36223120 ↗Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic R
  • T6INDIRECT 35182760 ↗ESCMID rapid guidelines for assessment and management of long COVID
  • T6INDIRECT 37725376 ↗Rehabilitation Interventions for Physical Capacity and Quality of Life in Adults With Post-COVID-19
  • T6INDIRECT 34592585 ↗Telehealth utilization during the Covid-19 pandemic: A systematic review
  • T6INDIRECT 35564579 ↗Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 35236727 ↗Inspiratory muscle training enhances recovery post-COVID-19: a randomised controlled trial
  • T6INDIRECT 36111386 ↗Rehabilitation for post-COVID-19 condition through a supervised exercise intervention: A randomized
  • T6INDIRECT 36476156 ↗Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations o
  • T6INDIRECT 34351016 ↗Incidence and risk factors for persistent symptoms in adults previously hospitalized for COVID-19
  • T6 33753937 ↗Post-acute COVID-19 syndrome
  • T6 34265229 ↗Symptoms, complications and management of long COVID: a review
  • T6INDIRECT 33146552 ↗Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease.
  • T6INDIRECT 33609255 ↗A Review of Persistent Post-COVID Syndrome (PPCS)
  • T6INDIRECT 34328636 ↗Post-COVID-19 acute sarcopenia: physiopathology and management
  • T6INDIRECT 32475821 ↗The Stanford Hall consensus statement for post-COVID-19 rehabilitation
  • T6 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6 33857435 ↗Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuro
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6 34451904 ↗Lung Fibrosis after COVID-19: Treatment Prospects
  • T6 33686978 ↗Post-COVID lung fibrosis: The tsunami that will follow the earthquake
  • T6 35566253 ↗The Pathophysiology of Long COVID throughout the Renin-Angiotensin System
  • T6 34401216 ↗Cellular Senescence in Idiopathic Pulmonary Fibrosis
  • T6 35472304 ↗Clinical characteristics with inflammation profiling of long COVID and association with 1-year recov
  • T6 35176758 ↗Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
  • T6 33964245 ↗3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related
pyridostigmine
T1
T1 — RCT in LC/PASC/PACVS
Harm signalRegisteredLong COVIDPOTS
57 sources
  • T1REGISTERED-ONLY NCT06366724 ↗LIFT: Life Improvement Trial
  • T2REGISTERED-ONLY NCT03124355 ↗Vagal Stimulation in POTS
  • T2 NCT03261570 ↗Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTS
  • T2HARM NCT03674541 ↗The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chroni
  • T6REGISTERED-ONLY NCT00409435 ↗A Study of Pyridostigmine in Postural Tachycardia Syndrome
  • T6INDIRECT 39882369 ↗Oral medications for the treatment of postural orthostatic tachycardia syndrome; a systematic review
  • T6INDIRECT 39538129 ↗Postural orthostatic tachycardia syndrome after COVID-19 vaccination: A systematic review
  • T6INDIRECT 40426137 ↗Inspiratory muscle training and aerobic exercise for respiratory muscle strength in myasthenia gravi
  • T6INDIRECT 33460984 ↗Impact of COVID-19 pandemic and lockdown in a cohort of myasthenia gravis patients in India
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6 34024217 ↗Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments
  • T6 33595463 ↗COVID-19 and Eye: A Review of Ophthalmic Manifestations of COVID-19
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6INDIRECT 33723532 ↗Long-Haul Post-COVID-19 Symptoms Presenting as a Variant of Postural Orthostatic Tachycardia Syndrom
  • T6INDIRECT 15911704 ↗Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome
  • T6INDIRECT 22677718 ↗A randomised controlled study of the effect of cholinesterase inhibition on colon function in patien
  • T6INDIRECT 23978222 ↗A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropath
  • T2 18240245 ↗A six-month randomized controlled trial of exercise and pyridostigmine in the treatment of fibromyal
  • T2 29500811 ↗Efficacy of Propranolol, Bisoprolol, and Pyridostigmine for Postural Tachycardia Syndrome: a Randomi
  • T6INDIRECT 19506222 ↗Efficacy of immunotherapy in seropositive and seronegative putative autoimmune autonomic ganglionopa
  • T6INDIRECT 26387781 ↗Effect of neostigmine on gastroduodenal motility in patients with suspected gastrointestinal motilit
  • T6INDIRECT 17016160 ↗Acetylcholinesterase inhibition in patients with orthostatic intolerance
  • T6INDIRECT 23116538 ↗Treatment of multiple system atrophy using intravenous immunoglobulin
  • T6HARM 29442540 ↗Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor The
  • T6INDIRECT 34752479 ↗Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled
  • T6INDIRECT 22591985 ↗Efficacy of treatments for orthostatic hypotension: a systematic review
  • T6INDIRECT 31214762 ↗Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review
  • T2 16476804 ↗Pyridostigmine treatment trial in neurogenic orthostatic hypotension
  • T2 20837887 ↗Comparative efficacy of yohimbine against pyridostigmine for the treatment of orthostatic hypotensio
  • T6INDIRECT 12933939 ↗Acetylcholinesterase inhibition: a novel approach in the treatment of neurogenic orthostatic hypoten
  • T6INDIRECT 33262898 ↗New-onset Postural Orthostatic Tachycardia Syndrome Following Coronavirus Disease 2019 Infection
  • T6INDIRECT 33047223 ↗New onset of ocular myasthenia gravis in a patient with COVID-19: a novel case report and literature
  • T6INDIRECT 34821709 ↗Post-Acute Sequelae of COVID-19 and Cardiovascular Autonomic Dysfunction: What Do We Know?
  • T6INDIRECT 34216297 ↗COVID-19 and Myositis: What We Know So Far
  • T6 33240091 ↗Challenges for Drug Repurposing in the COVID-19 Pandemic Era
  • T6 36174571 ↗Bioelectronic medicine: Preclinical insights and clinical advances
  • T6 38534355 ↗Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders
  • T6 38887284 ↗Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: the biology of a neglected disease
  • T6 37028776 ↗Neuroimmune nexus in the pathophysiology and therapy of inflammatory disorders: Role of α7 nicotinic
  • T6 39444797 ↗Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long
  • T6 34390682 ↗Post-COVID-19 Tachycardia Syndrome: A Distinct Phenotype of Post-Acute COVID-19 Syndrome
  • T6INDIRECT 29508455 ↗Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies
  • T6INDIRECT 23186897 ↗Transverse myelitis
  • T6INDIRECT 19713422 ↗Guidelines for the diagnosis and management of syncope (version 2009)
  • T6INDIRECT 25980576 ↗2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tach
  • T6 26493934 ↗Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effe
  • T6 28303218 ↗The modification of natural products for medical use
  • T6 29717928 ↗Impact of the Autonomic Nervous System on the Skeleton
  • T6 30793549 ↗Update on the Impact, Diagnosis and Management of Cardiovascular Autonomic Neuropathy in Diabetes: W
  • T6 33924103 ↗Treatment Options for Motor and Non-Motor Symptoms of Parkinson's Disease
  • T6 29359025 ↗Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment
  • T6 21962754 ↗Multiple system atrophy: a clinical and neuropathological perspective
  • T6 34134525 ↗Recognition, Prevention, and Management of Arrhythmias and Autonomic Disorders in Cardio-Oncology: A
  • T6 20103559 ↗Cardiac autonomic neuropathy in diabetes: a clinical perspective
  • T6 28050656 ↗The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic o
  • T6 23122672 ↗Postural tachycardia syndrome: a heterogeneous and multifactorial disorder
  • T6 19207771 ↗Postural tachycardia syndrome (POTS)
qEEG-neurofeedback
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
19 sources
  • T1REGISTERED-ONLY NCT07005921 ↗Attention, Memory and Quality of Life in Post-COVID-19 Adults
  • T6INDIRECT 39206795 ↗Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and
  • T6INDIRECT 40365003 ↗Using physiological biomarkers in forensic psychiatry: a scoping review
  • T6 33809957 ↗Changes in EEG Recordings in COVID-19 Patients as a Basis for More Accurate QEEG Diagnostics and EEG
  • T6 36081063 ↗Comparison of QEEG Findings before and after Onset of Post-COVID-19 Brain Fog Symptoms
  • T6 35895740 ↗Effect of neurofeedback therapy on neurological post-COVID-19 complications (A pilot study)
  • T6 36277052 ↗Quantitative electroencephalography interpretation of human brain activity after COVID-19 before and
  • T6INDIRECT 38646408 ↗Efficacy of Original Neurofeedback Treatment Method for Brain Fog From COVID-19: A Case Report
  • T6INDIRECT 42121889 ↗Alterations in Cortical Oscillatory Dynamics Following SARS-CoV-2 Infection: QEEG Biomarkers of Vuln
  • T6INDIRECT 34857904 ↗ACNP 60<sup>th</sup> Annual Meeting: Poster Abstracts P1 - P275
  • T6INDIRECT 40115713 ↗Neurofeedback for COVID-19 Brain Fog: A Secondary Analysis
  • T6 36456693 ↗ACNP 61<sup>st</sup> Annual Meeting: Poster Abstracts P1 - P270
  • T6 33231810 ↗Abstracts of the 51st Annual Conference of the Italian Society of Neurology : November 28- 30, 2020
  • T6 PMC11932184 ↗FREE PAPERS
  • T6 PMC10729596 ↗ACNP 62nd Annual Meeting: Poster Abstracts P251 – P500
  • T6 PMC10729595 ↗ACNP 62nd Annual Meeting: Poster Abstracts P1 – P250
  • T6 PMC8637057 ↗ACNP 60th Annual Meeting: Keyword Index
  • T6 40150759 ↗Electroencephalographic Biomarkers for Neuropsychiatric Diseases: The State of the Art
  • T6 35431842 ↗Possible Mechanisms Underlying Neurological Post-COVID Symptoms and Neurofeedback as a Potential The
remdesivir
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
28 sources
  • T1REGISTERED-ONLY NCT06792214 ↗Antiviral Strategies in the Prevention of Long-term Cardiovascular Outcomes Following COVID-19: The
  • T6INDIRECT 33549624 ↗COVID-19 in immunocompromised patients: A systematic review of cancer, hematopoietic cell and solid
  • T6INDIRECT 33246166 ↗COVID-19 in solid organ transplant recipients: A systematic review and meta-analysis of current lite
  • T6INDIRECT 35057437 ↗Effectiveness of Curcumin on Outcomes of Hospitalized COVID-19 Patients: A Systematic Review of Clin
  • T6INDIRECT 34396514 ↗Systemic corticosteroids for the treatment of COVID-19
  • T6INDIRECT 34318930 ↗Ivermectin for preventing and treating COVID-19
  • T6INDIRECT 34452974 ↗Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalitis Following COVID-19: Sys
  • T6INDIRECT 34386902 ↗Association of CNS demyelination and COVID-19 infection: an updated systematic review
  • T6INDIRECT 33036570 ↗Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
  • T6INDIRECT 38848477 ↗Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection: The S
  • T6INDIRECT 37276589 ↗Effectiveness of COVID-19 Treatment With Nirmatrelvir-Ritonavir or Molnupiravir Among U.S. Veterans:
  • T6 32201335 ↗Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID
  • T6 35271343 ↗The immunology and immunopathology of COVID-19
  • T6INDIRECT 32653054 ↗Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally a
  • T6INDIRECT 34156034 ↗Epidemiology, clinical profile, management, and outcome of COVID-19-associated rhino-orbital-cerebra
  • T6INDIRECT 33146552 ↗Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease.
  • T6INDIRECT 33723416 ↗The first 12 months of COVID-19: a timeline of immunological insights
  • T6INDIRECT 33856918 ↗COVID-19 and Cardiovascular Disease: From Bench to Bedside
  • T6INDIRECT 32857878 ↗Thrombosis in COVID-19
  • T6INDIRECT 33529600 ↗Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning
  • T6 37076602 ↗Therapeutic strategies for COVID-19: progress and lessons learned
  • T6 33857435 ↗Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuro
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 33219837 ↗Severe COVID-19, multisystem inflammatory syndrome in children, and Kawasaki disease: immunological
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 35216673 ↗A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
  • T6 33892403 ↗Long COVID: An overview
  • T6 35176758 ↗Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
self- applied acupressure plus Qigong course plus advice literature
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05289154 ↗Acupressure and Qigong in Chronic Fatigue Post COVID-19.
stellate ganglion block
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
19 sources
  • T1 NCT05638620 ↗Dual Sympathetic Blocks for Patients Experiencing Sympathetically-Mediated Symptoms From Long COVID
  • T1 41973314 ↗Stellate Ganglion Block in the Treatment of Long COVID: A Systematic Review
  • T1 40504522 ↗Stellate Ganglion Block for the Treatment of COVID-19-Induced Parosmia: A Randomized Clinical Trial
  • T1 40739539 ↗A prospective randomized clinical trial on the differential effect of left versus right stellate gan
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6 35411324 ↗Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From t
  • T6 36949968 ↗A Review of Stellate Ganglion Block as an Adjunctive Treatment Modality
  • T5 34922127 ↗Stellate ganglion block reduces symptoms of Long COVID: A case series
  • T6 35614970 ↗The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Fail
  • T5 36106285 ↗Stellate Ganglion Block for Anosmia and Dysgeusia Due to Long COVID
  • T5 36628048 ↗Stellate Ganglion Block for Long COVID Symptom Management: A Case Report
  • T5 37496529 ↗Efficacy of Stellate Ganglion Block in Treating Long-Term COVID-19-Related Olfactory and Gustatory D
  • T6INDIRECT 36074973 ↗Sinus Tachycardia: a Multidisciplinary Expert Focused Review
  • T6INDIRECT 40046430 ↗Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechan
  • T6 37366867 ↗Post-COVID-19 Anosmia and Therapies: Stay Tuned for New Drugs to Sniff Out
  • T6 42325367 ↗Long COVID: current research and future directions
  • T6 37386671 ↗Abstracts of the ICARE 2022 76th SIAARTI National Congress : Milan, Italy. 28-30 October 2022
  • T6 35934749 ↗ESNR 2022
  • T6 PMC12502813 ↗Book of Posters
symptom-focused rehabilitation
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
1 source
  • T1 NCT05172206 ↗Symptom-based Rehabilitation Compared to Usual Care in Post-COVID - a Randomized Controlled Trial
tDCS-active
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
22 sources
  • T1 NCT05965739 ↗RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS I
  • T1 NCT05965752 ↗RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Lo
  • T6INDIRECT 39025832 ↗Evaluating the effects of tDCS on depressive and anxiety symptoms from a transdiagnostic perspective
  • T6INDIRECT 38329083 ↗Efficacy and safety of transcranial magnetic stimulation on cognition in mild cognitive impairment,
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 36834176 ↗Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review
  • T6INDIRECT 38214047 ↗Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation
  • T6INDIRECT 36693536 ↗Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC)
  • T6INDIRECT 38272997 ↗Transcranial direct current stimulation (tDCS) in the treatment of neuropsychiatric symptoms of long
  • T6 38378653 ↗Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatme
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 35734582 ↗Non-invasive brain stimulation and neuroenhancement
  • T6 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6 39232147 ↗Immune system adaptation during gender-affirming testosterone treatment
  • T6INDIRECT 38962179 ↗Current state of clinical ultrasound neuromodulation
  • T6INDIRECT 38495306 ↗Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19
  • T6INDIRECT 39536116 ↗Translating insights into therapies for Long Covid
  • T6INDIRECT 35911909 ↗Neuromodulation Strategies to Reduce Inflammation and Improve Lung Complications in COVID-19 Patient
  • T6INDIRECT 35410927 ↗Neuromodulation through brain stimulation-assisted cognitive training in patients with post-COVID-19
  • T6 36174571 ↗Bioelectronic medicine: Preclinical insights and clinical advances
  • T6 35712237 ↗Fish and the Thyroid: A Janus Bifrons Relationship Caused by Pollutants and the Omega-3 Polyunsatura
  • T6 33324324 ↗Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19
tenofovir disoproxil/emtricitabine
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
3 sources
  • T1REGISTERED-ONLY NCT06511063 ↗Antiviral Clinical Trial for Long Covid-19
  • T6 40559563 ↗Digestive Manifestations of Post-COVID-19: A Focus on Therapeutic Strategies
  • T6 36609708 ↗Sustaining PrEP Prescriptions at a Safety-Net Hospital in New York City During COVID-19: Lessons Lea
transcranial direct current stimulation (tDCS)
T1
T1 — RCT in LC/PASC/PACVS
RegisteredWithdrawnLong COVID
24 sources
  • T6INDIRECT 39025832 ↗Evaluating the effects of tDCS on depressive and anxiety symptoms from a transdiagnostic perspective
  • T1 38329083 ↗Efficacy and safety of transcranial magnetic stimulation on cognition in mild cognitive impairment,
  • T6INDIRECT 39603702 ↗Interventions for the management of long covid (post-covid condition): living systematic review
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 36834176 ↗Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review
  • T6INDIRECT 36642173 ↗A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19
  • T6INDIRECT 38214047 ↗Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation
  • T6INDIRECT 38695969 ↗Intervention modalities for brain fog caused by long-COVID: systematic review of the literature
  • T6INDIRECT 36693536 ↗Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC)
  • T1 38272997 ↗Transcranial direct current stimulation (tDCS) in the treatment of neuropsychiatric symptoms of long
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 35734582 ↗Non-invasive brain stimulation and neuroenhancement
  • T6INDIRECT 35727534 ↗Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment
  • T6INDIRECT 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6INDIRECT 34593760 ↗Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and therapeutic inter
  • T6INDIRECT 34403043 ↗Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor's pag
  • T6INDIRECT 38962179 ↗Current state of clinical ultrasound neuromodulation
  • T6INDIRECT 38495306 ↗Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19
  • T4 33281589 ↗Update on the Use of Transcranial Electrical Brain Stimulation to Manage Acute and Chronic COVID-19
  • T6 36174571 ↗Bioelectronic medicine: Preclinical insights and clinical advances
  • T6 37457901 ↗Post-COVID cognitive dysfunction: current status and research recommendations for high risk populati
  • T6 37372912 ↗What Do We Know about Nociplastic Pain?
  • T6 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
  • T6 36411394 ↗Depression and Anxiety During the COVID-19 Pandemic: Epidemiology, Mechanism, and Treatment
transcranial magnetic stimulation (TMS)
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
23 sources
  • T6REGISTERED-ONLY NCT07525063 ↗Pain & Reward Neuromodulation of CNS Circuits
  • T6INDIRECT 39025832 ↗Evaluating the effects of tDCS on depressive and anxiety symptoms from a transdiagnostic perspective
  • T1 38329083 ↗Efficacy and safety of transcranial magnetic stimulation on cognition in mild cognitive impairment,
  • T6INDIRECT 34752489 ↗A mixed-methods systematic review of post-viral fatigue interventions: Are there lessons for long Co
  • T6INDIRECT 38695969 ↗Intervention modalities for brain fog caused by long-COVID: systematic review of the literature
  • T6INDIRECT 40234864 ↗Exploring depression in adults over a decade: a review of longitudinal studies
  • T1 36129719 ↗Effectiveness of Standard Sequential Bilateral Repetitive Transcranial Magnetic Stimulation vs Bilat
  • T1 38228914 ↗Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for
  • T6INDIRECT 36455453 ↗Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABA<sub>B</sub>-ergic activity and cor
  • T6INDIRECT 38561682 ↗A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people wi
  • T1 36610206 ↗Real world research on transcranial magnetic stimulation treatment strategies for neuropsychiatric s
  • T6 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6INDIRECT 35912863 ↗Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches
  • T6INDIRECT 33537521 ↗Potential for increased prevalence of neuropathic pain after the COVID-19 pandemic
  • T6INDIRECT 35747600 ↗Clinical Characteristics and Mechanisms of Musculoskeletal Pain in Long COVID
  • T6INDIRECT 34403043 ↗Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor's pag
  • T6 37907497 ↗The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of lon
  • T6 36174571 ↗Bioelectronic medicine: Preclinical insights and clinical advances
  • T6 37372912 ↗What Do We Know about Nociplastic Pain?
  • T6 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
  • T6 35734582 ↗Non-invasive brain stimulation and neuroenhancement
umbilical cord mesenchymal stem cell
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
16 sources
  • T1REGISTERED-ONLY NCT06492798 ↗Effectiveness and Safety of Mesenchymal Stem Cell Therapy in Long COVID Patients
  • T6INDIRECT 35782071 ↗Association between Mesenchymal Stem Cells and COVID-19 Therapy: Systematic Review and Current Trend
  • T6 35787632 ↗Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next g
  • T6 38152837 ↗Engineered Exosome for Drug Delivery: Recent Development and Clinical Applications
  • T6 34363275 ↗Mesenchymal stem cells and their derived exosomes to combat Covid-19
  • T6HARM 38931833 ↗Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Pre
  • T6 38738585 ↗Extracellular vesicles as human therapeutics: A scoping review of the literature
  • T6INDIRECT 34072708 ↗The 15-Months Clinical Experience of SARS-CoV-2: A Literature Review of Therapies and Adjuvants
  • T4 37763198 ↗Fresh Umbilical Cord Blood-A Source of Multipotent Stem Cells, Collection, Banking, Cryopreservation
  • T6INDIRECT 39760094 ↗Persistent microbial infections and idiopathic pulmonary fibrosis - an insight into &lt;i&gt;non-typ
  • T6INDIRECT 38005826 ↗Immune-Cell-Based Therapy for COVID-19: Current Status
  • T6INDIRECT 36323940 ↗The 48<sup>th</sup> Annual Meeting of the European Society for Blood and Marrow Transplantation: Phy
  • T6INDIRECT 39444918 ↗Efficacy and safety of mesenchymal stem cell therapy for acute respiratory distress syndrome-a syste
  • T6 36359762 ↗Mesenchymal Stem Cell-Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Appli
  • T6 38888007 ↗Standardized Reporting of Research on Exosomes to Ensure Rigor and Reproducibility
  • T6 40720603 ↗Extracellular Vesicles for Clinical Diagnostics: From Bulk Measurements to Single-Vesicle Analysis
vagus nerve stimulation (VNS)
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
26 sources
  • T1REGISTERED-ONLY NCT06968104 ↗Vagus Nerve Stimulation to the Ear to Improve Symptoms in Post-COVID-19 and ME/CFS
  • T6INDIRECT 40514644 ↗Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in ov
  • T6INDIRECT 35768406 ↗Interventions for mental health, cognition, and psychological wellbeing in long COVID: a systematic
  • T6INDIRECT 36642173 ↗A systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19
  • T6INDIRECT 38214047 ↗Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation
  • T6INDIRECT 34291812 ↗Interventions for the prevention of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 36062970 ↗Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 34291813 ↗Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 36063364 ↗Interventions for the prevention of persistent post-COVID-19 olfactory dysfunction
  • T6INDIRECT 36710253 ↗Interleukin-17 as a spatiotemporal bridge from acute to chronic inflammation: Novel insights from co
  • T6INDIRECT 39089436 ↗Non-Invasive Brain Stimulation for Post-COVID-19 Conditions: A Systematic Review
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 36412084 ↗Long COVID: mechanisms, risk factors and recovery
  • T6INDIRECT 39482575 ↗Hallmarks of primary headache: part 1 - migraine
  • T6INDIRECT 37845499 ↗Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions
  • T4 39363044 ↗Vagus nerve stimulation (VNS): recent advances and future directions
  • T6INDIRECT 33677650 ↗Is postural orthostatic tachycardia syndrome (POTS) a central nervous system disorder?
  • T6INDIRECT 36853484 ↗Pain Management in the Post-COVID Era-An Update: A Narrative Review
  • T6INDIRECT 35978881 ↗Altered gut microbiota patterns in COVID-19: Markers for inflammation and disease severity
  • T6INDIRECT 36169154 ↗Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of aut
  • T4 32743022 ↗Targeting the cholinergic anti-inflammatory pathway with vagus nerve stimulation in patients with Co
  • T6 36174571 ↗Bioelectronic medicine: Preclinical insights and clinical advances
  • T6 35566253 ↗The Pathophysiology of Long COVID throughout the Renin-Angiotensin System
  • T6 37028776 ↗Neuroimmune nexus in the pathophysiology and therapy of inflammatory disorders: Role of α7 nicotinic
  • T6 34211370 ↗Microglial Implications in SARS-CoV-2 Infection and COVID-19: Lessons From Viral RNA Neurotropism an
  • T6 33324324 ↗Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19
vitamin D
T1
T1 — RCT in LC/PASC/PACVS
Long COVID
26 sources
  • T1 NCT05630339 ↗Magnesium and Vitamin D Combination for Post-COVID Syndrome
  • T1 NCT05356936 ↗Pilot Study of Vitamin K2 (MK-7) and Vitamin D3 Supplementation and the Effects on PASC Symptomatolo
  • T6 NCT02965898 ↗The Effect of Vitamin D Substitution on the Development of Chronic Pancreatitis
  • T1 34160843 ↗Association of vitamin D deficiency with COVID-19 infection severity: Systematic review and meta-ana
  • T6INDIRECT 34523128 ↗Continuing education meetings and workshops: effects on professional practice and healthcare outcome
  • T6INDIRECT 34318930 ↗Ivermectin for preventing and treating COVID-19
  • T6INDIRECT 36032234 ↗Post-COVID-19 fatigue: A systematic review
  • T1 34165766 ↗Vitamin D supplementation and clinical outcomes in COVID-19: a systematic review and meta-analysis
  • T6INDIRECT 36606682 ↗Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstr
  • T6INDIRECT 36695483 ↗Remdesivir for the treatment of COVID-19
  • T1 36215226 ↗Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respirat
  • T6INDIRECT 35450527 ↗Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combined with Olfactory Training to Tr
  • T6INDIRECT 33126054 ↗Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 33753937 ↗Post-acute COVID-19 syndrome
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 35594336 ↗Pathophysiology and mechanism of long COVID: a comprehensive review
  • T6INDIRECT 34328636 ↗Post-COVID-19 acute sarcopenia: physiopathology and management
  • T6INDIRECT 32773996 ↗The 2019-2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint
  • T6 34248921 ↗Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Con
  • T6 36454715 ↗CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond
  • T6 34991982 ↗An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
  • T6 38676447 ↗Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
  • T6 33001410 ↗Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss
whole body hyperthermia
T1
T1 — RCT in LC/PASC/PACVS
RegisteredLong COVID
14 sources
  • T1REGISTERED-ONLY NCT05931497 ↗Sauna for Long Covid
  • T6INDIRECT 41415232 ↗Integrative multimodal treatment approach for patients suffering from Post-COVID syndrome: a study b
  • T6 39967803 ↗Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorder
  • T6 38269219 ↗Nutritional and Wellness Strategies for Neurological and Psychiatric Recovery From Post-COVID Syndro
  • T6INDIRECT 36412591 ↗A Multimodal Approach in the Treatment of Persistent Post-COVID
  • T6 39274303 ↗Impact of Spa Therapy on Symptoms and Quality of Life in Post-COVID-19 Patients with Chronic Conditi
  • T6 37190098 ↗A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages
  • T6INDIRECT 41741003 ↗Assessment and management of post-COVID-19 pulmonary complications: a rapid review
  • T4 40336247 ↗Whole-body hyperthermia as part of a multimodal treatment for patients with post-covid syndrome - a
  • T4 PMC9471381 ↗ICIMH 2022 Abstracts
  • T4 PMC11047233 ↗2024 International Congress on Integrative Medicine & Health Abstracts
  • T6 42174604 ↗Reframing ME/CFS: toward a unified mechanistic model of chronic post-infectious diseases
  • T6 PMC10806386 ↗Nutritional and Wellness Strategies for Neurological and Psychiatric Recovery From Post-COVID Syndro
  • T6 PMC13300933 ↗Sleep and Circadian Rhythms in Patients with Physical and Mental Disorders
intravenous immunoglobulin (IVIg)
T2
T2 — RCT in related condition
RegisteredLong COVIDPOTS
45 sources
  • T6 NCT05350774 ↗Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
  • T6 32744608 ↗Expanded Clinical Phenotype, Oncological Associations, and Immunopathologic Insights of Paraneoplast
  • T6 29661905 ↗Randomized study of adjunctive belimumab in participants with generalized myasthenia gravis.
  • T6 22561833 ↗IgE and mast cells in allergic disease.
  • T6 25517090 ↗Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions.
  • T6 31676858 ↗TIM3 comes of age as an inhibitory receptor.
  • T6INDIRECT 33837630 ↗Prevalence, clinical characteristics and outcomes of Guillain-Barré syndrome spectrum associated wit
  • T6INDIRECT 35660931 ↗Global reports of myocarditis following COVID-19 vaccination: A systematic review and meta-analysis
  • T6INDIRECT 34365148 ↗Vaccine-induced immune thrombotic thrombocytopenia and cerebral venous sinus thrombosis post COVID-1
  • T6INDIRECT 34386902 ↗Association of CNS demyelination and COVID-19 infection: an updated systematic review
  • T6INDIRECT 33036570 ↗Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
  • T6INDIRECT 32454187 ↗Review of trials currently testing treatment and prevention of COVID-19
  • T6INDIRECT 35316551 ↗A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendat
  • T6INDIRECT 35752132 ↗Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccinati
  • T6INDIRECT 36098903 ↗Guillain-Barré syndrome in association with COVID-19 vaccination: a systematic review
  • T6 36695182 ↗Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
  • T6 33753937 ↗Post-acute COVID-19 syndrome
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6INDIRECT 34542573 ↗Use and Safety of Immunotherapeutic Management of N-Methyl-d-Aspartate Receptor Antibody Encephaliti
  • T6INDIRECT 32840686 ↗Guillain-Barré syndrome spectrum associated with COVID-19: an up-to-date systematic review of 73 cas
  • T6INDIRECT 32855289 ↗Guillain-Barré syndrome in SARS-CoV-2 infection: an instant systematic review of the first six month
  • T6INDIRECT 33949300 ↗Guillain Barre Syndrome as a Complication of COVID-19: A Systematic Review
  • T2 31782181 ↗Randomized Placebo-Controlled Trial of Intravenous Immunoglobulin in Autoimmune LGI1/CASPR2 Epilepsy
  • T6INDIRECT 23168581 ↗Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a ra
  • T2 21745374 ↗Comparison of intravenous immunoglobulin and plasma exchange in treatment of mechanically ventilated
  • T2 8774401 ↗Intravenous immunoglobulin treatment in paraneoplastic neurological syndromes with antineuronal auto
  • T6 31541214 ↗Diagnosis and management of Guillain-Barré syndrome in ten steps
  • T6INDIRECT 23633371 ↗Interventions for treating pain and disability in adults with complex regional pain syndrome
  • T6INDIRECT 32653054 ↗Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally a
  • T6INDIRECT 38264914 ↗2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 32201335 ↗Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID
  • T6INDIRECT 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 34281357 ↗Myocarditis With COVID-19 mRNA Vaccines
  • T6INDIRECT 33903743 ↗Systemic and organ-specific immune-related manifestations of COVID-19
  • T6 36707719 ↗The role of platelets in immune-mediated inflammatory diseases
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 33219837 ↗Severe COVID-19, multisystem inflammatory syndrome in children, and Kawasaki disease: immunological
  • T6 34716418 ↗Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison
  • T6 34454673 ↗1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study
  • T6INDIRECT 24462240 ↗Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a c
  • T6INDIRECT 30218025 ↗Mechanisms, biomarkers and targets for adult-onset Still's disease
  • T6 23642721 ↗Guillain-Barré syndrome and variants
  • T6 33894193 ↗Challenges in the diagnosis of Parkinson's disease
  • T6 26659576 ↗Neurotropic virus infections as the cause of immediate and delayed neuropathology
  • T6 30285773 ↗Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
probiotics
T2
T2 — RCT in related condition
RegisteredLong COVIDME/CFS
49 sources
  • T2REGISTERED-ONLY NCT03773003 ↗Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue (CFS/ME)
  • T6 30721959 ↗Mechanisms of Action of Probiotics.
  • T6 29976412 ↗Benefaction of probiotics for human health: A review.
  • T6INDIRECT 35057437 ↗Effectiveness of Curcumin on Outcomes of Hospitalized COVID-19 Patients: A Systematic Review of Clin
  • T6INDIRECT 34791425 ↗The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the mus
  • T6INDIRECT 34131481 ↗Global prevalence of prolonged gastrointestinal symptoms in COVID-19 survivors and potential pathoge
  • T6INDIRECT 39603702 ↗Interventions for the management of long covid (post-covid condition): living systematic review
  • T6INDIRECT 39774607 ↗Mucosal immune response in biology, disease prevention and treatment
  • T6INDIRECT 36349400 ↗Clinical trials on the pharmacological treatment of long COVID: A systematic review
  • T6INDIRECT 35409389 ↗Benefits and Implications of Resveratrol Supplementation on Microbiota Modulations: A Systematic Rev
  • T6INDIRECT 35893864 ↗The Efficacy of Vitamin D Supplementation in the Treatment of Fibromyalgia Syndrome and Chronic Musc
  • T6INDIRECT 38424099 ↗Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised control
  • T6INDIRECT 39073834 ↗Fecal Microbiota Transplantation for Treatment of Parkinson Disease: A Randomized Clinical Trial
  • T6 36639608 ↗Long COVID: major findings, mechanisms and recommendations
  • T6 39866113 ↗2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Ass
  • T6INDIRECT 30480772 ↗Fecal transplantation for treatment of inflammatory bowel disease
  • T6INDIRECT 25793197 ↗The role of probiotic lactic acid bacteria and bifidobacteria in the prevention and treatment of inf
  • T2 25400447 ↗Modulation of immunity and inflammatory gene expression in the gut, in inflammatory diseases of the
  • T6INDIRECT 23842110 ↗Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut
  • T6INDIRECT 28943228 ↗Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiet
  • T6INDIRECT 27208120 ↗Fermented Milk Containing Lactobacillus casei Strain Shirota Preserves the Diversity of the Gut Micr
  • T6INDIRECT 35654766 ↗Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a ra
  • T2 31478755 ↗Probiotics for Gastrointestinal Symptoms and Quality of Life in Autism: A Placebo-Controlled Pilot T
  • T6INDIRECT 31752370 ↗Effect of <i>Lactobacillus plantarum</i> TWK10 on Exercise Physiological Adaptation, Performance, an
  • T6 32582143 ↗The Genus <i>Alistipes</i>: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Men
  • T6 30317530 ↗An insight into gut microbiota and its functionalities
  • T6INDIRECT 37451743 ↗Faecalibacterium: a bacterial genus with promising human health applications
  • T6INDIRECT 36271144 ↗Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications
  • T6INDIRECT 34328636 ↗Post-COVID-19 acute sarcopenia: physiopathology and management
  • T6INDIRECT 36364899 ↗A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
  • T6INDIRECT 36851614 ↗Persistent SARS-CoV-2 Infection, EBV, HHV-6 and Other Factors May Contribute to Inflammation and Aut
  • T6INDIRECT 36385449 ↗Neuropsychiatric aspects of long COVID: A comprehensive review
  • T6 37130947 ↗Metformin: update on mechanisms of action and repurposing potential
  • T6 39326415 ↗Mechanisms of long COVID and the path toward therapeutics
  • T6 33909761 ↗Brazilian Guidelines of Hypertension - 2020
  • T6 34366606 ↗Pancreatic cancer: A review of epidemiology, trend, and risk factors
  • T6INDIRECT 21871249 ↗Treating Clostridium difficile infection with fecal microbiota transplantation
  • T6INDIRECT 25402818 ↗The gut microbiome and the brain
  • T4 32010640 ↗How Probiotics Affect the Microbiota
  • T6INDIRECT 28503135 ↗The Gut Microbiota and Autism Spectrum Disorders
  • T4 28555037 ↗Evidence of the Anti-Inflammatory Effects of Probiotics and Synbiotics in Intestinal Chronic Disease
  • T6INDIRECT 25365763 ↗Interoceptive dysfunction: toward an integrated framework for understanding somatic and affective di
  • T6 24092857 ↗Recent advances in understanding enteric pathogenic Escherichia coli
  • T6 23759244 ↗Psychobiotics: a novel class of psychotropic
  • T6 31076401 ↗Leaky gut: mechanisms, measurement and clinical implications in humans
  • T6 26528128 ↗Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatr
  • T6 29276734 ↗Stress & the gut-brain axis: Regulation by the microbiome
  • T6 25392516 ↗Gut microbes and the brain: paradigm shift in neuroscience
  • T6 27159638 ↗Irritable bowel syndrome
Pathological sequelae of long-haul COVID
T4
T4 — Case series
Long COVID
7 sources
  • T6 35105985 ↗Pathological sequelae of long-haul COVID.
  • T6 36148558 ↗Neurological post-acute sequelae of SARS-CoV-2 infection
  • T6INDIRECT 35464182 ↗Case Report: Therapeutic and immunomodulatory effects of plasmapheresis in long-haul COVID
  • T6 36288544 ↗Multimodal neuroimaging in post-COVID syndrome and correlation with cognition
  • T6 37395896 ↗Knowledge mapping of COVID-19 and autoimmune diseases: a visual and bibliometric analysis
  • T6INDIRECT 40098132 ↗Abstracts of the 35th Meeting of the German Society for Pediatric and Adolescents Rheumatology (Gese
  • T4 PMC9548758 ↗SLEEP-DISORDERED BREATHING AND LONG-HAUL COVID-19: A CASE REPORT
Overview of Biological Factors That May Contribute to Persistent Symptoms
T6
T6 — Mechanistic / preclinical
Long COVID
7 sources
  • T6 34248921 ↗Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Con
  • T6INDIRECT 41869328 ↗Global trends in research of neuroimmune in lung diseases over past decade: a bibliometric analysis
  • T6 36169154 ↗Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of aut
  • T6 37395896 ↗Knowledge mapping of COVID-19 and autoimmune diseases: a visual and bibliometric analysis
  • T6 38293444 ↗Visual analysis of hotspots and trends in long COVID research based on bibliometric
  • T6 36846620 ↗Stress, Asthenia, and Cognitive Disorders
  • T6 36818497 ↗[Genomics in Public Health Scientific evidence and prospects for integration in the prevention pract